2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine
- Product Name
- 2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine
- CAS No.
- 117519-08-1
- Chemical Name
- 2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine
- Synonyms
- 5-nitro-6-(trifluoromethyl)picolinonitrile;2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine;2-Chloro-6-(trifluoromethyl)-3-nitropyridine;2-cloro-3-nitro-6-(trifluoromethyl) pyridine;Pyridine,2-chloro-3-nitro-6-(trifluoromethyl)-;2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine ISO 9001：2015 REACH
- CBNumber
- CB4950110
- Molecular Formula
- C6H2ClF3N2O2
- Formula Weight
- 226.54
- MOL File
- 117519-08-1.mol
2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine Property
- Boiling point:
- 242℃
- Density
- 1.618
- Flash point:
- 100℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -7.04±0.10(Predicted)
- Appearance
- Light yellow to yellow Liquid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C596115
- Product name
- 2-Chloro-3-nitro-6-(trifluoromethyl)pyridine
- Packaging
- 100mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- C596115
- Product name
- 2-Chloro-3-nitro-6-(trifluoromethyl)pyridine
- Packaging
- 250mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- FC105701
- Product name
- 2-chloro-3-nitro-6-(trifluoromethyl)pyridine
- Packaging
- 100mg
- Price
- $135
- Updated
- 2021/12/16
- Product number
- PC2661
- Product name
- 2-Chloro-3-nitro-6-(trifluoromethyl)pyridine
- Packaging
- 1g
- Price
- $255
- Updated
- 2021/12/16
- Product number
- FC105701
- Product name
- 2-chloro-3-nitro-6-(trifluoromethyl)pyridine
- Packaging
- 250mg
- Price
- $260
- Updated
- 2021/12/16
2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine Chemical Properties,Usage,Production
Uses
2-Chloro-3-nitro-6-(trifluoromethyl)pyridine
Synthesis
117519-09-2
117519-08-1
General procedure for the synthesis of 2-chloro-3-nitro-6-trifluoromethylpyridine from 2-chloro-6-trifluoromethyl-3-amino-pyridine: To a mixture of fuming sulfuric acid (3.2 mL) and aqueous hydrogen peroxide (50%, 1.6 mL) was slowly added a solution of 3-amino-2-chloro-6-(trifluoromethyl)pyridine in concentrated sulfuric acid (4 mL) at 0°C (304 mg. 1.55 mmol). The reaction mixture was slowly warmed to 25 °C and stirred at this temperature for 20 hours. After completion of the reaction, the mixture was carefully poured into ice water. The reaction mixture was neutralized with aqueous ammonium hydroxide and subsequently extracted with ethyl acetate (5 x 10 mL). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the target compound 2-chloro-3-nitro-6-trifluoromethylpyridine (126 mg, 36% yield) as a yellow solid, which could be used in subsequent reactions without further purification.
References
[1] Patent: WO2006/65703, 2006, A1. Location in patent: Page/Page column 107
[2] Patent: WO2012/12366, 2012, A1. Location in patent: Page/Page column 41
2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine manufacturers
- Product
- 2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine 117519-08-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-30
- Product
- 2-Chloro-3-Nitro-6-Trifluoromethyl Pyridine 117519-08-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24