2-Chloro-6-(trifluoromethyl)pyridine

Product Name: 2-Chloro-6-(trifluoromethyl)pyridine
CAS No.: 39890-95-4
Chemical Name: 2-Chloro-6-(trifluoromethyl)pyridine
Synonyms: FINE ORGANIC COMPOUND;oro-6-(trifL;PYRIDINE DERIVAT;BUTTPARK 27\08-82;Chloro-6-(trifluoroMethyl)pyr;2-Chloro-5-trifluoromethylpyri;2-CHLORO-6-TRIFLUOROMETHYLPRIDINE;6-Chloro-2-(trifluoromethyl)pyridine;2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE;PYRIDINE, 2-CHLORO-6-(TRIFLUOROMETHYL)-
CBNumber: CB2241526
Molecular Formula: C6H3ClF3N
Formula Weight: 181.54
MOL File: 39890-95-4.mol

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2-Chloro-6-(trifluoromethyl)pyridine Property

Melting point:: 33 °C
Boiling point:: 60-62°C 8mm
Density: 1.416±0.06 g/cm3(Predicted)
Flash point:: 78°C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
Water Solubility: Insoluble in water
form: powder to lump
pka: -4.30±0.10(Predicted)
color: White to Almost white
FreezingPoint: 32.0 to 34.0 ℃
BRN: 4308910
InChI: InChI=1S/C6H3ClF3N/c7-5-3-1-2-4(11-5)6(8,9)10/h1-3H
InChIKey: ADVQMCQMDHBTHJ-UHFFFAOYSA-N
SMILES: C1(Cl)=NC(C(F)(F)F)=CC=C1
CAS DataBase Reference: 39890-95-4(CAS DataBase Reference)

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Safety

Hazard Codes: T;Xn,Xi,Xn,T
Risk Statements: 25-20/21/22-36/37/38-36
Safety Statements: 26-36/37/39-45-36/37-9-36
RIDADR: 2811
WGK Germany: 3
Hazard Note: Irritant
HazardClass: 6.1
PackingGroup: III
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 684724
Product name: 2-Chloro-6-(trifluoromethyl)pyridine
Purity: 96%
Packaging: 1g
Price: $25
Updated: 2023/06/20

TCI Chemical

Product number: C1986
Product name: 2-Chloro-6-(trifluoromethyl)pyridine
Purity: >98.0%(GC)
Packaging: 1g
Price: $40
Updated: 2025/07/31

TCI Chemical

Product number: C1986
Product name: 2-Chloro-6-(trifluoromethyl)pyridine
Purity: >98.0%(GC)
Packaging: 5g
Price: $119
Updated: 2025/07/31

TRC

Product number: C432960
Product name: 2-Chloro-6-(trifluoromethyl)pyridine
Packaging: 1g
Price: $55
Updated: 2021/12/16

Matrix Scientific

Product number: 007184
Product name: 2-Chloro-6-(trifluoromethyl)pyridine
Purity: 98%
Packaging: 25g
Price: $20
Updated: 2021/12/16

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2-Chloro-6-(trifluoromethyl)pyridine Chemical Properties,Usage,Production

Chemical Properties

Colorless to off-white liquid (or White to off-white crystal)

Uses

2-Chloro-6-(trifluoromethyl)pyridine can be used in the synthesis of medicine, pesticide or biocidal product.

Chemical Reactivity

2-Chloro-6-(trifluoromethyl)pyridine is stable under recommended storage conditions, it reacts with strong oxidizing agents, strong acids, strong bases.

Synthesis

1929-82-4

39890-95-4

General procedure for the synthesis of 2-chloro-6-trichloromethylpyridine from 2-chloro-6-trichloromethylpyridine: 2-chloro-6-trichloromethylpyridine (700 g, 3.03 mol, feed rate 1.24 g/min) and anhydrous hydrogen fluoride (936 g, 46.8 mol, feed rate 1.66 g/min) were added successively to a tubular reactor fitted with a preactivated chromium oxide-alumina catalyst (210 g) in a tubular reactor at a reaction temperature of 330 °C. The reaction products were cooled with ice water and collected. The reaction products were collected after cooling with ice water and extracted with dichloromethane. The extract was washed with 10% potassium hydroxide solution, and the organic layer was separated and concentrated to give 490.0 g of crude 2-chloro-6-trifluoromethylpyridine, which was analyzed by GC for 95.03% purity and 89% reaction yield. The crude product was purified by fractionation to obtain 2-chloro-6-trifluoromethylpyridine with 98.0% purity and 80.0% yield.

References

[1] Patent: WO2016/178248, 2016, A1. Location in patent: Page/Page column 5

2-Chloro-6-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Chloro-6-(trifluoromethyl)pyridine Suppliers

Americas 1 Belgium 1 China 306 Europe 3 France 1 Germany 5 India 6 Italy 1 Japan 4 Poland 1 Switzerland 3 Ukraine 1 United Kingdom 22 United States 60 Global 415

Shanghai Sphchem Co., Ltd.

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ShangHai DEMO Chemical Co.,Ltd

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Energy Chemical

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View Lastest Price from 2-Chloro-6-(trifluoromethyl)pyridine manufacturers

Shandong Jihui Chemical Co., Ltd.

Product: 2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4
Price: US $0.00-0.00/KG
Min. Order: 250KG
Purity: Purity: 99%
Supply Ability: 1000tons
Release date: 2025-07-20

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-24

Dideu Industries Group Limited

Product: 2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-25

39890-95-4, 2-Chloro-6-(trifluoromethyl)pyridineRelated Search:

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BUTTPARK 27\08-82

PYRIDINE, 2-CHLORO-6-(TRIFLUOROMETHYL)-

2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE

6-Chloro-2-(trifluoromethyl)pyridine

2-CHLORO-6-TRIFLUOROMETHYLPRIDINE

2-Chloro-5-trifluoromethylpyri

2-CHLORO-6-TRIFLUOROMETHYL-PYRIDINE >97%

oro-6-(trifL

6-Chloro-alpha,alpha,alpha-trifluoro-2-picoline

Chloro-6-(trifluoroMethyl)pyr

2-chloro -6-three fluorineMethyl pyridine

FINE ORGANIC COMPOUND

PYRIDINE DERIVAT

2-Chloro-6-(trifluoromethyl)pyridine&gt

2-Chloro-6-(trifluoromethyl)pyridine ISO 9001：2015 REACH

2-Chloro-6-(trifluoromethyl)pyridine, ≥ 98.0%

39890-95-4

39890-95-7

30.9890-95-4

1478-14-8

C6H3CIF3N

C6F3H3ClN

C6H3ClF3N

Heterocyclic Building Blocks

Halogenated Heterocycles

Pyridines

Chloropyridines

Halopyridines

Building Blocks

Fluorine series

alkyl chloride

Chloropyridines

Halopyridines

C6Heterocyclic Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

Pyridine series

Pyridines, Pyrimidines, Purines and Pteredines

Pyridines

Pyridine

Pyridines derivates

Halides

Heterocycles