2-Chloro-6-(trifluoromethyl)pyridine
- Product Name
- 2-Chloro-6-(trifluoromethyl)pyridine
- CAS No.
- 39890-95-4
- Chemical Name
- 2-Chloro-6-(trifluoromethyl)pyridine
- Synonyms
- FINE ORGANIC COMPOUND;oro-6-(trifL;PYRIDINE DERIVAT;BUTTPARK 27\08-82;Chloro-6-(trifluoroMethyl)pyr;2-Chloro-5-trifluoromethylpyri;2-CHLORO-6-TRIFLUOROMETHYLPRIDINE;6-Chloro-2-(trifluoromethyl)pyridine;2-CHLORO-6-(TRIFLUOROMETHYL)PYRIDINE;PYRIDINE, 2-CHLORO-6-(TRIFLUOROMETHYL)-
- CBNumber
- CB2241526
- Molecular Formula
- C6H3ClF3N
- Formula Weight
- 181.54
- MOL File
- 39890-95-4.mol
2-Chloro-6-(trifluoromethyl)pyridine Property
- Melting point:
- 33 °C
- Boiling point:
- 60-62°C 8mm
- Density
- 1.416±0.06 g/cm3(Predicted)
- Flash point:
- 78°C
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- Water Solubility
- Insoluble in water
- form
- powder to lump
- pka
- -4.30±0.10(Predicted)
- color
- White to Almost white
- FreezingPoint
- 32.0 to 34.0 ℃
- BRN
- 4308910
- InChI
- InChI=1S/C6H3ClF3N/c7-5-3-1-2-4(11-5)6(8,9)10/h1-3H
- InChIKey
- ADVQMCQMDHBTHJ-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC(C(F)(F)F)=CC=C1
- CAS DataBase Reference
- 39890-95-4(CAS DataBase Reference)
Safety
- Hazard Codes
- T;Xn,Xi,Xn,T
- Risk Statements
- 25-20/21/22-36/37/38-36
- Safety Statements
- 26-36/37/39-45-36/37-9-36
- RIDADR
- 2811
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 684724
- Product name
- 2-Chloro-6-(trifluoromethyl)pyridine
- Purity
- 96%
- Packaging
- 1g
- Price
- $25
- Updated
- 2023/06/20
- Product number
- C1986
- Product name
- 2-Chloro-6-(trifluoromethyl)pyridine
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- C1986
- Product name
- 2-Chloro-6-(trifluoromethyl)pyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $119
- Updated
- 2025/07/31
- Product number
- C432960
- Product name
- 2-Chloro-6-(trifluoromethyl)pyridine
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 007184
- Product name
- 2-Chloro-6-(trifluoromethyl)pyridine
- Purity
- 98%
- Packaging
- 25g
- Price
- $20
- Updated
- 2021/12/16
2-Chloro-6-(trifluoromethyl)pyridine Chemical Properties,Usage,Production
Chemical Properties
Colorless to off-white liquid (or White to off-white crystal)
Uses
2-Chloro-6-(trifluoromethyl)pyridine can be used in the synthesis of medicine, pesticide or biocidal product.
Chemical Reactivity
2-Chloro-6-(trifluoromethyl)pyridine is stable under recommended storage conditions, it reacts with strong oxidizing agents, strong acids, strong bases.
Synthesis
1929-82-4
39890-95-4
General procedure for the synthesis of 2-chloro-6-trichloromethylpyridine from 2-chloro-6-trichloromethylpyridine: 2-chloro-6-trichloromethylpyridine (700 g, 3.03 mol, feed rate 1.24 g/min) and anhydrous hydrogen fluoride (936 g, 46.8 mol, feed rate 1.66 g/min) were added successively to a tubular reactor fitted with a preactivated chromium oxide-alumina catalyst (210 g) in a tubular reactor at a reaction temperature of 330 °C. The reaction products were cooled with ice water and collected. The reaction products were collected after cooling with ice water and extracted with dichloromethane. The extract was washed with 10% potassium hydroxide solution, and the organic layer was separated and concentrated to give 490.0 g of crude 2-chloro-6-trifluoromethylpyridine, which was analyzed by GC for 95.03% purity and 89% reaction yield. The crude product was purified by fractionation to obtain 2-chloro-6-trifluoromethylpyridine with 98.0% purity and 80.0% yield.
References
[1] Patent: WO2016/178248, 2016, A1. Location in patent: Page/Page column 5
2-Chloro-6-(trifluoromethyl)pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-6-(trifluoromethyl)pyridine Suppliers
- Tel
- --
- Fax
- --
- biuro@pol-aura.pl
- Country
- Poland
- ProdList
- 1453
- Advantage
- 58
View Lastest Price from 2-Chloro-6-(trifluoromethyl)pyridine manufacturers
- Product
- 2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 250KG
- Purity
- Purity: 99%
- Supply Ability
- 1000tons
- Release date
- 2025-07-20
- Product
- 2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-24
- Product
- 2-Chloro-6-(trifluoromethyl)pyridine 39890-95-4
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-25