ChemicalBook > CAS DataBase List > 5-(Hydroxymethyl)-1-methyl-1H-pyrazole

5-(Hydroxymethyl)-1-methyl-1H-pyrazole

Product Name
5-(Hydroxymethyl)-1-methyl-1H-pyrazole
CAS No.
84547-61-5
Chemical Name
5-(Hydroxymethyl)-1-methyl-1H-pyrazole
Synonyms
1-Methylpyrazole-5-methanol;(2-methylpyrazol-3-yl)methanol;(2-methyl-3-pyrazolyl)methanol;1H-pyrazole-5-methanol, 1-methyl-;(1-Methyl-1H-pyrazol-5-yl)methanol;(2-Methyl-2H-pyrazol-3-yl)-methanol;5-(Hydroxymethyl)-1-methyl-1H-pyrazole;(1-methyl-1H-pyrazol-5-yl)methanol - [M87519]
CBNumber
CB4957487
Molecular Formula
C5H8N2O
Formula Weight
112.13
MOL File
84547-61-5.mol
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5-(Hydroxymethyl)-1-methyl-1H-pyrazole Property

Melting point:
55-59.5
Boiling point:
243.6±15.0 °C(Predicted)
Density 
1.16±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
form 
powder to crystal
pka
14.35±0.10(Predicted)
color 
White to Almost white
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Safety

Hazard Note 
Harmful
HS Code 
2933199090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2831
Product name
1-Methylpyrazole-5-methanol
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$159
Updated
2025/07/31
TCI Chemical
Product number
M2831
Product name
1-Methylpyrazole-5-methanol
Purity
>98.0%(GC)(T)
Packaging
200mg
Price
$40
Updated
2025/07/31
TRC
Product number
M321443
Product name
(1-Methyl-1H-pyrazol-5-yl)methanol
Packaging
500mg
Price
$130
Updated
2021/12/16
SynQuest Laboratories
Product number
4H01-1-U0
Product name
5-(Hydroxymethyl)-1-methyl-1H-pyrazole
Packaging
1g
Price
$71
Updated
2021/12/16
Chem-Impex
Product number
43621
Product name
1-Methylpyrazole-5-methanol,≥98%(GC)
Purity
≥98%(GC)
Packaging
1G
Price
$124.8
Updated
2021/12/16
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5-(Hydroxymethyl)-1-methyl-1H-pyrazole Chemical Properties,Usage,Production

Synthesis

16034-46-1

84547-61-5

1-Methyl-1H-pyrazole-5-carboxylic acid (2 g, 15.86 mmol) was dissolved in tetrahydrofuran (50 mL) at 0 °C and in an inert atmosphere, followed by batchwise addition of lithium aluminum hydride (LiAlH4, 720 mg, 18.97 mmol). The reaction system was stirred under nitrogen protection at room temperature for 2 hours. Upon completion of the reaction, water (2 mL) was slowly added to quench the reaction. The mixture was dried over anhydrous sodium sulfate and filtered to remove the solid. The filtrate was concentrated under reduced pressure to afford the target product (1-methyl-1H-pyrazol-5-yl)methanol as a colorless oil (1.2 g, 67% yield). Mass spectrum (ESI, m/z): [M + H]+ 113.0. 1H NMR (300 MHz, CDCl3) δ 7.36 (d, J = 1.8 Hz, 1H), 6.18 (d, J = 1.8 Hz, 1H), 4.66 (s, 2H), 3.88 (s, 3H).

References

[1] Patent: WO2014/66795, 2014, A1. Location in patent: Paragraph 0175
[2] J. Gen. Chem. USSR (Engl. Transl.), 1982, vol. 52, # 11, p. 2297 - 2303
[3] Zhurnal Obshchei Khimii, 1982, vol. 52, # 11, p. 2598 - 2605
[4] Patent: WO2014/151142, 2014, A1
[5] Patent: WO2016/29454, 2016, A1. Location in patent: Page/Page column 64

5-(Hydroxymethyl)-1-methyl-1H-pyrazole Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(Hydroxymethyl)-1-methyl-1H-pyrazole Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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China
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PharmaBlock Sciences (Nanjing),Inc.
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TCI (Shanghai) Development Co., Ltd.
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Shanghai Topbiochem Technology Co., Ltd
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View Lastest Price from 5-(Hydroxymethyl)-1-methyl-1H-pyrazole manufacturers

Shanghai kingmorn biotechnology Co.,LTD.
Product
5-(Hydroxymethyl)-1-methyl-1H-pyrazole 84547-61-5
Price
US $0.00-0.00/KG
Min. Order
10g
Purity
98%
Supply Ability
>10kg
Release date
2021-07-09
Career Henan Chemical Co
Product
5-(Hydroxymethyl)-1-methyl-1H-pyrazole 84547-61-5
Price
US $500.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2018-08-04