FMOC-TYR-OME
- Product Name
- FMOC-TYR-OME
- CAS No.
- 82911-79-3
- Chemical Name
- FMOC-TYR-OME
- Synonyms
- FMOC-TYR-OME;Fmoc-L-Tyr-OMe;Fmoc-L-tyrosine Methyl Ester;N-Fmoc-L-tyrosine methyl ester;METHYL D-AMINOLEVULINATE HYDROCHLORIDE;(9H-Fluoren-9-yl)MethOxy]Carbonyl Tyr-OMe;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-tyrosine methyl ester;L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, methyl ester;(S)-Methyl 2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-3-(4-hydroxyphenyl)propanoate;methyl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-hydroxyphenyl)propanoate
- CBNumber
- CB51005414
- Molecular Formula
- C25H23NO5
- Formula Weight
- 417.45
- MOL File
- 82911-79-3.mol
FMOC-TYR-OME Property
- Melting point:
- 122-123 °C
- Boiling point:
- 645.2±55.0 °C(Predicted)
- Density
- 1.275±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 9.75±0.15(Predicted)
- Appearance
- White to off-white Solid
- optical activity
- 32.668° (C=0.01 g/ml, CHCL3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- AS102819
- Product name
- N-Fmoc-L-tyrosine methyl ester
- Purity
- 95% ee
- Packaging
- 5G
- Price
- $88
- Updated
- 2021/12/16
- Product number
- Y3480
- Product name
- Fmoc-Tyr-Ome
- Packaging
- 5g
- Price
- $170
- Updated
- 2021/12/16
- Product number
- AS102819
- Product name
- N-Fmoc-L-tyrosine methyl ester
- Purity
- 95% ee
- Packaging
- 25g
- Price
- $277
- Updated
- 2021/12/16
- Product number
- AAA0010615
- Product name
- FMOC-TYR-OME
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.13
- Updated
- 2021/12/16
- Product number
- AS102819
- Product name
- N-Fmoc-L-tyrosine methyl ester
- Purity
- 95% ee
- Packaging
- 100g
- Price
- $683
- Updated
- 2021/12/16
FMOC-TYR-OME Chemical Properties,Usage,Production
Synthesis
1240497-07-7
82911-79-3
GENERAL PROCEDURE: METHOD A-USE OF PLANETARY BALL MILL: Triphenylmethylated compounds (1 mmol; typically 563 mg, 4) and In(OTf)3 (141 mg, 0.25 mmol) were mixed in a 50 mL stainless steel (SS) jar with ten 10-mm diameter SS balls. The reaction was carried out in a planetary ball mill (PM-100) at 550 rpm for 3.5 h (the progress of the reaction was monitored by TLC and the unfolding agent was EtOAc:Hex, 1:1). Upon completion of the reaction, EtOAc was added to the mixture and the solution was transferred to a dispensing funnel (50 ml × 3). The organic phase was washed sequentially with 10% Na2CO3 aqueous solution (50 ml × 2) and water (50 ml), dried with Na2SO4 and concentrated under reduced pressure to obtain the crude de-O-tritylated product. The crude product was purified by fast chromatography to remove the by-product TrOH to give the pure product (yield: 305 mg, 95.2%, 5 from 4). The pure product was crystallized from ether-n-Hex to give an analytically pure product. The spectral data of the product was in agreement with the expected structure and literature values. Method B-Use of a Vibratory Ball Mill: the triphenylmethylated compound (1 mmol; typically 563 mg, 4) and In(OTf)3 (141 mg, 0.25 mmol) were mixed in a 10 mL stainless steel (SS) jar to which 20 SS balls of 3 mm diameter were added. The reaction was carried out in a vibrating ball mill (MM-400) at 30 Hz for 15 min (the progress of the reaction was monitored by TLC and the unfolding agent was EtOAc/Hex, 1:1). The post-treatment and isolation steps of the product were the same as in Method A. The yield was 308 mg, 96.2%, from 4 to 5.
References
[1] Carbohydrate Research, 2014, vol. 397, p. 18 - 26
FMOC-TYR-OME Preparation Products And Raw materials
Raw materials
Preparation Products
FMOC-TYR-OME Suppliers
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 021-61312847 13636370518
- Fax
- 021-55068248
- shyysw007@163.com
- Country
- China
- ProdList
- 4999
- Advantage
- 60
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 028-028-0000000 13008177686
- Fax
- 15928581901
- sales@ckcbiotech.com
- Country
- China
- ProdList
- 904
- Advantage
- 55
- Tel
- 0371-53765687 18937137882
- Fax
- QQ:2885373884
- 2853979813@qq.com
- Country
- China
- ProdList
- 7991
- Advantage
- 55
- Tel
- +86-21-61263340; 17609490614 13764994101
- Fax
- 021-61263399
- fisherwang@glschina.com
- Country
- China
- ProdList
- 8258
- Advantage
- 55
- Tel
- 0510-83583050 13771062561
- Fax
- 0510-83583039
- willsun@peptide-search.com
- Country
- China
- ProdList
- 6716
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 028-028-88457210 18190964009
- Fax
- QQ3213375147
- 3054240163@qq.com
- Country
- China
- ProdList
- 2293
- Advantage
- 55
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28785
- Advantage
- 58
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 021-61263370 18901917034
- xingli@glbiochem.com
- Country
- China
- ProdList
- 5637
- Advantage
- 58
- Tel
- 021-61263377 15023907684
- Fax
- 021-61263399
- 15800684150@163.com
- Country
- China
- ProdList
- 8131
- Advantage
- 58
- Tel
- +86-021-61263370 +86-18901917034
- Country
- CHINA
- ProdList
- 3904
- Advantage
- 58
- Tel
- +86-0571-81612335 +8613336028439
- sales@nextpeptide.com
- Country
- China
- ProdList
- 19908
- Advantage
- 58
- Tel
- +86-021-61263370 +8615301650015
- wuqiuyan@glschina.com
- Country
- China
- ProdList
- 2975
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0371-86658258
- laboratory@coreychem.com
- Country
- China
- ProdList
- 30229
- Advantage
- 58
- Tel
- 15021845385
- 765325601@qq.com
- Country
- China
- ProdList
- 3609
- Advantage
- 58
- Tel
- 021-61263389 13524856427
- Fax
- WeChat630417570
- Joetang@glschina.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- 021-61263375 18168859245
- Country
- China
- ProdList
- 5958
- Advantage
- 58
- Tel
- 15061806929
- linda-fu@mimotopes.cn
- Country
- China
- ProdList
- 5796
- Advantage
- 58
- Tel
- 18221292452
- fannieliu@glschina.com
- Country
- China
- ProdList
- 6798
- Advantage
- 58
- Tel
- 18217475093
- 1615396342@qq.com
- Country
- China
- ProdList
- 4309
- Advantage
- 58
- Tel
- 021-54721350 13524668266
- Fax
- 021-5
- 2881505714@qq.com
- Country
- China
- ProdList
- 7872
- Advantage
- 58
- Tel
- 021-61263455 13167021076
- amy@glschina.com
- Country
- China
- ProdList
- 9736
- Advantage
- 58
- Tel
- 0571-88760729 18072970094
- supports@ontorespeptide.com
- Country
- China
- ProdList
- 2696
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- +8618051385538
- donboo@donboo.com
- Country
- China
- ProdList
- 9363
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44119
- Advantage
- 58
- Tel
- 021-4007787-550 400-7787-550
- 2850202386@qq.com
- Country
- China
- ProdList
- 10582
- Advantage
- 58
- Tel
- 021-61109150
- Fax
- 021-61105897
- sales@tcisct.com
- Country
- China
- ProdList
- 29668
- Advantage
- 58
- Tel
- 400-8210725 4008210725
- malulu@leyan.com
- Country
- China
- ProdList
- 40000
- Advantage
- 58
- Tel
- 400-6005915
- sales@picasso-e.com
- Country
- China
- ProdList
- 39653
- Advantage
- 58
- Tel
- 02888457210; 18380436509
- Fax
- 0838-2822568
- 2065506070@qq.com
- Country
- China
- ProdList
- 2025
- Advantage
- 58
- Tel
- 010-50973130 17801761073
- Gsiyu@solarbio.com
- Country
- China
- ProdList
- 50751
- Advantage
- 58
- Tel
- 0371-18638163978 18638163978
- 3804817520@qq.com
- Country
- China
- ProdList
- 2642
- Advantage
- 58
- Tel
- 13393721940
- sales@vcommend.com
- Country
- China
- ProdList
- 9963
- Advantage
- 58
- Tel
- 027-88188016 18717196322
- 1764683941@qq.com
- Country
- China
- ProdList
- 6356
- Advantage
- 58
- Tel
- 029-81136151 17392212881
- 1095@dideu.com
- Country
- China
- ProdList
- 10001
- Advantage
- 58
- Tel
- 16621234537
- chenyj@titansci.com
- Country
- China
- ProdList
- 10000
- Advantage
- 58
- Tel
- 021-50706066 15221275939
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 14580
- Advantage
- 58
- Tel
- 020-86211473 13925088720
- linda@aanpharm.com
- Country
- China
- ProdList
- 2944
- Advantage
- 58
- Tel
- 15890142075
- 3555133855@qq.com
- Country
- China
- ProdList
- 9853
- Advantage
- 58
- Tel
- 13000000000
- 497839497@qq.com
- Country
- China
- ProdList
- 882
- Advantage
- 58
- Tel
- +undefined17612118332
- Lucky@hanhonggroup.com
- Country
- China
- ProdList
- 5844
- Advantage
- 58
- Tel
- +86-2759207851; +8618007136271
- hk@fortunachem.com
- Country
- China
- ProdList
- 5990
- Advantage
- 58
- Tel
- +86-057181025280; +8617767106207
- Fax
- 0571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 49734
- Advantage
- 58
- Tel
- 18026280618
- Country
- CHINA
- ProdList
- 187
- Advantage
- 58