ChemicalBook > CAS DataBase List > Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate

Product Name
Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
CAS No.
139481-44-0
Chemical Name
Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
Synonyms
Azilsartan-19;Azilsartan Impurity S;Azilsartan Impurity 31;Azilsartan Impurity 21;Azilsartan Impurity 27;Azilsartan Impurity 76;Azilsartan interMediate;Azilsartan interMediate B;Azilsartan Nitrile Methyl Ester;Azilsartan MedoxoMil InterMediate
CBNumber
CB51009654
Molecular Formula
C25H21N3O3
Formula Weight
411.45
MOL File
139481-44-0.mol
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Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Property

Melting point:
168 °C
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
color 
Off-White to Light Yellow
InChI
InChI=1S/C25H21N3O3/c1-3-31-25-27-22-10-6-9-21(24(29)30-2)23(22)28(25)16-17-11-13-18(14-12-17)20-8-5-4-7-19(20)15-26/h4-14H,3,16H2,1-2H3
InChIKey
KSXLHOFDCDKQLH-UHFFFAOYSA-N
SMILES
C1(OCC)N(CC2=CC=C(C3=CC=CC=C3C#N)C=C2)C2=C(C(OC)=O)C=CC=C2N=1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
M3197
Product name
Methyl 1-[(2'-Cyano-[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
Packaging
25G
Price
$75
Updated
2024/03/01
TCI Chemical
Product number
M3197
Product name
Methyl 1-[(2'-Cyano-[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
Packaging
100G
Price
$227
Updated
2024/03/01
TRC
Product number
C988330
Product name
1-[(2''-Cyano-1,1''-biphenyl-4-yl)methyl]-2-ethoxy-7-benzimidazolecarboxylicAcidMethylEster
Packaging
100g
Price
$595
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0077727
Product name
1H-BENZIMIDAZOLE-7-CARBOXYLIC ACID, 1-[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]-2-ETHOXY-METHYL ESTER
Purity
95.00%
Packaging
10MG
Price
$779.63
Updated
2021/12/16
AK Scientific
Product number
W3051
Product name
Methyl 1-[(2'-Cyano-[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
Packaging
500g
Price
$860
Updated
2021/12/16
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Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Chemical Properties,Usage,Production

Description

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate is a key synthetic intermediate in the synthesis of azilsartan, an angiotensin II.1 (AT1) receptor antagonist used in the treatment of hypertension.

Chemical Properties

Pale Yellow Solid

Uses

Intermediate in the synthesis of angiotensin II receptor antagonist.

Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate manufacturers

Hebei Dangtong Import and export Co LTD
Product
Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate 139481-44-0
Price
US $125.00-90.00/kg
Min. Order
100kg
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-06
Henan Bao Enluo International TradeCo.，LTD
Product
Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate 139481-44-0
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-07-06
Anhui Ruihan Technology Co., Ltd
Product
Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate 139481-44-0
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000tons
Release date
2023-09-06

139481-44-0, Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylateRelated Search:

Methyl 4-cyanobenzoate Kresoxim-methyl Methyl carbamate Benzimidazole Methyl salicylate Methyl benzoate Thiophanate-methyl Methylparaben Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate Methyl anthranilate Methyl formate Tribenuron methyl METSULFURON METHYL Candesartan Candesartan cilexetil Trityl candesartan Ethyl -2-ethoxy-1-[[(2-(1Htetrazol-5-yl)biphenyl-4-yl-) methyl] Methyl

  • 1H-BENZIMIDAZOLE-7-CARBOXYLICACID, 1-[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]-2-ETHOXY-METHYLESTER
  • 1-(2-cyanobiphenyl-4-yl-methyl)- 2-ethoxybenzimidazole-7-carboxylic acid ethyl ester
  • Azilsartan Impurity 31
  • 1-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-, methyl ester
  • Azilsartan-19
  • Azilsartan impurity 20/Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
  • methyl 1-((2'-cyano-[1,1'-biphenyl]
  • Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
  • Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)Methyl)-2-ethoxy-1H-benzo[d]iMidazole-7-carboxylate
  • 1-[(2'-Cyano-1,1'-biphenyl-4-yl)Methyl]-2-ethoxy-7-benziMidazolecarboxylic Acid Methyl Ester
  • 3-[(2'-Cyanobiphenyl-4-yl)Methyl]-2-ethoxy-3H-benziMidazole-4-carboxylic Acid Methyl Ester
  • Methyl 1-[(2'-Cyanobiphenyl-4-yl)Methyl]-2-ethoxybenziMidazole-7-carbo
  • Methyl 1-((2'-cyanobiphenyl-4-yl)Methyl)-2-ethoxy-1H-benzo[d]iMidazole-7-carboxylate
  • IH-BENZIMIDAZOLE-7-CARBOXXYLIC ACID,1-((2'-CYANO(1,1-BIPHENYL)-4-YL)METHYL)-2-ETHOXY-ETHYL ESTER
  • Methyl1-[(2'-cyanobiphenyl-4-yl)Methyl]-2-ethoxy-benziMidazole-7-carboxylate
  • MeEthyl-2-ethoxy-1-[[(2'-cyanobiphenyl-4-yl)Methyl]benziMidazole]-7 -carboxylate
  • Azilsartan MedoxoMil InterMediate
  • Azilsartan interMediate
  • Methyl1-[(2'-cyanobiphenyl-4-yl)Methyl]-2-ethoxy-1H-benziMidazole-7-carboxylat
  • Azilsartan interMediate B
  • 1-[(2'-Cyanobiphenyl-4-yl)Methyl]-2-ethoxy-1H-benzo[d]iMidazole-7-carboxylic acid Methyl ester
  • 3-[[4-(2-cyanophenyl)phenyl]methyl]-2-ethoxy-4-benzimidazolecarboxylic acid methyl ester
  • -cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
  • Candesartan ester intermediate (methyl C6)
  • Azilsartan Impurity 21
  • Azilsartan Impurity 27
  • Azilsartan Impurity S
  • METHYL 1-(2'-CYANOBIPHENYL-4-YL)METHYL-2-ETHOXY BENZIMIDAZOLE-7-CARBOXYLATE(EBC-II)
  • Candesartan (C6) methyl ester intermediates
  • Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate(C6 methylester)
  • Azilsartan Nitrile Methyl Ester
  • Methyl 1-[(2'-Cyanobiphenyl-4-yl) Methyl]-2-Ethoxy-1H-enzimidazole-7-Carboxylate
  • 1-[(2'-Cyano-[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic Acid Methyl Ester
  • CANDESARTAN INTERMEDIATE(METHYL ESTER C6)
  • Azilsartan & Candesartan Cilexetil intermediates
  • Methyl1-[(2’cynobiphenyl-4-yl)\methyl]-2-ethoxybenzimidazole-7-carboxylate
  • Methyl1-[(2'cynobiphenyl-4-yl)\methyl]-2-ethoxybenzimidazole-7-carboxylatedine-3-carboxylate
  • Azilsartan Impurity 76
  • 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
  • Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2- ethoxy-1ethyl)-2-H-benzo[d]imidazole-7-carboxylate
  • ethyl 3-((2'-carbamoyl-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carboxylate
  • Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-Ethoxy-1H-Benzimidazole-7-Carboxylate [CDS-7]
  • Methyl 1-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
  • Methyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-ethoxy-1H-benzodimidazol-7-carboxylate
  • Methyl 2-ethoxy-1-[(2'-cyanobiphenyl-4-yl)-methyl]-1Hbenzimidazole-7-carboxylate
  • Azilsartan Impurity 1 methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl) -2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
  • Methyl 3-((2'-cyanobiphenyl-4-yl) methyl)-2-ethoxy-3H-benzo [d]imidazole-4-carboxylate
  • Methyl 1-[(2'-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
  • Methyl 1-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate
  • Methyl 1-(2'-cyanobiphenyl-4-yl)methyl-2-ethoxy-1H-benzodimidazol-7-carboxylate
  • 139481-44-0
  • 1883681-10-1
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Intermediates
  • Candesartan