ChemicalBook > CAS DataBase List > 4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID

4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID

Product Name
4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID
CAS No.
400-36-2
Chemical Name
4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID
Synonyms
4,4,4-trifluoro-3-oxobutanoic acid;4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID;Butanoic acid, 4,4,4-trifluoro-3-oxo-
CBNumber
CB51010508
Molecular Formula
C4H3F3O3
Formula Weight
156.06
MOL File
400-36-2.mol
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4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID Property

Boiling point:
189.6±40.0 °C(Predicted)
Density 
1.519
storage temp. 
2-8°C
pka
0.83±0.32(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0352125
Product name
4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID
Purity
95.00%
Packaging
5MG
Price
$502.06
Updated
2021/12/16
Chemenu
Product number
CM133272
Product name
4,4,4-trifluoro-3-oxobutanoicacid
Purity
95%
Packaging
1g
Price
$580
Updated
2021/12/16
Crysdot
Product number
CD13013866
Product name
4,4,4-Trifluoro-3-oxobutanoicacid
Purity
95+%
Packaging
1g
Price
$650
Updated
2021/12/16
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4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID Chemical Properties,Usage,Production

Synthesis

2261-53-2

400-36-2

Example 5: Reaction (ReacSO-1) To a 1,2-dichloroethane solution (758 g) of crude 4,4,4-trifluoro-3-oxobutanoyl chloride (ca. 1.29 mol) was added slowly and dropwise over a period of 2 hr. to a dioxane solution (214 g) containing 1.29 mol of water (23.3 g), at -40°C to -20°C. Upon completion of the reaction, the concentration of the enolized form of compound (II-II) in the resulting solution (981 g) was determined to be 19 wt% by 1H NMR analysis (with cyclobutanesulfone as the internal standard), which corresponded to a yield of 92%.

References

[1] Patent: WO2015/4035, 2015, A1. Location in patent: Page/Page column 15

4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID Suppliers

China 11 United States 4 Global 15
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4542
Advantage
58
Nanjing BAM Biomedical Technology Co., Ltd.
Tel
18066080842 13952020641
Fax
025-58912720
Email
bamd@foxmail.com
Country
China
ProdList
759
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55
Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
qqyang@aikonchem.com
Country
China
ProdList
15814
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CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
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Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-81139210 +86-18192627656
Fax
+86-29-88380327
Email
1059@dideu.com
Country
China
ProdList
3588
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58
Bejing Famous Pharmaceutical Technology Co., Ltd.
Tel
15811073878
Email
sales@peking-pharmacy.com
Country
China
ProdList
6297
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58
Jilin Chinese Academy of Sciences-yanshen Technology
Tel
+undefined18143011203
Email
info@chemextension.com
Country
China
ProdList
42056
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58
HANGZHOU LEAP CHEM CO., LTD.
Tel
+86-571-87711850
Email
market18@leapchem.com
Country
China
ProdList
43339
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58
Tractus Company Limited
Tel
--
Fax
--
Email
contact@tractuschem.com
Country
China
ProdList
282
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60
Excel Asia Enterprises Ltd.
Tel
--
Fax
--
Country
China
ProdList
225
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50
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View Lastest Price from 4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID 400-36-2
Price
US $1.00-3.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000KG
Release date
2024-07-24

400-36-2, 4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACIDRelated Search:

METHYL 4,4,4-TRIFLUOROACETOACETATE ETHYL 2-METHYL-4,4,4-TRIFLUOROACETOACETATE Ethyl 2-chloro-4,4,4-trifluoroacetoacetate ISOPROPYL 4,4,4-TRIFLUOROACETOACETATE Ethyl 4,4,4-trifluoroacetoacetate Ethyl 2-(ethoxymethylene)-4,4,4-trifluoroacetoacetate ETHYL 4,4,4-TRIFLUORO-2-(TRIPHENYLPHOSPHORANYLIDENE)ACETOACETATE 4,4,4-TRIFLUORO-ACETOACETIC ACID TERT-BUTYL ESTER 4,4,4-TRIFLUORO-2-HYDROXYLIMINO-3-OXOBUTYRIC ACID ETHYL ESTER ETHYL 4,4,4-TRIFLUORO-2-METHOXY-3-OXOBUTYRATE A-TRIFLUOROACETYL-G-BUTYROLACTONE ETHYL 3-([2-ACETYL-5-(TERT-BUTYL)-3-THIENYL]AMINO)-2-(2,2,2-TRIFLUOROACETYL)ACRYLATE METHYL 4-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)THIOPHENE-3-CARBOXYLATE METHYL 2-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)BENZOATE 4,4,4-TRIFLUORO-3-OXO-2-(PHENYLHYDRAZONO)BUTYRIC ACID ETHYL ESTER METHYL 2-([2-(ETHOXYCARBONYL)-4,4,4-TRIFLUORO-3-OXOBUT-1-ENYL]AMINO)THIOPHENE-3-CARBOXYLATE ETHYL 2-(2,6-DICHLOROBENZYL)-4,4,4-TRIFLUOROACETOACETATE ETHYL TRIFLUOROACETYLBROMOACETATE

  • 4,4,4-TRIFLUORO-3-OXO-BUTYRIC ACID
  • 4,4,4-trifluoro-3-oxobutanoic acid
  • Butanoic acid, 4,4,4-trifluoro-3-oxo-
  • 400-36-2