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Bizelesin

Product Name
Bizelesin
CAS No.
129655-21-6
Chemical Name
Bizelesin
Synonyms
U-77779;Bizelesin;NSC-615291;(8S,8'S)-6,6'-[Carbonylbis(iMino-1H- indole-5,2-diylcarbonyl)]bis[8-(chloroMethyl)-3,6,7,8-tetrahydro-1-Methylbe;1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea;N,N'-Bis[2-[[(1S)-1-(chloroMethyl)-1,6-dihydro-5-hydroxy-8-Methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]urea;Urea, N,N'-bis[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]-;1,3-Bis[2-[[[(8S)-8β-chloromethyl-3,6,7,8-tetrahydro-4-hydroxy-1-methylbenzo[1,2-b:4,3-b']dipyrrol]-6-yl]carbonyl]-1H-indol-5-yl]urea
CBNumber
CB51016702
Molecular Formula
C43H36Cl2N8O5
Formula Weight
815.7
MOL File
129655-21-6.mol
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Bizelesin Property

Density 
1.604±0.06 g/cm3(Predicted)
pka
10.06±0.40(Predicted)
form 
Solid
color 
Off-white to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B591700
Product name
Bizelesin
Packaging
100mg
Price
$35750
Updated
2021/12/16
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Bizelesin Chemical Properties,Usage,Production

Uses

As members of the cyclopropylpyrroloindole family, Adozelesin and Bizelesin cause genomic DNA lesions by alkylating DNA. Adozelesin induces single-strand DNA lesions, whereas Bizelesin induces both si ngle-strand lesions and double-strand DNA cross-links. liferation by different pathways (i.e., Adozelesin induced apoptosis, and Bizelesin induced senescence).

Bizelesin Preparation Products And Raw materials

Raw materials

Preparation Products

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Bizelesin Suppliers

Canada 1 China 17 India 1 United States 1 Global 20
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

129655-21-6, BizelesinRelated Search:

4-Methyl-5-aminoindole Bizelesin 5-AMINOINDOLE HYDROCHLORIDE 7-Hydroxyindole 3-Dimethylamino-2-methylpropyl chloride hydrochloride 5-ACETAMIDOINDOLE

  • 1,3-Bis[2-[[[(8S)-8β-chloromethyl-3,6,7,8-tetrahydro-4-hydroxy-1-methylbenzo[1,2-b:4,3-b']dipyrrol]-6-yl]carbonyl]-1H-indol-5-yl]urea
  • NSC-615291
  • U-77779
  • (8S,8'S)-6,6'-[Carbonylbis(iMino-1H- indole-5,2-diylcarbonyl)]bis[8-(chloroMethyl)-3,6,7,8-tetrahydro-1-Methylbe
  • N,N'-Bis[2-[[(1S)-1-(chloroMethyl)-1,6-dihydro-5-hydroxy-8-Methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]urea
  • Bizelesin
  • 1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea
  • Urea, N,N'-bis[2-[[(1S)-1-(chloromethyl)-1,6-dihydro-5-hydroxy-8-methylbenzo[1,2-b:4,3-b']dipyrrol-3(2H)-yl]carbonyl]-1H-indol-5-yl]-
  • 129655-21-6
  • C43H36Cl2N8O5
  • Chiral Reagents
  • Indole Derivatives
  • Intermediates & Fine Chemicals
  • Pharmaceuticals