3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- Product Name
- 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- CAS No.
- 175277-11-9
- Chemical Name
- 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- Synonyms
- BUTTPARK 52\11-22;TIMTEC-BB SBB010222;3-(tert-Butyl)-5-carboxy-1-methyl-1H-pyrazole;3-TERT-BUTYL-1-METHYLPYRAZOLE-5-CARBOXYLIC ACID;5-tert-butyl-2-methylpyrazole-3-carboxylic acid;3-(T-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID;5-tert-Butyl-2-methyl-2H-pyrazol-3-carboxylic acid;3-(tert-Butyl)-1-methyl-1H-pyrazole-carboxylic acid;5-TERT-BUTYL-2-METHYL-2 H-PYRAZOLE-3-CARBOXYLIC ACID;3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID
- CBNumber
- CB5108464
- Molecular Formula
- C9H14N2O2
- Formula Weight
- 182.22
- MOL File
- 175277-11-9.mol
3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Property
- Melting point:
- 151 °C
- Boiling point:
- 317.7±30.0 °C(Predicted)
- Density
- 1.13
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.15±0.25(Predicted)
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 175277-11-9(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39-37/39
- HazardClass
- IRRITANT
- HS Code
- 2933199090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B423295
- Product name
- 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylicAcid
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FB136162
- Product name
- 3-tert-Butyl-1-methyl-1H-pyrazole-5-carboxylic acid
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 4H21-1-K5
- Product name
- 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid
- Packaging
- 1g
- Price
- $88
- Updated
- 2021/12/16
- Product number
- FB136162
- Product name
- 3-tert-Butyl-1-methyl-1H-pyrazole-5-carboxylic acid
- Packaging
- 1g
- Price
- $128
- Updated
- 2021/12/16
- Product number
- 4H21-1-K5
- Product name
- 3-(tert-Butyl)-1-methyl-1H-pyrazole-5-carboxylic acid
- Packaging
- 5G
- Price
- $152
- Updated
- 2021/12/16
3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
133261-10-6
175277-11-9
General procedure for the synthesis of 1-methyl-3-tert-butylpyrazole-5-carboxylic acid from ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate: 2 M aqueous sodium hydroxide solution (100 mL) was added to ethyl 3-(tert-butyl)-1-methyl-1H-pyrazole-5-carboxylate (185 mmol), and the reaction mixture was heated and refluxed for 2.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature, diluted with 100 mL of water and the pH was adjusted to acidic (about pH 2) with 30% aqueous hydrochloric acid. The precipitated solid was collected by filtration, washed with water and dried at 60 °C for 24 h to afford 1-methyl-3-tert-butylpyrazole-5-carboxylic acid as an off-white solid (27.1 g, 80% yield). [0211] 1H NMR (400 MHz, DMSO-d6) δ: 13.19 (broad peak, 1H), 6.66 (single peak, 1H), 3.99 (single peak, 3H), 1.23 (single peak, 9H). Mass spectrum (m/z): 183 (M + H).
References
[1] Journal of Organic Chemistry, 1997, vol. 62, # 17, p. 5908 - 5919
[2] Patent: WO2009/71706, 2009, A1. Location in patent: Page/Page column 43-44
[3] Patent: US2011/218197, 2011, A1. Location in patent: Page/Page column 44
[4] Patent: US2012/202856, 2012, A1. Location in patent: Page/Page column 22
3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-(TERT-BUTYL)-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID manufacturers
- Product
- 3-tert-Butyl-1-methylpyrazole-5-carboxylic acid 175277-11-9
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%; 99%
- Supply Ability
- 500g;1kg； 25kg
- Release date
- 2020-01-09