AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2

ChemicalBook > CAS DataBase List > AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2

AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2

Product Name: AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2
CAS No.: 475221-20-6
Chemical Name: AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2
Synonyms: NEP1-40;NOGO-66 (1-40);PubChem ID: 90488731;Nogo Extracellular Peptide;M.W. 4625.11 C206H324N56O65;NOGO EXTRACELLULAR PEPTIDE, 1-40;NOGO-66 (1-40) ANTAGONIST PEPTIDE;NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40;AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2;ARG-ILE-TYR-LYS-GLY-VAL-ILE-GLN-ALA-ILE-GLN-LYS-SER-ASP-GLU-GLY-HIS-PRO-PHE-ARG-ALA-TYR-LEU-GLU-SER-GLU-VAL-ALA-ILE-SER-GLU-GLU-LEU-VAL-GLN-LYS-TYR-SER-ASN-SER-NH2
CBNumber: CB5110481
Molecular Formula: C206H324N56O65
Formula Weight: 4625.11
MOL File: 475221-20-6.mol

Less

AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2 Property

storage temp.: -20°C
solubility: H₂O: 1 mg/mL
form: solid
color: white
Water Solubility: Soluble to 1 mg/ml in water

Less

Safety

Safety Statements: 22-24/25
WGK Germany: 3

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N7161
Product name: Nogo-66(1-40) antagonist peptide
Purity: ≥84% (HPLC)
Packaging: 1mg
Price: $231.2
Updated: 2024/03/01

Tocris

Product number: 1984
Product name: Nogo-66(1-40)
Packaging: 1
Price: $374
Updated: 2021/12/16

ApexBio Technology

Product number: B5247
Product name: Nogo-66(1-40)
Packaging: 1mg
Price: $549
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0003973
Product name: NOGO-66(1-40) ANTAGONIST PEPTIDE
Purity: 95.00%
Packaging: 1MG
Price: $859.85
Updated: 2021/12/16

Less

AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2 Chemical Properties,Usage,Production

Uses

Nogo-66(1-40) antagonist peptide has been used as a Nogo-66 receptor antagonist peptide:

to study the preliminary therapeutic effect after inhibition of Nogo-A in the cauda equina compression (CEC) model
to determine the effects of Nogo-A/NgR1 on autophagic activation
to study its role in Nogo-B mediated axonal branching using Schwann cells and sensory neurons of mice

Biochem/physiol Actions

Myelin-derived axon outgrowth inhibitors, such as Nogo, may account for the lack of axonal regeneration in the central nervous system (CNS) after trauma in adult mammals. Nogo-66 can inhibit axonal outgrowth through an axonal Nogo-66 receptor (NgR). Competitive antagonists of NgR derived from amino-terminal peptide fragments of Nogo-66. The Nogo-66(1 40) antagonist peptide (NEP1 40) blocks Nogo-66 or CNS myelin inhibition of axonal outgrowth in vitro, demonstrating that NgR mediates a significant portion of axonal outgrowth inhibition by myelin. Intrathecal administration of NEP1 40 to rats with mid-thoracic spinal cord hemisection results in significant axon growth of the corticospinal tract, and improves functional recovery. Thus, Nogo-66 and NgR have central roles in limiting axonal regeneration after CNS injury, and NEP1-40 provides a potential therapeutic agent.

storage

Store at -20°C

AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

Less

AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2 Suppliers

China 48 Europe 1 Germany 2 Switzerland 1 United Kingdom 1 United States 6 USA 1 Global 60

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7269
Advantage: 58

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303 +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4840
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Fax: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 6756
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30240
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: wulan@absin.cn
Country: China
ProdList: 24731
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14081
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 0571-88211921 13355716090
Email: Sales@gotopbio.com
Country: China
ProdList: 2859
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Nanjing Yuanpeptide Biotech Co.，Ltd.

Tel: 18168071971
Email: support@yuan-peptide.com
Country: China
ProdList: 2979
Advantage: 58

Shaoxing Junyu Biotechnology Co., LTD

Tel: 0571-88211921 15572296305
Email: sales4@gotopbio.com
Country: China
ProdList: 5128
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24647
Advantage: 58

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6445
Advantage: 58

Hangzhou Baige Pharmaceutical Technology Co. , Ltd.

Tel: 0571-85350119 15888826472
Email: 15888826472@163.com
Country: China
ProdList: 2729
Advantage: 58

Shanghai HongTide Biotechnology Co.,Ltd.

Tel: 19961912513
Email: sales@hongtide.com
Country: China
ProdList: 4597
Advantage: 58

Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd

Tel: 18014456767
Email: wenxi@jszkhy.com
Country: China
ProdList: 1350
Advantage: 58

Combio (Suzhou) Ltd.

Tel: 0512-51886999 17706251929
Email: office@combiosz.com
Country: China
ProdList: 2981
Advantage: 58

Zhejiang Jiekun Biotechnology Co., Ltd

Tel: 0571-88211951 13735575465
Email: sales1@gotopbio.com
Country: China
ProdList: 4904
Advantage: 58

Taiyuan Bailihengkang Biotechnology Co., Ltd

Tel: 19135651983 19135651983
Email: 18611134419@163.com
Country: China
ProdList: 4416
Advantage: 58

Hangzhou Beiputai Biopharmaceutical Co., Ltd

Tel: 0571-85350119 13305819357
Email: bptsales@163.com
Country: China
ProdList: 3849
Advantage: 58

Changsha MOL Changes Biotechnology Co., Ltd.

Tel: +8619375158599
Email: info@molchanges.com
Country: China
ProdList: 5225
Advantage: 58

Shenzhen Nexconn Pharmatechs Ltd

Tel: +86-755-89396905 +86-15013857715
Email: admin@nexconn.com
Country: China
ProdList: 10310
Advantage: 58

Zhejiang Hangyu API Co., Ltd

Tel: +8617531972939
Email: anna@api-made.com
Country: China
ProdList: 2943
Advantage: 58

LEAPCHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 43340
Advantage: 58

Hebei Miaoyin Technology Co.,Ltd

Tel: +86-17367732028 +86-17367732028
Email: kathy@hbyinsheng.com
Country: China
ProdList: 3512
Advantage: 58

Nanjing Doge Biomedical Technology Co., Ltd

Tel: +86-25-58227606 +86-15305155328
Email: sales@dogechemical.com
Country: China
ProdList: 4128
Advantage: 58

Beijing Bolide Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1985563437@qq.com
Country: CHINA
ProdList: 6158
Advantage: 58

Shanghai Chaoyan Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 471161314@qq.com
Country: CHINA
ProdList: 6210
Advantage: 58

Shanghai Yanmu Industrial Co., Ltd.

Tel: --
Fax: --
Email: 2095001174@qq.com
Country: CHINA
ProdList: 6722
Advantage: 58

Shanghai Guduo Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6266
Advantage: 58

Shanghai Yihui Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: yihbio@163.com
Country: CHINA
ProdList: 5667
Advantage: 58

Shanghai Gantu Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 1920192055@qq.com
Country: CHINA
ProdList: 1843
Advantage: 58

BEIJING BIOSYNTHESIS BIOTECHNOLOGY CO., LTD.

Tel: --
Fax: --
Email: sales@bioss.com.cn
Country: CHINA
ProdList: 6717
Advantage: 58

Beijing Taize Jiaye Technology Development Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6050
Advantage: 58

Shanghai Yansheng Industrial Co., Ltd.

Tel: --
Fax: --
Email: shyssw@126.com
Country: CHINA
ProdList: 6729
Advantage: 58

Shanghai Guyan Industrial Co., Ltd.

Tel: --
Fax: --
Email: 3004901493@qq.com
Country: CHINA
ProdList: 6817
Advantage: 58

Beijing Taize Ruida Technology Co., Ltd.

Tel: --
Fax: --
Email: taizeorder@163.com
Country: CHINA
ProdList: 6536
Advantage: 58

Shanghai Fusheng Industrial Co., Ltd.

Tel: --
Fax: --
Email: 1822382616@qq.com
Country: CHINA
ProdList: 6517
Advantage: 58

Shanghai Haoyang Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: 596799915@QQ.COM
Country: CHINA
ProdList: 2905
Advantage: 58

Shanghai Weiwei Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: sales@wheybio.com
Country: CHINA
ProdList: 4398
Advantage: 58

Shanghai Hao Test Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: prbiological@sohu.com
Country: CHINA
ProdList: 6846
Advantage: 58

Shanghai Bangjing Industrial Co., Ltd.

Tel: --
Fax: --
Email: 3004972055@qq.com
Country: CHINA
ProdList: 6538
Advantage: 58

Beijing Fubo Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: info@f-biology.com
Country: CHINA
ProdList: 6025
Advantage: 58

Shanghai Huzhen Industrial Co., Ltd.

Tel: --
Fax: --
Email: shhzsw01@163.com
Country: CHINA
ProdList: 6478
Advantage: 58

475221-20-6, AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2Related Search:

AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2

ARG-ILE-TYR-LYS-GLY-VAL-ILE-GLN-ALA-ILE-GLN-LYS-SER-ASP-GLU-GLY-HIS-PRO-PHE-ARG-ALA-TYR-LEU-GLU-SER-GLU-VAL-ALA-ILE-SER-GLU-GLU-LEU-VAL-GLN-LYS-TYR-SER-ASN-SER-NH2

AC-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH2

M.W. 4625.11 C206H324N56O65

NEP1-40

NOGO-66 (1-40)

NOGO-66 (1-40) ANTAGONIST PEPTIDE

NOGO EXTRACELLULAR PEPTIDE, 1-40

PubChem ID: 90488731

NEP1-40; NOGO EXTRACELLULAR PEPTIDE; 1-40

Nogo Extracellular Peptide

L-Serinamide,n2-acetyl-L-arginyl-L-isoleucyl-L-tyrosyl-L-Lysylglycyl-L-valyl-L-isoleucyl-L-glutaminyl-L-alanyl-L-isoleucyl-L-glutaminyl-L-Lysyl-L-seryl-L-a-aspartyl-L-a-glutamylglycyl-l-histidyl-l-pro

Arg-Ile-Tyr-Lys-Gly-Val-Ile-Gln-Ala-Ile-Gln-Lys-Ser-Asp-Glu-Gly-His-Pro-Phe-Arg-Ala-Tyr-Leu-Glu-Ser-Glu-Val-Ala-Ile-Ser-Glu-Glu-Leu-Val-Gln-Lys-Tyr-Ser-Asn-Ser-NH2

475221-20-6

C206H324N56O65

Various Peptides