ChemicalBook > CAS DataBase List > Talampicillin hydrochloride

Talampicillin hydrochloride

Product Name
Talampicillin hydrochloride
CAS No.
39878-70-1
Chemical Name
Talampicillin hydrochloride
Synonyms
Talat;PC 183;Talpen;BRL 8988;Yamacillin;Aseocillin;Ampicillin Impurity 26;D-Talampicillin hydrochloride;Talampicillin hydrochloride CRS;Ampicillinphthalidyl hydrochloride
CBNumber
CB51105387
Molecular Formula
C24H23N3O6S.ClH
Formula Weight
517.988
MOL File
39878-70-1.mol
More
Less

Talampicillin hydrochloride Property

Melting point:
154-157° (dec)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T0010000
Product name
Talampicillin hydrochloride
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
t0010000
Price
$150
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
API0016125
Product name
TALAMPICILLIN HYDROCHLORIDE
Purity
95.00%
Packaging
10MG
Price
$280.35
Updated
2021/12/16
More
Less

Talampicillin hydrochloride Chemical Properties,Usage,Production

Description

Talampicillin was synthesized by Yamanouchi Pharmaceutical Co. in 1971 by esterifying the carboxylic acid group of ampicillin in order to improve the oral absorption. When administered orally, it is hydrolyzed to ampicillin by intestinal esterase. Its bioavailability is two or more times as high as that of ampicillin, and it is used to treat the same infections as those for which ampicillin is used orally but in doses only half or one-third as large.

Originator

Talpen,Beecham,US,1975

Manufacturing Process

A fine suspension of 25.18 grams (0.05 mol) of potassium salt of enamine protected ampicillin and 10.65 grams (0.05 mol) 3-bromophthalide were reacted in a 1:2 mixture of acetone/ethyl acetate (1,500 ml) for 24 hours. After filtration the organic layer was washed twice with 250 ml portions of 1 N sodium bicarbonate and brine, dried over anhydrous magnesium sulfate and concentrated in vacuo. Addition of ether crystallized the phthalide enamine protected α-aminophenylacetamido penicillanate in 85% yield.

Therapeutic Function

Antibacterial

Talampicillin hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Talampicillin hydrochloride Suppliers

Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
Nanjing wangzhixing Pharmaceutical Technology Co., Ltd
Tel
15850510341
Fax
025-85722793
Email
shiqingran@wzxchem.com
Country
China
ProdList
3746
Advantage
58
QUALITY CONTROL SOLUTIONS LTD.
Tel
0755-66853366; 13670046396
Email
ORDERS@QCSRM.COM
Country
China
ProdList
24342
Advantage
58
Hubei Moco Chemical Co., Ltd.
Tel
18627753421 18627756402
Fax
QQ:3001051413
Email
3001009495@qq.com
Country
China
ProdList
19063
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58

39878-70-1, Talampicillin hydrochlorideRelated Search:


  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-aminophenylacetyl]amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, monohydrochloride, (2S,5R,6R)- (9CI)
  • Ampicillin phthalidyl ester hydrochloride
  • D-Talampicillin hydrochloride
  • PC 183
  • Talat
  • Talpen
  • Yamacillin
  • Ampicillinphthalidyl hydrochloride
  • Aseocillin
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester, monohydrochloride, [2S-[2a,5a,6b(S*)]]-
  • Talampicillin hydrochloride CRS
  • Ampicillin Impurity 26
  • BRL 8988
  • 39878-70-1
  • C24H23N3O6SHCl
  • C24H23N3O6SClH