ChemicalBook > CAS DataBase List > (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product Name
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
CAS No.
114676-69-6
Chemical Name
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
Synonyms
(2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;Boc-cis-4-Hydroxy-D-proline methyl ester;1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate;Boc-Cis-D-Hyp-OMe;cis-Boc-d-Hyp-Ome;N-Boc-cis-D-Hyp-Ome;(2R,4R)-1-Boc-4-hydroxypyrroL;CIS-1-BOC-4-HYDROXY-D-PROLINATE;(Tert-Butoxy)Carbonyl D-cis-Hyp-OMe;Methyl cis-Boc-4-hydroxy-D-prolinate
CBNumber
CB51118684
Molecular Formula
C11H19NO5
Formula Weight
245.27
MOL File
114676-69-6.mol
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(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Property

Melting point:
76 °C
Boiling point:
335.2±42.0 °C(Predicted)
alpha 
63° (C=1,EtOH)
Density 
1.216±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
form 
Powder
pka
14.27±0.40(Predicted)
color 
White
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5857
Product name
N-(tert-Butoxycarbonyl)-cis-4-hydroxy-D-proline Methyl Ester
Purity
>97.0%(GC)
Packaging
1g
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
B5857
Product name
N-(tert-Butoxycarbonyl)-cis-4-hydroxy-D-proline Methyl Ester
Purity
>97.0%(GC)
Packaging
5g
Price
$43
Updated
2024/03/01
Alfa Aesar
Product number
H63136
Product name
N-Boc-cis-4-hydroxy-D-proline methyl ester, 95%
Packaging
1g
Price
$62.65
Updated
2024/03/01
Alfa Aesar
Product number
H63136
Product name
N-Boc-cis-4-hydroxy-D-proline methyl ester, 95%
Packaging
5g
Price
$243.65
Updated
2024/03/01
Alfa Aesar
Product number
H63136
Product name
N-Boc-cis-4-hydroxy-D-proline methyl ester, 95%
Packaging
250mg
Price
$21.4
Updated
2021/12/16
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(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Chemical Properties,Usage,Production

Uses

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (N-Boc-cis-4-hydroxy-D-proline methyl ester) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Suppliers

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View Lastest Price from (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate manufacturers

Qingdao RENAS Polymer Material Co., Ltd.
Product
N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester 114676-69-6
Price
US $0.00/kg
Min. Order
20kg
Purity
99%
Supply Ability
20 tons
Release date
2024-11-01
Career Henan Chemical Co
Product
METHYL CIS-1-BOC-4-HYDROXY-D-PROLINATE 114676-69-6
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
97-99%
Supply Ability
1000KGS
Release date
2019-12-19

114676-69-6, (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate Related Search:

(1s,3s)-methyl 3-aminocyclobutane carboxylate hydrochloride tert-butyl (cis-3-aminocy... cis-cyclopentane-1,2-diamine dihydrochloride cis-2-(Ethoxycarbonyl)cyclopropanecarboxylic acid cis-cyclopropanecarboxylic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester (+)-CIS-(2R,3S)-3-Hydroxyproline (2S,3R)-3-Hydroxyproline Cis-4-Cyclohexylcyclohexanol (2S,3R)-methyl 3-hydroxypyrrolidine-2-carboxylate hydrochloride (1S,2S)-2-fluorocyclopropanecarboxylic acid cis-3-Hydroxycyclobutanecarboxylic acid rel-(4aR,7aR)-6-Benzyloctahydro-1H-pyrrolo[3,4-b]pyridine CIS-DICHLOROBIS(2,2'-BIPYRIDINE)RUTHENIUM (II) DIHYDRATE, 99 Cyclopropanecarboxylicacid,2-amino-,cis-(9CI) cis-4-Hydroxy-D-proline (S)-(+)-2-(METHOXYMETHYL)PYRROLIDINE (2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate BOC-N-methyl-D-alanine

  • (2R,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylicacid 1-(1,1-dimethylethyl) 2-methyl ester
  • (2R,4R)-1-tert-butyl 2-Methyl 4-hydroxypyrrolidine-1,2-dicarboxy
  • (2R,4R)-1-tert-butyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate
  • Boc-Cis-D-Hyp-OMe
  • Methy cis-1-Boc-4-hydroxy-D-prolinate
  • Methyl cis-Boc-4-hydroxy-D-prolinate
  • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2R,4R)-
  • 1-tert-butyl 2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • N-tert-Butoxycarbonyl-cis-4-hydroxy-D-proline methyl ester
  • Methyl cis-1-Boc-4-hydroxy-D-prolinate
  • (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
  • N-Boc-cis-4-hydroxy-D-proline methyl ester
  • Boc-cis-4-Hydroxy-D-proline methyl ester
  • (Tert-Butoxy)Carbonyl D-cis-Hyp-OMe
  • CIS-1-BOC-4-HYDROXY-D-PROLINATE
  • Methyl (2R,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylate
  • (2R,4R)-N-Boc-4-hydroxyproline methyl ester
  • (2R,4R)-N-Boc-cis-4-hydroxy-D-proline methyl ester
  • N-Boc-cis-D-Hyp-Ome
  • (2R,4R)-1-Boc-4-hydroxypyrroL
  • N-Boc-cis-4-hydroxy-D-prolinemethylester,95%
  • (2R,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester
  • METHYL CIS-1-BOC-4-HYDROXY-D-PROLINATE USP/EP/BP
  • O1-tert-Butyl O2-methyl (2R,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • cis-Boc-d-Hyp-Ome
  • 1-(1,1-Dimethylethyl) 2-methyl (2R,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
  • BOC cis D hydroxyproline methyl ester
  • 114676-69-6