1,2-DIAMINO-4,5-DIFLUOROBENZENE
Application- Product Name
- 1,2-DIAMINO-4,5-DIFLUOROBENZENE
- CAS No.
- 76179-40-3
- Chemical Name
- 1,2-DIAMINO-4,5-DIFLUOROBENZENE
- Synonyms
- 4,5-Difluorobenzene-1,2-diamine;1,2-Diamino-4,5-difluorobenzene;EA358;4,5-Difluoro-2-PhenylenediaMin;4,5-Difluoro-o-phenylenediamine;4,5-Difluoro-1,2-benzenediamine;2-AMINO-4,5-DIFLUOROPHENYLAMINE;4,5-Difluoro-2-PhenylenediaMine;4,5-Difluorophenylene-1,2-diamine;1,2-Benzenediamine, 4,5-difluoro-
- CBNumber
- CB51119494
- Molecular Formula
- C6H6F2N2
- Formula Weight
- 144.12
- MOL File
- 76179-40-3.mol
1,2-DIAMINO-4,5-DIFLUOROBENZENE Property
- Melting point:
- 132 °C
- Boiling point:
- 282.2±35.0 °C(Predicted)
- Density
- 1.407±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder to crystal
- pka
- 3.51±0.10(Predicted)
- color
- White to Brown
- InChI
- InChI=1S/C6H6F2N2/c7-3-1-5(9)6(10)2-4(3)8/h1-2H,9-10H2
- InChIKey
- PPWRHKISAQTCCG-UHFFFAOYSA-N
- SMILES
- C1(N)=CC(F)=C(F)C=C1N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- D3729
- Product name
- 4,5-Difluoro-1,2-phenylenediamine
- Purity
- >97.0%(GC)(T)
- Packaging
- 1g
- Price
- $20
- Updated
- 2025/07/31
- Product number
- D415120
- Product name
- 1,2-Diamino-4,5-difluorobenzene
- Packaging
- 25g
- Price
- $385
- Updated
- 2021/12/16
- Product number
- 3630-3-42
- Product name
- 1,2-Diamino-4,5-difluorobenzene
- Packaging
- 25g
- Price
- $395
- Updated
- 2021/12/16
- Product number
- 044954
- Product name
- 1,2-Diamino-4,5-difluorobenzene
- Purity
- 98%
- Packaging
- 100g
- Price
- $345
- Updated
- 2021/12/16
- Product number
- J94199
- Product name
- 1,2-Diamino-4,5-difluorobenzene
- Packaging
- 100g
- Price
- $350
- Updated
- 2021/12/16
1,2-DIAMINO-4,5-DIFLUOROBENZENE Chemical Properties,Usage,Production
Application
4,5-Difluorobenzene-1,2-diamine is an organic synthesis intermediate and a chemical and pharmaceutical intermediate, which can be used in the research and development of organic synthesis reactions in laboratories and in the research and development of chemical and pharmaceutical products.
Chemical Properties
White powder
Synthesis
78056-39-0
76179-40-3
General procedure for the synthesis of 4,5-difluorophthalimide from 2-nitro-4,5-difluoroaniline: 4,5-difluoro-2-nitroaniline (10 g, 57 mmol) was co-suspended in methanol (150 mL) with 10% palladium carbon catalyst (2.0 g, 1.9 mmol). The reaction system was transferred to a hydrogenation unit and the catalytic hydrogenation reaction was carried out under 50 psi hydrogen pressure. After 3 hours of reaction, the catalyst was removed by filtration through a diatomaceous earth pad and the filtrate was concentrated under reduced pressure to give a solid product. The resulting solid was dried under vacuum at room temperature overnight to obtain white crystalline 4,5-difluorophthalimide (8.05 g, 98% yield).
References
[1] Journal of Medicinal Chemistry, 1993, vol. 36, # 3, p. 331 - 342
[2] Patent: US2005/43292, 2005, A1. Location in patent: Page/Page column 14
[3] Patent: EP2766359, 2016, B1. Location in patent: Paragraph 0755
[4] Journal of Medicinal Chemistry, 1997, vol. 40, # 5, p. 811 - 818
[5] Russian Journal of Organic Chemistry, 2001, vol. 37, # 4, p. 564 - 569
1,2-DIAMINO-4,5-DIFLUOROBENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,2-DIAMINO-4,5-DIFLUOROBENZENE manufacturers
- Product
- 1,2-Diamino-4,5-difluorobenzene 76179-40-3
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-08
- Product
- 1,2-DIAMINO-4,5-DIFLUOROBENZENE 76179-40-3
- Price
- US $55.00-550.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-11-07
- Product
- 1,2-DIAMINO-4,5-DIFLUOROBENZENE 76179-40-3
- Price
- US $50.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-22