Dichloroacetic acid methyl ester

Product Name: Dichloroacetic acid methyl ester
CAS No.: 116-54-1
Chemical Name: Dichloroacetic acid methyl ester
Synonyms: METHYL DICHLOROACETATE;NSC 2882;TwoMethyl chloroacetate;methyldichloroethanoate;methyl2,2-dichloroacetate;Dichloroacetic acid methyl;Methyl Dichloroacetate >Methyl dichloroacetate,purum;METHYL DICHLOROACETATE, 99+%;dichloro-aceticacimethylester
CBNumber: CB5115244
Molecular Formula: C3H4Cl2O2
Formula Weight: 142.97
MOL File: 116-54-1.mol

More

Less

Dichloroacetic acid methyl ester Property

Melting point:: -52 °C (lit.)
Boiling point:: 143 °C (lit.)
Density: 1.381 g/mL at 25 °C (lit.)
refractive index: n20/D 1.442(lit.)
Flash point:: 176 °F
storage temp.: room temp
solubility: 4g/l
form: Liquid
color: Clear colorless
PH: 3.8 (4g/l, H2O, 20℃)
Water Solubility: Slightly soluble
BRN: 1747542
CAS DataBase Reference: 116-54-1(CAS DataBase Reference)
NIST Chemistry Reference: Acetic acid, dichloro-, methyl ester(116-54-1)
EPA Substance Registry System: Acetic acid, 2,2-dichloro-, methyl ester (116-54-1)

More

Less

Safety

Hazard Codes: Xn,Xi,F
Risk Statements: 20-36/37/38-40-38-11
Safety Statements: 26-36-37/39-16-24-9
RIDADR: UN 2299 6.1/PG 3
WGK Germany: 3
RTECS: AG6625000
TSCA: Yes
HazardClass: 6.1(b)
PackingGroup: III
HS Code: 29154000

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 35840
Product name: Methyl dichloroacetate
Purity: ≥99%
Packaging: 500ml
Price: $100
Updated: 2025/07/31

TCI Chemical

Product number: D0309
Product name: Methyl Dichloroacetate
Purity: >99.0%(GC)
Packaging: 25g
Price: $17
Updated: 2025/07/31

TCI Chemical

Product number: D0309
Product name: Methyl Dichloroacetate
Purity: >99.0%(GC)
Packaging: 500g
Price: $57
Updated: 2025/07/31

Sigma-Aldrich

Product number: 36547
Product name: Methyl dichloroacetate
Purity: PESTANAL?, analytical standard
Packaging: 100mg
Price: $30
Updated: 2022/05/15

TRC

Product number: D432005
Product name: DichloroaceticAcidMethylEster
Packaging: 5g
Price: $85
Updated: 2021/12/16

More

Less

Dichloroacetic acid methyl ester Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

Organic intermediate.

Uses

Dichloroacetic Acid Methyl Ester is used in the preparation of telechelics and block copolymers through living radical polymerization.

Uses

Methyl dichloroacetate may be used:

in the diastereoselctive synthesis of bicyclic chlorocyclopropane
as difunctional initiator during atom transfer radical polymerization of methyl or n-butyl acrylate
as reagent during CrCl₂-induced olefination of aldehydes

Synthesis Reference(s)

Journal of the American Chemical Society, 90, p. 5307, 1968 DOI: 10.1021/ja01021a065
The Journal of Organic Chemistry, 28, p. 1133, 1963

General Description

A colorless liquid with an ethereal odor. Combustible. Flash point 176°F. Corrosive to metals and tissue. Used to make other chemicals.

Air & Water Reactions

Decomposed by water to dichloroacetic acid, a corrosive material with evolution of heat [USCG, 1999].

Reactivity Profile

Dichloroacetic acid methyl ester produces toxic fumes of phosgene and HCl when heated [USCG, 1999].

Hazard

Strong irritant to tissue. Forms corrosiveproducts on hydrolysis, keep dry.

Health Hazard

Extremely destructive to the eyes, nose, throat, and upper respiratory tract. May be fatal as a result of spasm, inflammation and edema of the larynx and bronchi, chemical pneumonitis, and pulmonary edema. Symptoms of exposure include burning sensation, coughing, wheezing, laryngitis, shortness of breath, headache, nausea, and vomiting.

Fire Hazard

Special Hazards of Combustion Products: Produces toxic fumes of phosgene and HCl.

Safety Profile

Poisonous irritant to the skin, eyes, and mucous membranes. Hydrolyzes upon contact with moisture to form a product corrosive to tissue. See also DICHLOROACETIC ACID and ESTERS. Dangerous; when heated to decomposition it emits hghly toxic fumes of phosgene and Cl-.

Dichloroacetic acid methyl ester Preparation Products And Raw materials

Raw materials

Chloroacetic acid Trap Dichloroacetic acid Methanol Sulfuric acid

Preparation Products

Thiamphenicol Chloroacetic acid Chloramphenicol Creatinine

More

Less

Dichloroacetic acid methyl ester Suppliers

Americas 1 Belgium 1 China 185 Europe 3 Germany 6 India 14 Japan 4 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 6 United States 28 Global 252

HBCChem, Inc.

Tel: +1-510-219-6317
Fax: +1-650-486-1361
Email: sales@hbcchem.com
Country: United States
ProdList: 10648
Advantage: 60

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

AmChemteq, Inc. (ACI)

Tel: --
Fax: --
Email: info@amchemteq.com
Country: United States
ProdList: 42
Advantage: 58

Oakwood Products, Inc.

Tel: --
Fax: --
Email: sales@oakwoodchemical.com
Country: United States
ProdList: 6193
Advantage: 74

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

TCI America

Tel: --
Fax: --
Email: sales@tciamerica.com
Country: United States
ProdList: 6909
Advantage: 75

Matrix Scientific

Tel: --
Fax: --
Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
Advantage: 80

AccuStandard Inc

Tel: --
Fax: --
Email: info@bester.nl
Country: United States
ProdList: 5300
Advantage: 76

Santa Cruz Biotechnology, Inc.

Tel: --
Fax: --
Email: scbt@scbt.com
Country: United States
ProdList: 3597
Advantage: 60

HBCChem Inc.

Tel: --
Fax: --
Email: sales@hbcchem-inc.com
Country: United States
ProdList: 4569
Advantage: 30

Sisco Research Laboratories Pvt. Ltd.

Tel: --
Fax: --
Email: srlmarketing@dishnetdsl.net
Country: United States
ProdList: 1905
Advantage: 64

Waterstone Technology, LLC

Tel: --
Fax: --
Email: sales@waterstonetech.com
Country: United States
ProdList: 6786
Advantage: 30

ChemService Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6379
Advantage: 68

Ryan Scientific, Inc.

Tel: --
Fax: --
Email: ryan.reichlyn@ryansci.com
Country: United States
ProdList: 6439
Advantage: 60

Narchem Corporation

Tel: --
Fax: --
Email: sales@narchem.com
Country: United States
ProdList: 2813
Advantage: 60

2A PharmaChem USA

Tel: --
Fax: --
Email: sales@2apharmachem.com
Country: United States
ProdList: 6137
Advantage: 39

City Chemical LLC

Tel: --
Fax: --
Email: sales@citychemical.com
Country: United States
ProdList: 6708
Advantage: 72

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

AK Scientific, Inc.

Tel: --
Fax: --
Email: sales@aksci.com
Country: United States
ProdList: 6347
Advantage: 65

Acros Organics USA

Tel: --
Fax: --
Email: eveleth@fisherchem.com
Country: United States
ProdList: 3846
Advantage: 81

Crescent Chemical Co., Inc.

Tel: --
Fax: --
Email: sales@creschem.com
Country: United States
ProdList: 4597
Advantage: 68

MP Biomedicals, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6561
Advantage: 81

City Chemicals Corporation

Tel: --
Fax: --
Country: United States
ProdList: 6460
Advantage: 72

Eastern Chemical Corp.

Tel: --
Fax: --
Email: eastern@u-g.com
Country: United States
ProdList: 2786
Advantage: 34

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: United States
ProdList: 6814
Advantage: 81

ChemPacific Corporation

Tel: --
Fax: --
Email: sales@chempacific.com
Country: United States
ProdList: 6891
Advantage: 51

Pfaltz & Bauer, Inc.

Tel: --
Fax: --
Email: sales@pfaltzandbauer.com
Country: United States
ProdList: 6828
Advantage: 72

More

Less

View Lastest Price from Dichloroacetic acid methyl ester manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: Dichloroacetic acid methyl ester 116-54-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: Dichloroacetic acid methyl ester 116-54-1
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 100kg
Release date: 2020-01-07

116-54-1, Dichloroacetic acid methyl esterRelated Search:

DICHLOROACETIC ANHYDRIDE DICHLOROMETHOXYACETIC ACID METHYL ESTER DALAPON-METHYL ESTER Dichloroacetic acid methyl ester Ethyl trichloroacetate ETHYL DICHLOROACETATE DIISOPROPYL DICHLOROMALONATE Vinyl trichloroacetate ERBON TRICHLOROACETIC ANHYDRIDE Methyl trichloroacetate Chloroacetic acid Methyl acetate Methyl chloroacetate Dichloroacetic acid TRICHLOROACETIC ACID LAURYL ESTER(C12) PENTACHLOROPHENYL DICHLOROACETATE TRICHLOROACETIC ACID OCTYL ESTER(C8)

Methyl dichloroacetate solution

1,1-Dichloro-2-methoxy-2-oxoethane

Dichloroacetic acid methyl

Methyl dichloroacetate, synthesis grade

Methyl dichloroacetate,purum

TwoMethyl chloroacetate

dichloro-aceticacimethylester

ethanoicacid,dichloro-,methylester

methyl2,2-dichloroacetate

methyldichloroethanoate

METHYL DICHLOROACETATE

DIMETHOXYACETIC ACID METHYL ESTER

DICHLOROACETIC ACID METHYL ESTER

NSC 2882

METHYL DICHLOROACETATE PESTANAL

METHYL DICHLOROACETATE, 99+%

METHYL DICHLOROACETATE extrapure

METHYL DICHLOROACETATE, 1000MG, NEAT

Aceticacid,dichloro-,methylester

Methyl Dichloroacetate &gt

Acetic acid, 2,2-dichloro-, methyl ester

Dichloroacetic acid methyl ester ISO 9001：2015 REACH

YA12320200MB DichloroacetiCacid-methyLester 10

Dichloroacetic acid-methyl ester 1000 μg/mL in Methyl-tert-butyl ether

116-54-1

16-54-1

Cl2CHCO2CH3

Cl2CHCOOCH3

Cl2CHOOCH3

Organic Building Blocks

Esters

Building Blocks

Carbonyl Compounds

C2 to C5

Alpha sort

Pharmaceutical Intermediates

500 Series Drinking Water Methods

EPA

Method 552

H-MAlphabetic

M

META - METH

Pesticides&Metabolites

Pyrans

C2 to C5

Carbonyl Compounds

Esters

bc0001