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Methyl trichloroacetate

Product Name
Methyl trichloroacetate
CAS No.
598-99-2
Chemical Name
Methyl trichloroacetate
Synonyms
oroacetate;TCA-Methyl est;TCA-METHYL ESTER;RARECHEM AL BF 1451;Piracetam Impurity 9;Methyl trichlroracetate;METHYL TRICHLOROACETATE;Methyltrichloroacetate,99%;methyl trichloroacetic acid;methyl 2,2,2-trichloroacetate
CBNumber
CB7276383
Molecular Formula
C3H3Cl3O2
Formula Weight
177.41
MOL File
598-99-2.mol
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Methyl trichloroacetate Property

Melting point:
-18°C
Boiling point:
152-153 °C (lit.)
Density 
1.488 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.455(lit.)
Flash point:
163 °F
storage temp. 
room temp
solubility 
1050mg/l
form 
clear liquid
color 
Colorless to Almost colorless
Water Solubility 
Insoluble in water
BRN 
1756075
Dielectric constant
8.7899999999999991
LogP
2.03
CAS DataBase Reference
598-99-2(CAS DataBase Reference)
NIST Chemistry Reference
Acetic acid, trichloro-, methyl ester(598-99-2)
EPA Substance Registry System
Acetic acid, 2,2,2-trichloro-, methyl ester (598-99-2)
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Safety

Hazard Codes 
Xi,F
Risk Statements 
36/37/38-40-38-11
Safety Statements 
26-36-16-24-9
RIDADR 
UN 2533 6.1/PG 3
WGK Germany 
3
RTECS 
AJ8380000
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29154000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
242497
Product name
Methyl trichloroacetate
Purity
99%
Packaging
25g
Price
$63.2
Updated
2023/06/20
TCI Chemical
Product number
T1013
Product name
Methyl Trichloroacetate
Purity
>96.0%(GC)
Packaging
25g
Price
$40
Updated
2024/03/01
TCI Chemical
Product number
T1013
Product name
Methyl Trichloroacetate
Purity
>96.0%(GC)
Packaging
500g
Price
$364
Updated
2024/03/01
AK Scientific
Product number
7013AF
Product name
Methyl trichloroacetate
Packaging
500g
Price
$479
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0037245
Product name
METHYL TRICHLOROACETATE
Purity
95.00%
Packaging
25G
Price
$1119.97
Updated
2021/12/16
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Methyl trichloroacetate Chemical Properties,Usage,Production

Chemical Properties

Colorless clear liquid

Uses

Methyl trichloroacetate was used for negative staining of protein that allowed unmodified proteins to be recovered for biological studies or transblot for amino acid sequence.

Reactions

methyl trichloroacetate reacts with sodium methoxide then the formed product is carbine.

Synthesis Reference(s)

Tetrahedron Letters, 20, p. 3643, 1979 DOI: 10.1016/S0040-4039(01)95485-1

General Description

Methyl trichloroacetate appears as a colorless liquid. Insoluble in water and denser than water. Contact may slightly irritate skin, eyes and mucous membranes. May be toxic by ingestion. Used to make other chemicals.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A halogenated ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. A mixture of the ester and trimethylamine reacted violently. Polymerization of a reactive dehydrochlorination of the ester was viewed as the most likely product, along with generous amounts of heat.

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Methyl trichloroacetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl trichloroacetate Suppliers

Shanghai Kaisai Chemical Co., Ltd
Tel
021-33516722 13701817765
Fax
021-33516776
Email
kaisaichem@163.com
Country
China
ProdList
4741
Advantage
58
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
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View Lastest Price from Methyl trichloroacetate manufacturers

Career Henan Chemical Co
Product
Methyl trichloroacetate 598-99-2
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200kgs
Release date
2020-01-10

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