ChemicalBook > CAS DataBase List > 4-Hydroxymethyl Loratadine

4-Hydroxymethyl Loratadine

Product Name
4-Hydroxymethyl Loratadine
CAS No.
609806-40-8
Chemical Name
4-Hydroxymethyl Loratadine
Synonyms
5]cyclohepta[1;6-dihydrobenzo[4;Loratadine Impurity 23;Loratadine Impurity 4;Loratadine?4-Hydroxymethyl?Impurity;2-hydroxy-54-(methylthio)butanamide;Loratidine -4-hydrpxymethyl Impurity;ethyl 4-[8-chloro-4-(hydroxymethyl)-5;Loratadine 4-Hydroxymethyl Impurity (USP);2-b]pyridin-11-ylidene]piperidine-1-carboxylate
CBNumber
CB51175878
Molecular Formula
C23H25ClN2O3
Formula Weight
412.91
MOL File
609806-40-8.mol
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4-Hydroxymethyl Loratadine Property

Melting point:
73-75°C
Boiling point:
594.2±50.0 °C(Predicted)
Density 
1.301±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
form 
Solid
pka
13.56±0.10(Predicted)
color 
Pale Yellow
Stability:
Hygroscopic
InChI
InChI=1S/C23H25ClN2O3/c1-2-29-23(28)26-11-8-15(9-12-26)21-19-6-4-18(24)13-16(19)3-5-20-17(14-27)7-10-25-22(20)21/h4,6-7,10,13,27H,2-3,5,8-9,11-12,14H2,1H3
InChIKey
BCKYTUFUNAGTDV-UHFFFAOYSA-N
SMILES
N1(C(OCC)=O)CC/C(=C2\C3=NC=CC(CO)=C3CCC3=CC(Cl)=CC=C3\2)/CC1
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0000267
Product name
4-HYDROXY METHYL LORATADINE
Purity
95.00%
Packaging
1MG
Price
$704.55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0000267
Product name
4-HYDROXY METHYL LORATADINE
Purity
95.00%
Packaging
10MG
Price
$3342.15
Updated
2021/12/16
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4-Hydroxymethyl Loratadine Chemical Properties,Usage,Production

Chemical Properties

Light-Yellow Solid

Uses

A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor.

Definition

ChEBI: 4-Hydroxymethyl Loratadine is a benzocycloheptapyridine.

4-Hydroxymethyl Loratadine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Hydroxymethyl Loratadine manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD
Product
4-Hydroxymethyl Loratadine 609806-40-8
Price
US $0.00/mg
Min. Order
10mg
Purity
0.98
Supply Ability
10g
Release date
2024-04-01

609806-40-8, 4-Hydroxymethyl LoratadineRelated Search:


  • ethyl 4-[8-chloro-4-(hydroxymethyl)-5,6-dihydrobenzo[4,5]cyclohepta[1,2-b]pyridin-11-ylidene]piperidine-1-carboxylate
  • Loratadine 4-Hydroxymethyl Impurity (USP)
  • 4-[8-Chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Este
  • 4-[8-Chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Ester
  • Ethyl 4-[8-chloro-5,6-dihydro-4-(hydroxy methyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidine carboxylate
  • Loratadine Impurity 4
  • Loratadine Impurity 23
  • 1-Piperidinecarboxylic acid, 4-[8-chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-, ethyl ester
  • 4-Hydroxymethyl Loratadine DISCONTINUED. Please see H949915
  • Loratadine?4-Hydroxymethyl?Impurity
  • Loratidine -4-hydrpxymethyl Impurity
  • 2-hydroxy-54-(methylthio)butanamide
  • 2-b]pyridin-11-ylidene]piperidine-1-carboxylate
  • 5]cyclohepta[1
  • 6-dihydrobenzo[4
  • ethyl 4-[8-chloro-4-(hydroxymethyl)-5
  • 609806-40-8
  • C23H25ClN2O3
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals