2,3,5-Tri-O-benzyl-D-ribonolactone

Physical Form

Product Name: 2,3,5-Tri-O-benzyl-D-ribonolactone
CAS No.: 55094-52-5
Chemical Name: 2,3,5-Tri-O-benzyl-D-ribonolactone
Synonyms: 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone;(3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxyMethyl)-dihydrofuran-2(3H)-one;2,3,5-Tri-O-benzyl-D-ribonic Acid 1,4-lactone;1-Chloro-3,5-di-(p-chlorobenzoyl)-2-deoxy-D-ribofuranose;-D-RIBONO-1,4-L;JACS-55094-52-5;Redesivir Impurity 6;2,3, 5-tribenzoxy-d-ribonolactone;2,3,5-TRI-O-BENZYL-D-RIBONOLACTONE;Pentanedioicacid,7-oxo-,diethylester
CBNumber: CB51180311
Molecular Formula: C26H26O5
Formula Weight: 418.49
MOL File: 55094-52-5.mol

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2,3,5-Tri-O-benzyl-D-ribonolactone Property

Melting point:: 54-55 °C
Boiling point:: 576.8±50.0 °C(Predicted)
Density: 1.21±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), DMSO (Slightly, Sonicated), Methanol (Slightly)
form: Solid
color: White to Pale Yellow
optical activity: Consistent with structure
InChI: InChI=1/C26H26O5/c27-26-25(30-18-22-14-8-3-9-15-22)24(29-17-21-12-6-2-7-13-21)23(31-26)19-28-16-20-10-4-1-5-11-20/h1-15,23-25H,16-19H2/t23-,24-,25-/s3
InChIKey: LDHBSABBBAUMCZ-HIIPYKDHNA-N
SMILES: O([C@@H]1[C@H](OC(=O)[C@@H]1OCC1C=CC=CC=1)COCC1C=CC=CC=1)CC1C=CC=CC=1 |&1:1,2,6,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: T3955
Product name: 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
Packaging: 5G
Price: $87
Updated: 2025/07/31

TCI Chemical

Product number: T3955
Product name: 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
Packaging: 25G
Price: $260
Updated: 2025/07/31

TRC

Product number: T771378
Product name: 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
Packaging: 25g
Price: $175
Updated: 2021/12/16

Usbiological

Product number: 294781
Product name: 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
Packaging: 1g
Price: $355
Updated: 2021/12/16

Biosynth Carbosynth

Product number: MT05275
Product name: 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
Packaging: 100g
Price: $500
Updated: 2021/12/16

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2,3,5-Tri-O-benzyl-D-ribonolactone Chemical Properties,Usage,Production

Physical Form

Solid

Application

2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a useful research chemical.

Synthesis

16838-89-4

14233-64-8

General procedure for the synthesis of 2,3,5-tribenzyloxy-D-arabinofuranous acid-1,4-lactone from 2,3,5-tri-O-(phenylmethyl)-D-ribofuranose: Compound 30a (prepared according to J. Org. Chem., 1961, 26, 4605; 10.0 g, 23.8 mmol) was dissolved in anhydrous DMSO (30 mL) and stirred under nitrogen protection. Acetic anhydride (20 mL) was then added and the reaction mixture was stirred continuously for 48 h at room temperature. After the completion of the reaction was monitored by LC/MS, the reaction mixture was slowly poured into ice water (500 mL) and stirring was continued for 20 min. The aqueous phase was extracted with ethyl acetate (3 × 200 mL), and the organic phase was combined and washed with deionized water (3 × 200 mL). The aqueous phase was discarded and the organic phase was dried over anhydrous MgSO4 and concentrated to dryness under reduced pressure. The residue was dissolved in dichloromethane (DCM) and purified by silica gel column chromatography using 25% ethyl acetate/hexane as eluent to give the target product 30b in 96% yield.1H-NMR (CD3CN) data: δ 3.63-3.75 (m, 2H), 4.27 (d, 1H), 4.50-4.57 (m, 3H), and 4.65 (s, 3H), 4.69-4.80 (m, 2H), 7.25 (d, 2H), 7.39 (m, 13H).

References

[1] Patent: WO2010/93608, 2010, A1. Location in patent: Page/Page column 158
[2] Patent: WO2011/35250, 2011, A1. Location in patent: Page/Page column 70-71
[3] Patent: WO2012/12776, 2012, A1. Location in patent: Page/Page column 109
[4] Patent: US2017/71964, 2017, A1. Location in patent: Paragraph 0517-0518
[5] Journal of Carbohydrate Chemistry, 2008, vol. 27, # 5, p. 332 - 344

2,3,5-Tri-O-benzyl-D-ribonolactone Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3,5-Tri-O-benzyl-D-ribonolactone Suppliers

China 287 Europe 1 India 11 Japan 1 United Kingdom 2 United States 8 Global 310

Syngenesis Chemscience Private Limited

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CHEMSWORTH

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View Lastest Price from 2,3,5-Tri-O-benzyl-D-ribonolactone manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2,3,5-Tri-O-benzyl-D-ribonolactone 55094-52-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kgs
Release date: 2025-09-25

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2,3,5-Tri-O-benzyl-D-ribonolactone 55094-52-5
Price: US $0.00-0.00/KG
Min. Order: 100g
Purity: 98%min HPLC
Supply Ability: 100kg
Release date: 2021-06-02

Speranza Chemical Co., Ltd.

Product: 2,3,5-Tri-O-benzyl-D-ribonolactone 55094-52-5
Price: US $20000.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg/month
Release date: 2020-07-16

55094-52-5, 2,3,5-Tri-O-benzyl-D-ribonolactoneRelated Search:

Benzyl alcohol 4-Methoxybenzylchloride TRIOXSALEN D-(+)-Glucono-1,5-lactone Spironolactone D-Glucurone Benzyl RIBONIC ACID 2,3,5-Tri-O-benzoyl-2-C-methyl-D-ribonic acid-1,4-lactone D-ERYTHRONOLACTONE 2,3,5-Tri-O-benzyl-D-ribose D(+)-Ribonic acid gamma-lactone D-LYXONO-1,4-LACTONE 5-O-Benzyl-D-ribose 2,3,5-Tri-O-benzyl-D-ribonolactone (R)-3-BENZYLOXY-PENTANOIC ACID

1-Chloro-3,5-di-(p-chlorobenzoyl)-2-deoxy-D-ribofuranose

2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone

2,3,5-TRI-O-BENZYL-D-RIBONOLACTONE

(3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxyMethyl)-dihydrofuran-2(3H)-one

2,3,5-Tris-O-(phenylmethyl)-D-ribonic acid γ-lactone

(3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]oxolan-2-one

2,2,5-tri-O-benzyl-D-ribono-1,4-lancton

2,3,5-Tri-O-benzyl-D-ribonic Acid 1,4-lactone

JACS-55094-52-5

-D-RIBONO-1,4-L

D-Ribonic acid, 2,3,5-tris-O-(phenylmethyl)-, γ-lactone

2,3,5-Tris-O-(phenylmethyl)-D-ribonic acid γ-lactone, 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone

1, 4-lactone, 2,3, 5-tribenzoxy-D-ribosate-1, 4-lactone

(3R,5R)-3,4--bis(phenylmethoxy)-5-(phenylmethoxyethyl)oxolan-2-one

(3R,4R,5R)-3,4-bis(phenylmethoxy)-5-(phenylmethoxymethyl)oxolan-2-one

(3R,4R,5R)-3,4-dibenzyloxy-5-(benzyloxymethyl)tetrahydrofuran-2-one

Pentanedioicacid,7-oxo-,diethylester

2,3, 5-tribenzoxy-d-ribonolactone

Redesivir Impurity 6

2,3,5-Tribenzyloxy-D-ribono-1,4-lactone

2,3,5-Tribenzyloxy-D-ribonicacid1,4-lactone

55094-52-5

C26H26O5

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