GERANYLGERANIOL
- Product Name
- GERANYLGERANIOL
- CAS No.
- 24034-73-9
- Chemical Name
- GERANYLGERANIOL
- Synonyms
- (2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol;(E,E,E)-Geranylgeranyl alcohol;CJ24095;CJ 24095;CJ-24095;FT0626663;FT-0626663;Tetraprenol;Geranylgeranio;GERANYLGERANIOL
- CBNumber
- CB5120277
- Molecular Formula
- C20H34O
- Formula Weight
- 290.48
- MOL File
- 24034-73-9.mol
GERANYLGERANIOL Property
- Boiling point:
- 152-153 °C(Press: 0.07 Torr)
- Density
- 0.8930 g/cm3(Temp: 18 °C)
- storage temp.
- -20°C
- solubility
- Chloroform (Sparingly), Dichloromethane (Slightly), Ethyl Acetate (Slightly)
- form
- liquid
- pka
- 14.42±0.10(Predicted)
- color
- Colourless to Light Yellow
- BRN
- 1913779
- Stability:
- Light Sensistive, Temperature Sensitive
- Cosmetics Ingredients Functions
- HUMECTANT
ANTIMICROBIAL
ANTIOXIDANT - InChI
- InChI=1S/C20H34O/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-21/h9,11,13,15,21H,6-8,10,12,14,16H2,1-5H3/b18-11+,19-13+,20-15+
- InChIKey
- OJISWRZIEWCUBN-QIRCYJPOSA-N
- SMILES
- C(O)/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- G3278
- Product name
- Geranylgeraniol
- Purity
- ≥85% (GC)
- Packaging
- 100mg
- Price
- $91.9
- Updated
- 2026/03/19
- Product number
- 13272
- Product name
- Geranylgeranyl Alcohol
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $28
- Updated
- 2024/03/01
- Product number
- 13272
- Product name
- Geranylgeranyl Alcohol
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $43
- Updated
- 2024/03/01
- Product number
- 13272
- Product name
- Geranylgeranyl Alcohol
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- G367500
- Product name
- Geranylgeraniol(Natural)
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
GERANYLGERANIOL Chemical Properties,Usage,Production
Chemical Properties
Light Yellow Oil
Uses
A intermediate in the lipidation of proteins, which plays a great importance for a variety of biological processes such as cell signalling
Uses
Geranylgeraniol, a precursor to Geranylgeranylpyrophosphate (G367600), is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-adsorption, inhibition of osteoclast formation, and kinase activation in vitro.
Definition
ChEBI: Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.
Biochem/physiol Actions
As the pyrophosphate, the metabolic precursor of all diterpenes. Screening in vitro shows this to be a potent and selective agent against Mycobacterium tuberculosis.
in vivo
Geranylgeraniol (725 mg/kg/d; p.o.; 90 d) is not toxicologically significant with a dose below 725 mg/kg/d in rats[3].
Geranylgeraniol (483 mg/kg/d; p.o.; 10 d) suppresses lipopolysaccharide-induced inflammation via inhibition of nuclear factor-κB activation in rats[4].
| Animal Model: | Han Wistar rats (169-192 g for male; 116-152 g for female)[3] |
| Dosage: | 0, 725, 1450, and 2900 mg/kg |
| Administration: | Oral gavage; once daily; 90 days |
| Result: | Showed the lowest observed adverse effect level (LOAEL) for local effects and the no observed adverse effect level (NOAEL) for systemic effects as 725 mg/kg/d. Reduced body weights by 12.9 and 21.6% in the intermediate- and high-dose group males, respectively, compared to controls. |
| Animal Model: | Wistar rats (male, 8-week-old, 130-150 g)[4] |
| Dosage: | 0, 48.3, 483, 4830 mg/kg |
| Administration: | Oral gavage; once daily; 10 days; with or not LPS challenge (i.p.; 0.5 mg/kg) |
| Result: | Suppressed LPS-induced inflammatory cytokines and mRNA expression of LPS-induced inflammatory genes in liver with doses of 483 mg/kg and 4830 mg/kg. Suppressed protein levels of IRAK1, TRAF6, and TAK1, originating from transcriptional down-regulation with doses of 483 mg/kg and 4830 mg/kg. |
GERANYLGERANIOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from GERANYLGERANIOL manufacturers
- Product
- Geranylgeraniol 24034-73-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 95.0%
- Supply Ability
- 10000KGS
- Release date
- 2024-11-11
- Product
- GERANYLGERANIOL 24034-73-9
- Price
- US $8.00-0.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-28
- Product
- GERANYLGERANIOL 24034-73-9
- Price
- US $1.00/KG
- Min. Order
- 1G
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-08-15