GERANYLGERANIOL

Product Name: GERANYLGERANIOL
CAS No.: 24034-73-9
Chemical Name: GERANYLGERANIOL
Synonyms: (2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol;(E,E,E)-Geranylgeranyl alcohol;CJ24095;CJ 24095;CJ-24095;FT0626663;FT-0626663;Tetraprenol;Geranylgeranio;GERANYLGERANIOL
CBNumber: CB5120277
Molecular Formula: C20H34O
Formula Weight: 290.48
MOL File: 24034-73-9.mol

More

Less

GERANYLGERANIOL Property

Boiling point:: 152-153 °C(Press: 0.07 Torr)
Density: 0.8930 g/cm3(Temp: 18 °C)
storage temp.: -20°C
solubility: Chloroform (Sparingly), Dichloromethane (Slightly), Ethyl Acetate (Slightly)
form: liquid
pka: 14.42±0.10(Predicted)
color: Colourless to Light Yellow
BRN: 1913779
Stability:: Light Sensistive, Temperature Sensitive
InChI: InChI=1S/C20H34O/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-21/h9,11,13,15,21H,6-8,10,12,14,16H2,1-5H3/b18-11+,19-13+,20-15+
InChIKey: OJISWRZIEWCUBN-QIRCYJPOSA-N
SMILES: C(O)/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29052290

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G3278
Product name: Geranylgeraniol
Purity: ≥85% (GC)
Packaging: 100mg
Price: $85.8
Updated: 2025/07/31

Cayman Chemical

Product number: 13272
Product name: Geranylgeranyl Alcohol
Purity: ≥98%
Packaging: 25mg
Price: $28
Updated: 2024/03/01

Cayman Chemical

Product number: 13272
Product name: Geranylgeranyl Alcohol
Purity: ≥98%
Packaging: 50mg
Price: $43
Updated: 2024/03/01

Cayman Chemical

Product number: 13272
Product name: Geranylgeranyl Alcohol
Purity: ≥98%
Packaging: 100mg
Price: $68
Updated: 2024/03/01

TRC

Product number: G367500
Product name: Geranylgeraniol(Natural)
Packaging: 50mg
Price: $45
Updated: 2021/12/16

More

Less

GERANYLGERANIOL Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Oil

Uses

A intermediate in the lipidation of proteins, which plays a great importance for a variety of biological processes such as cell signalling

Uses

Geranylgeraniol, a precursor to Geranylgeranylpyrophosphate (G367600), is an intermediate in the mevalonate pathway. Geranylgeraniol has been shown to prevent bone re-adsorption, inhibition of osteoclast formation, and kinase activation in vitro.

Definition

ChEBI: Geranylgeraniol is a diterpenoid that is hexadeca-2,6,10,14-tetraene substituted by methyl groups at positions 3, 7, 11 and 15 and a hydroxy group at position 1. It has a role as a plant metabolite, a volatile oil component and an antileishmanial agent. It is a diterpenoid and a polyprenol.

Biochem/physiol Actions

As the pyrophosphate, the metabolic precursor of all diterpenes. Screening in vitro shows this to be a potent and selective agent against Mycobacterium tuberculosis.

in vivo

Geranylgeraniol (725 mg/kg/d; p.o.; 90 d) is not toxicologically significant with a dose below 725 mg/kg/d in rats^[3].
Geranylgeraniol (483 mg/kg/d; p.o.; 10 d) suppresses lipopolysaccharide-induced inflammation via inhibition of nuclear factor-κB activation in rats^[4].

Animal Model:	Han Wistar rats (169-192 g for male; 116-152 g for female)^[3]
Dosage:	0, 725, 1450, and 2900 mg/kg
Administration:	Oral gavage; once daily; 90 days
Result:	Showed the lowest observed adverse effect level (LOAEL) for local effects and the no observed adverse effect level (NOAEL) for systemic effects as 725 mg/kg/d. Reduced body weights by 12.9 and 21.6% in the intermediate- and high-dose group males, respectively, compared to controls.

Animal Model:	Wistar rats (male, 8-week-old, 130-150 g)^[4]
Dosage:	0, 48.3, 483, 4830 mg/kg
Administration:	Oral gavage; once daily; 10 days; with or not LPS challenge (i.p.; 0.5 mg/kg)
Result:	Suppressed LPS-induced inflammatory cytokines and mRNA expression of LPS-induced inflammatory genes in liver with doses of 483 mg/kg and 4830 mg/kg. Suppressed protein levels of IRAK1, TRAF6, and TAK1, originating from transcriptional down-regulation with doses of 483 mg/kg and 4830 mg/kg.

GERANYLGERANIOL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

GERANYLGERANIOL Suppliers

Canada 1 China 163 Germany 2 India 1 Italy 1 Switzerland 2 United Kingdom 5 United States 14 Global 189

Shanghai Linka Biotechnology Co., Ltd.

Tel: 18301977208
Fax: qq2126935757
Email: 2126935757@qq.com
Country: China
ProdList: 214
Advantage: 55

Zhengzhou anmousse chemical products co. LTD

Tel: 0371-55289822 18737195735
Fax: QQ:483339295
Email: 483339295@qq.com
Country: China
ProdList: 7587
Advantage: 58

Originchem Co., Ltd

Tel: 0523-0523-86200346 15996028822
Fax: 0523-86200341
Email: 1583458435@qq.com
Country: China
ProdList: 71
Advantage: 58

Chongqing Botao Biotechnology Co., LTD

Tel: 15223382610
Email: danny@chemdad.com
Country: China
ProdList: 2032
Advantage: 58

Shanghai Jindi Pharmaceutical Technology Co., Ltd

Tel: 13564401937
Email: wangtao@jindipharma.com.cn
Country: China
ProdList: 22
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

More

Less

View Lastest Price from GERANYLGERANIOL manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Geranylgeraniol 24034-73-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 95.0%
Supply Ability: 10000KGS
Release date: 2024-11-11

Henan Fengda Chemical Co., Ltd

Product: GERANYLGERANIOL 24034-73-9
Price: US $8.00-0.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

Career Henan Chemical Co

Product: GERANYLGERANIOL 24034-73-9
Price: US $1.00/KG
Min. Order: 1G
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-15

24034-73-9, GERANYLGERANIOLRelated Search:

Geraniol Geranyl linalool GERANYL CHLORIDE Citronellol CARVONE Sclareol Carvacrol Sclareolide CARVEOL EICOSAPRENOL DECAPRENYL-MPDA TRIDECAPRENOL DODECAPRENYL-MPDA DECAPRENOL Solanesol HEPTAPRENYL-MPDA OCTADECAPRENYL-MPDA OCTADECAPRENOL

Geranylgeraniol (Natural)

GERANYLGERANIOL

Geranylgeraniol (mixture of isomers)

2,6,10,14-Hexadecatetraen-1-ol, 3,7,11,15-tetramethyl-, (2E,6E,10E)-

(2E,6E,10E)-3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetren-1-ol

(2E,6E,10E)-3,7,11,15-Tetramethylhexadecane-2,6,10,14-tetrene-1-ol

all-E-Geranylgeraniol

ALL TRANS-3,7,11,15-TETRAMETHYL-2,6,10,14-HEXADECATETRAEN-1-OL

ALL TRANS GERANYL GERANIOL

3,7,11,15-TETRAMETHYL-2,6,10,14-HEXADECATETRAEN-1-OL

3,7,11,15-TETRAMETHYL-2,6,10,14-HEXADECATRAEN-1-OL

(2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol

Geranylgeranyl Alcohol

(E,E,E)-Geranylgeranyl alcohol

Geranylgeraniol (Synthetic)

Geranylgeraniol(GGOH)

Teprenone Impurity 26 (Geranylgeraniol)

GERANYLGERANIOL USP/EP/BP

Geranylgeraniol (Natural) ~85%

TeprenoneImpurity26

CJ 24095

CJ24095

CJ-24095

FT0626663

FT-0626663

Tetraprenol

mitochondria,neuronal death,neuroinflammation,apoptosis,cholesterol pathway,NF-κB,inhibit,LPS-induced,Geranylgeraniol,microglial inflammation,Nuclear factor-kappaB,Nuclear factor-κB,mevalonate,Inhibitor

Menatetrenone ImpuritiesE

Geranylgeraniol, 10 mM in DMSO

Geranylgeranio

24034-73-9

24064-73-9

Biochemicals and Reagents

BioChemical

Substrate Analogs

Enzyme Inhibitors

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Type

Miscellaneous Natural Products

Mixed Fatty Acids

Fatty Acid Derivatives & Lipids

Glycerols