2,6-DIIODOPYRAZINE
- Product Name
- 2,6-DIIODOPYRAZINE
- CAS No.
- 58138-79-7
- Chemical Name
- 2,6-DIIODOPYRAZINE
- Synonyms
- 2,6-Diiodopyrizine;2,6-DIIODOPYRAZINE;Pyrazine, 2,6-diiodo-
- CBNumber
- CB51215884
- Molecular Formula
- C4H2I2N2
- Formula Weight
- 331.88
- MOL File
- 58138-79-7.mol
2,6-DIIODOPYRAZINE Property
- Boiling point:
- 329.7±37.0 °C(Predicted)
- Density
- 2.765±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- -2.62±0.10(Predicted)
- form
- solid
- color
- White
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SYX00011
- Product name
- 2,6-Diiodopyrazine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $167
- Updated
- 2023/01/07
- Product number
- D492708
- Product name
- 2,6-Diiodopyrazine
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FD147794
- Product name
- 2,6-Diiodopyrazine
- Packaging
- 250mg
- Price
- $112.5
- Updated
- 2021/12/16
- Product number
- 3H32-H-86
- Product name
- 2,6-Diiodopyrazine
- Purity
- 95%
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- W7134
- Product name
- 2,6-Diiodopyrazine
- Packaging
- 1g
- Price
- $123
- Updated
- 2021/12/16
2,6-DIIODOPYRAZINE Chemical Properties,Usage,Production
Synthesis
4774-14-5
58138-79-7
General procedure for the synthesis of 2,6-diiodopyrazine from 2,6-dichloropyrazine: 2,6-dichloropyrazine (2.5 g, 16.8 mmol, 1.0 eq.), p-toluenesulfonic acid (6.4 g, 33.6 mmol, 2.0 eq.), sodium iodide (20.0 g, 133.3 mmol, 8.0 eq.), 15-crown-5 (2.0 mL), and cyclobutanesulfone (40 mL) were mixed in a sealed tube and the reaction was heated at 150 °C for 2 hours. After completion of the reaction, the mixture was cooled to room temperature and water (100 mL) was added to the reaction mixture. The reaction mixture was neutralized with saturated sodium bicarbonate solution and subsequently washed with saturated sodium thiosulfate solution. The mixture was extracted with ether (5 x 100 mL), the ether extracts were combined, dried with anhydrous sodium sulfate and concentrated under reduced pressure. Water (10 mL) was added to the concentrate to precipitate 2,6-diiodopyrazine, the solid was collected by filtration, washed sequentially with water and pentane, and freeze-dried to give a light yellow powdery product (2.1 g, 38% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 8.74 (s, 2H); mass spectrum (M+H)+ = 332, retention time (Rt) = 1.29 min.
References
[1] Angewandte Chemie - International Edition, 2015, vol. 54, # 34, p. 9971 - 9975
[2] Angew. Chem., 2015, vol. 127, p. 10109 - 10113,5
[3] Journal of Heterocyclic Chemistry, 1994, vol. 31, # 6, p. 1449 - 1454
[4] Patent: WO2008/24390, 2008, A2. Location in patent: Page/Page column 52
[5] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 13, p. 4358 - 4361
2,6-DIIODOPYRAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
2,6-DIIODOPYRAZINE Suppliers
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 001-857-928-2050 or 1-888-588-9418
- Fax
- 001-617-206-9595
- sales@chemreagents.com
- Country
- United States
- ProdList
- 10186
- Advantage
- 62
- Tel
- 021-50795510 4000665055
- Fax
- 021-50795055
- sales@accelachem.com
- Country
- China
- ProdList
- 11035
- Advantage
- 64
- Tel
- +86 (21) 6435-5022
- Country
- China
- ProdList
- 4267
- Advantage
- 65
- Tel
- 0931-4190454 13893344397
- Fax
- +86-931-8506154
- sales@kyxpharma.com
- Country
- China
- ProdList
- 310
- Advantage
- 55
- Tel
- 021-31261262/ 49 (0)17662837245
- Fax
- (0)21-33250524
- sales@novochemy.com
- Country
- Germany
- ProdList
- 6328
- Advantage
- 58
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 18209
- Advantage
- 56
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
View Lastest Price from 2,6-DIIODOPYRAZINE manufacturers
- Product
- 2,6-DIIODOPYRAZINE 58138-79-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- 2,6-DIIODOPYRAZINE 58138-79-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09