Iodopyrazine

Product Name: Iodopyrazine
CAS No.: 32111-21-0
Chemical Name: Iodopyrazine
Synonyms: 2-IODOPYRAZINE;IODOPYRAZINE;Iodopyrazine>Iodopyrazine,97%;Iodopyrazine 97%;Pyrazine, 2-iodo-;2-Iodopyrazine,95%;2-Iodo-1,4-diazine;2-IODOPYRAZINE 97%;2-Iodopyrazine,Iodopyrazine
CBNumber: CB5386987
Molecular Formula: C4H3IN2
Formula Weight: 205.98
MOL File: 32111-21-0.mol

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Iodopyrazine Property

Melting point:: 90 °C (decomp)
Boiling point:: 109-110 °C34 mm Hg(lit.)
Density: 2.086 g/mL at 25 °C(lit.)
refractive index: n20/D 1.655(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: -0.85±0.10(Predicted)
form: Crystalline Powder
color: White to pale yellow
Sensitive: Light Sensitive
InChI: InChI=1S/C4H3IN2/c5-4-3-6-1-2-7-4/h1-3H
InChIKey: OYWPFIUVDKHHGQ-UHFFFAOYSA-N
SMILES: C1(I)=NC=CN=C1
CAS DataBase Reference: 32111-21-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 513164
Product name: Iodopyrazine
Purity: 97%
Packaging: 5g
Price: $37.24
Updated: 2025/07/31

Sigma-Aldrich

Product number: 513164
Product name: Iodopyrazine
Purity: 97%
Packaging: 1g
Price: $47.9
Updated: 2023/06/20

TCI Chemical

Product number: I0837
Product name: 2-Iodopyrazine
Purity: >97.0%(GC)
Packaging: 1g
Price: $44
Updated: 2025/07/31

TCI Chemical

Product number: I0837
Product name: 2-Iodopyrazine
Purity: >97.0%(GC)
Packaging: 5g
Price: $148
Updated: 2025/07/31

TRC

Product number: I737033
Product name: 2-Iodopyrazine
Packaging: 50mg
Price: $60
Updated: 2021/12/16

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Iodopyrazine Chemical Properties,Usage,Production

Chemical Properties

Colorless to brown liquid

Synthesis

14508-49-7

32111-21-0

General procedure for the synthesis of 2-iodopyrazine from 2-chloropyrazine: a reaction mixture of 2-chloropyrazine (7.5 mL, 83 mmol), NaI (30.3 g, 202 mmol), HOAc (9.6 mL, 168 mmol) and H2SO4 (0.5 mL) in MeCN (105 mL) was heated and refluxed for 4.5 hours. Upon completion of the reaction, the solvent was removed under reduced pressure and water (120 mL) was added. The solution was alkalized with saturated NaHCO3 solution and extracted with dichloromethane (DCM) (2 x 125 mL). The DCM layers were combined, washed sequentially with saturated Na2S2O3 solution and brine, and dried over anhydrous Na2SO4. The solvent was removed under reduced pressure to give the crude 2-iodopyrazine as an oil (12.33 g, 20% yield, 71% purity).1H NMR analysis showed that the crude contained less than about 10 mol% of 2-chloropyrazine. Following the same procedure, another batch of 2-chloropyrazine (50 g, 437 mmol) was converted to the crude 2-iodopyrazine (~65 g). The two crude batches were combined and distilled under reduced pressure (ca. 0.75 Torr, boiling point 47 °C) to give 64 g of pure 2-iodopyrazine (60% yield).1H-NMR (CDCl3, 300 MHz) δ 8.40 (dd, J = 1.8, 2.4 Hz, 1H), 8.51 (d, J = 2.4 Hz, 1H), 8.87 (d, J = 1.5 Hz, 1H).

References

[1] Tetrahedron, 1998, vol. 54, # 33, p. 9701 - 9710
[2] Patent: WO2009/114313, 2009, A2. Location in patent: Page/Page column 15

Iodopyrazine Preparation Products And Raw materials

Raw materials

Preparation Products

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Iodopyrazine Suppliers

Americas 1 China 149 Czech Republic 1 Europe 1 France 1 Germany 3 India 4 Japan 1 Slovakia 1 Switzerland 1 United Kingdom 4 United States 18 Global 185

Shanghai Wuping Biological Technology Co., Ltd.

Tel: 18501609135
Fax: -
Email: 182517690@qq.com
Country: China
ProdList: 219
Advantage: 55

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 993
Advantage: 62

Fengcheng Meditech (Tianjin)Co., Ltd

Tel: 022-59002498-8008; 15122574756
Email: info@fcmeditech.com
Country: China
ProdList: 68
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

ZHIWE CHEMTECH CO LTD

Tel: 021-20221225 13917446399
Fax: QQ:115820162
Email: zwchem@163.com
Country: China
ProdList: 617
Advantage: 61

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing HwrkChemical Technology Co., Ltd

Tel: 18515581800 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9400
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

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View Lastest Price from Iodopyrazine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Iodopyrazine 32111-21-0
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%+
Supply Ability: 800 tons
Release date: 2020-04-29

Career Henan Chemical Co

Product: Iodopyrazine 32111-21-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2018-08-09

32111-21-0, IodopyrazineRelated Search:

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IODOPYRAZINE

2-IODOPYRAZINE 97%

Iodopyrazine,97%

2-Iodo-1,4-diazine

2-Iodopyrazine,95%

2-IODOPYRAZINE

Iodopyrazine 97%

Iodopyrazine&gt

Pyrazine, 2-iodo-

Iodopyrazine ISO 9001：2015 REACH

2-Iodopyrazine,Iodopyrazine

32111-21-0

209-37-9

290-37-6 290-37-9

C4H3IN2

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Heterocyclic Building Blocks

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alkyl Iodine

Building Blocks

Chemical Synthesis

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Pyrazine

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