2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
- Product Name
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
- CAS No.
- 168640-82-2
- Chemical Name
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
- Synonyms
- N?-PEG4-Ots;N3-PEG4-OTs;N3-PEG4-Tos;Azido-PEG4-Tos;Azido-PEG4-OTs;Azide-PEG4-Tos Azide-PEG4-Tos;11-Azido-3,6,9-trioxaundecanyl p-toluenesulfonate;2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate;2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol;N3-PEG4-Tos/Ethanol, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate)
- CBNumber
- CB51231413
- Molecular Formula
- C13H19N3O5S
- Formula Weight
- 0
- MOL File
- 168640-82-2.mol
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- A926503
- Product name
- Azide-PEG4-Tos
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FA07579
- Product name
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
- Packaging
- 25mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA07579
- Product name
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
- Packaging
- 50mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FA07579
- Product name
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
- Packaging
- 100mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FA07579
- Product name
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Chemical Properties,Usage,Production
Description
Azide-PEG4-Tos is a heterofunctional crosslinker containing an azide (N3) group and a tosyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions. PEG spacer increases solubility in aqueous media.
Uses
Azide-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG4-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Preparation Products And Raw materials
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View Lastest Price from 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol manufacturers
- Product
- 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol 168640-82-2
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-12
- Product
- Azido-PEG4-Tos 168640-82-2
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >99.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23