ChemicalBook > CAS DataBase List > 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol

2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol

Product Name
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
CAS No.
168640-82-2
Chemical Name
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Synonyms
N?-PEG4-Ots;N3-PEG4-OTs;N3-PEG4-Tos;Azido-PEG4-Tos;Azido-PEG4-OTs;Azide-PEG4-Tos Azide-PEG4-Tos;11-Azido-3,6,9-trioxaundecanyl p-toluenesulfonate;2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate;2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol;N3-PEG4-Tos/Ethanol, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate)
CBNumber
CB51231413
Molecular Formula
C13H19N3O5S
Formula Weight
0
MOL File
168640-82-2.mol
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2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Property

storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in DMSO, DCM, DMF
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A926503
Product name
Azide-PEG4-Tos
Packaging
5mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA07579
Product name
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Packaging
25mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA07579
Product name
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Packaging
50mg
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA07579
Product name
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Packaging
100mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA07579
Product name
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
Packaging
250mg
Price
$250
Updated
2021/12/16
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2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Chemical Properties,Usage,Production

Description

Azide-PEG4-Tos is a heterofunctional crosslinker containing an azide (N3) group and a tosyl group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The tosyl group is a good leaving group for nucleophilic substitution reactions. PEG spacer increases solubility in aqueous media.

Uses

Azide-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azide-PEG4-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol 168640-82-2
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2025-09-12
Xian confluore Biological Technology Co., Ltd.
Product
Azido-PEG4-Tos 168640-82-2
Price
US $0.00/g
Min. Order
1g
Purity
>99.00%
Supply Ability
1g
Release date
2024-03-23

168640-82-2, 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanolRelated Search:


  • 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]-1-(p-toluenesulfonyl)-ethanol
  • Azido-PEG4-Tos
  • 2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate
  • 11-Azido-3,6,9-trioxaundecanyl p-toluenesulfonate
  • N3-PEG4-Tos
  • Azido-PEG4-OTs
  • N3-PEG4-OTs
  • N3-PEG4-Tos/Ethanol, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1-(4-methylbenzenesulfonate)
  • Azide-PEG4-Tos Azide-PEG4-Tos
  • N?-PEG4-Ots
  • 168640-82-2
  • peg