BOVINE PINEAL ANTIREPRODUCTIVE TRIPEPTIDE ACETATE SALT
- Product Name
- BOVINE PINEAL ANTIREPRODUCTIVE TRIPEPTIDE ACETATE SALT
- CAS No.
- 71730-64-8
- Chemical Name
- BOVINE PINEAL ANTIREPRODUCTIVE TRIPEPTIDE ACETATE SALT
- Synonyms
- THR-SER-LYS;H-Thr-Ser-Lys-OH;thr-ser-lys acetate;threonyl-seryl-lysine;Thr-Ser-Lys acetate salt;H-THR-SER-LYS-OH ACETATE SALT;threonine-serine-lysine acetate;THR-SER-LYS (THR-SER-LYS ACETATE);L-Lysine, N2-(N-L-threonyl-L-seryl)-;BOVINE PINEAL ANTIREPRODUCTIVE PEPTIDE
- CBNumber
- CB5123834
- Molecular Formula
- C13H26N4O6
- Formula Weight
- 334.37
- MOL File
- 71730-64-8.mol
BOVINE PINEAL ANTIREPRODUCTIVE TRIPEPTIDE ACETATE SALT Property
- storage temp.
- -15°C
N-Bromosuccinimide Price
- Product number
- FB109446
- Product name
- Bovine Pineal Antireproductive Tripeptide acetate salt H-Thr-Ser-Lys-OH acetate salt
- Packaging
- 25mg
- Price
- $121
- Updated
- 2021/12/16
- Product number
- FB109446
- Product name
- Bovine Pineal Antireproductive Tripeptide acetate salt H-Thr-Ser-Lys-OH acetate salt
- Packaging
- 50mg
- Price
- $210
- Updated
- 2021/12/16
- Product number
- FB109446
- Product name
- Bovine Pineal Antireproductive Tripeptide acetate salt H-Thr-Ser-Lys-OH acetate salt
- Packaging
- 100mg
- Price
- $365
- Updated
- 2021/12/16
- Product number
- orb364438
- Product name
- Bovine Pineal Antireproductive Peptide
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $552.5
- Updated
- 2021/12/16
- Product number
- BIO0000067
- Product name
- ANTIREPRODUCTIVE TRIPEPTIDE
- Purity
- 95.00%
- Packaging
- 50MG
- Price
- $709.46
- Updated
- 2021/12/16
BOVINE PINEAL ANTIREPRODUCTIVE TRIPEPTIDE ACETATE SALT Chemical Properties,Usage,Production
Uses
Threonyl-seryl-lysine, a bovine pineal antireproductive tripeptide, has antigonadotropic activity. Threonyl-seryl-lysine binds to luteinizing hormone-releasing hormone (LHRH) at a site comprised of LHRH 2-5[1][3].
Definition
ChEBI: Thr-Ser-Lys is an oligopeptide.
in vivo
Threonyl-seryl-lysine (175 ng, i.p.) reduces the 5-day compensatory ovarian hypertrophy in unilaterally ovariectomized (UO) mice[1].
Threonyl-seryl-lysine (1 or 5 μg, i.p.) delays vaginal opening time in female Charles River CD rats[2].
Threonyl-seryl-lysine (1 and 10 μg, s.c., for 15 days) increases the weight of ovaries and of adrenals in mice[4].
| Animal Model: | Unilaterally ovariectomized (UO) mice |
| Dosage: | 175 ng |
| Administration: | Intraperitoneal injection (i.p.) |
| Result: | Reduced serum follicle stimulating hormone (FSH) in UO mice. |
References
[1] Orts RJ, et al. Inhibitory properties of a bovine pineal tripeptide, threonylseryllysine, on serum follicle-stimulating hormone. Neuroendocrinology. 1980 Aug;31(2):92-5. DOI:10.1159/000123056
[2] Benson B. Bovine pineal tripeptide threonylseryllysine retards puberty in female rats. J Pineal Res. 1989;6(4):351-7. DOI:10.1111/j.1600-079x.1989.tb00431.x
[3] Root-Bernstein RS, et al. Bovine pineal antireproductive tripeptide binds to luteinizing hormone-releasing hormone: a model for peptide modulation by sequence specific peptide interactions? Brain Res Bull. 1986 Oct;17(4):519-28. DOI:10.1016/0361-9230(86)90219-4
[4] Vaughan M K, et al. Influence of Thr-Ser-Lys (TSL), a recently isolated pineal peptide, on ovarian and uterine weights and estrous cycles in mice, hamsters and rats. Pineal function (Mathews CD, Seamark RF, eds.), 1981: 165-172.
BOVINE PINEAL ANTIREPRODUCTIVE TRIPEPTIDE ACETATE SALT Preparation Products And Raw materials
Raw materials
Preparation Products
BOVINE PINEAL ANTIREPRODUCTIVE TRIPEPTIDE ACETATE SALT Suppliers
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