4-Methoxy-pyridin-2-ol

Product Name: 4-Methoxy-pyridin-2-ol
CAS No.: 52545-13-8
Chemical Name: 4-Methoxy-pyridin-2-ol
Synonyms: 4-Methoxypyridin-2-ol;4-METHOXY-2(1H)-PYRIDINONE;4-Methoxypyridi;Gimeraux impurities1;4-Methoxy-2-pyridone;4-Methoxypyridin-2(1H);4-methoxy-1H-pyridin-2-one;2(1H)-Pyridinone, 4-methoxy-;2(1H)-Pyridinone,4-methoxy-(9CI);4-Methoxy-1,2-dihydropyridin-2-one
CBNumber: CB51274315
Molecular Formula: C6H7NO2
Formula Weight: 125.13
MOL File: 52545-13-8.mol

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4-Methoxy-pyridin-2-ol Property

Melting point:: 101-102 °C
Boiling point:: 355.1±42.0 °C(Predicted)
Density: 1.16±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 11.08±0.10(Predicted)
Appearance: Yellow to brown Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC

Product number: M336563
Product name: 4-Methoxypyridin-2(1H)-one
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 074285
Product name: 4-Methoxy-2(1H)-pyridinone
Purity: 95+%
Packaging: 250mg
Price: $324
Updated: 2021/12/16

Matrix Scientific

Product number: 074285
Product name: 4-Methoxy-2(1H)-pyridinone
Purity: 95+%
Packaging: 1g
Price: $700
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0078937
Product name: 4-METHOXY-2(1H)-PYRIDINONE
Purity: 95.00%
Packaging: 250MG
Price: $933.24
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0078937
Product name: 4-METHOXY-2(1H)-PYRIDINONE
Purity: 95.00%
Packaging: 1G
Price: $1346.73
Updated: 2021/12/16

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4-Methoxy-pyridin-2-ol Chemical Properties,Usage,Production

Synthesis

1122-96-9

52545-13-8

General procedure for the synthesis of 4-methoxy-2-pyridone from 4-methoxypyridine-N-oxide: 4-methoxypyridine-N-oxide (1.5 g, 1.98 mmol) was dissolved in acetic anhydride (45 mL) and heated to reflux overnight under nitrogen protection. After completion of the reaction, it was cooled to room temperature and concentrated under reduced pressure to remove the acetic anhydride. The residue was diluted with distilled water (15 mL) and methanol (15 mL) and stirred overnight at room temperature. Subsequently, all volatiles were removed and the residue was purified by fast column chromatography (silica gel, dichloromethane/methanol gradient elution, 0 to 10% methanol) to afford 4-methoxy-2-pyridinone (1.1 g, 71% yield) as a brown solid.LC-MS (ESI): m/z [M + H]+ 126.0.

References

[1] Patent: WO2016/4272, 2016, A1. Location in patent: Paragraph 00591
[2] Journal of Organic Chemistry, 2005, vol. 70, # 16, p. 6204 - 6212
[3] Tetrahedron Letters, 1995, vol. 36, # 42, p. 7575 - 7578
[4] Journal of Organic Chemistry, 1999, vol. 64, # 3, p. 950 - 953
[5] Patent: WO2007/48070, 2007, A2. Location in patent: Page/Page column 111

4-Methoxy-pyridin-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Methoxy-pyridin-2-ol Suppliers

China 76 Europe 1 Germany 2 India 3 The Netherlands 1 United States 12 Global 95

Shanghai Boc Chemical Co.,Ltd

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Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
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Chimica Laboratories Co., Ltd

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Aloespharm Co., Ltd.

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Synchem OHG

Tel: +49 5662 408730
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Email: info@synchem.de
Country: Germany
ProdList: 4705
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View Lastest Price from 4-Methoxy-pyridin-2-ol manufacturers

Career Henan Chemical Co

Product: 2(1H)-Pyridinone,4-methoxy-(9CI) 52545-13-8
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-10

52545-13-8, 4-Methoxy-pyridin-2-olRelated Search:

RICININE 4-BENZYLOXY-2(1 H)-PYRIDONE 2-(4-METHOXY-2,3-DIHYDRO-FURO[2,3-B]QUINOLIN-2-YL)-PROPANE-1,2-DIOL 3-chloro-2,4-dimethoxypyridine penclomedine skimmianine N-(([(2-CHLORO-4-FLUOROBENZYL)OXY]IMINO)METHYL)-2-(4-FLUOROPHENOXY)-4-METHOXYNICOTINAMIDE AURORA KA-3527 N-(([(4-FLUOROBENZYL)OXY]IMINO)METHYL)-2-(4-FLUOROPHENOXY)-4-METHOXYNICOTINAMIDE N-(([(2,4-DICHLOROBENZYL)OXY]IMINO)METHYL)-2-(4-FLUOROPHENOXY)-4-METHOXYNICOTINAMIDE AURORA KA-4658 N-[(DIMETHYLAMINO)METHYLENE]-2-(4-FLUOROPHENOXY)-4-METHOXYNICOTINAMIDE AURORA KA-5064 2-(4-FLUOROPHENOXY)-3-(1H-1,2,4-TRIAZOL-3-YL)-4-PYRIDINYL METHYL ETHER AURORA KA-3496 2-(4-FLUOROPHENOXY)-4-METHOXYNICOTINAMIDE N-(([(2,6-DICHLOROBENZYL)OXY]IMINO)METHYL)-2-(4-FLUOROPHENOXY)-4-METHOXYNICOTINAMIDE 3-nitro-4-methoxypyridin-2-ol

2(1H)-Pyridinone,4-methoxy-(9CI)

4-METHOXY-2(1H)-PYRIDINONE

4-Methoxy-2-pyridone4-METHOXY-2(1H)-PYRIDINONE

4-Methoxy-2-pyridone

4-Methoxy-1,2-dihydropyridin-2-one

4-Methoxypyridin-2-ol

4-Methoxypyridin-2(1H)

4-Methoxypyridi

2(1H)-Pyridinone, 4-methoxy-

Gimeraux impurities1

4-methoxy-1H-pyridin-2-one

52545-13-8

PYRIDINE