4-Methoxy-pyridin-2-ol
- Product Name
- 4-Methoxy-pyridin-2-ol
- CAS No.
- 52545-13-8
- Chemical Name
- 4-Methoxy-pyridin-2-ol
- Synonyms
- 4-Methoxypyridin-2-ol;4-METHOXY-2(1H)-PYRIDINONE;4-Methoxypyridi;Gimeraux impurities1;4-Methoxy-2-pyridone;4-Methoxypyridin-2(1H);4-methoxy-1H-pyridin-2-one;2(1H)-Pyridinone, 4-methoxy-;2(1H)-Pyridinone,4-methoxy-(9CI);4-Methoxy-1,2-dihydropyridin-2-one
- CBNumber
- CB51274315
- Molecular Formula
- C6H7NO2
- Formula Weight
- 125.13
- MOL File
- 52545-13-8.mol
4-Methoxy-pyridin-2-ol Property
- Melting point:
- 101-102 °C
- Boiling point:
- 355.1±42.0 °C(Predicted)
- Density
- 1.16±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 11.08±0.10(Predicted)
- Appearance
- Yellow to brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M336563
- Product name
- 4-Methoxypyridin-2(1H)-one
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 074285
- Product name
- 4-Methoxy-2(1H)-pyridinone
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $324
- Updated
- 2021/12/16
- Product number
- 074285
- Product name
- 4-Methoxy-2(1H)-pyridinone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $700
- Updated
- 2021/12/16
- Product number
- CHM0078937
- Product name
- 4-METHOXY-2(1H)-PYRIDINONE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $933.24
- Updated
- 2021/12/16
- Product number
- CHM0078937
- Product name
- 4-METHOXY-2(1H)-PYRIDINONE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1346.73
- Updated
- 2021/12/16
4-Methoxy-pyridin-2-ol Chemical Properties,Usage,Production
Synthesis
1122-96-9
52545-13-8
General procedure for the synthesis of 4-methoxy-2-pyridone from 4-methoxypyridine-N-oxide: 4-methoxypyridine-N-oxide (1.5 g, 1.98 mmol) was dissolved in acetic anhydride (45 mL) and heated to reflux overnight under nitrogen protection. After completion of the reaction, it was cooled to room temperature and concentrated under reduced pressure to remove the acetic anhydride. The residue was diluted with distilled water (15 mL) and methanol (15 mL) and stirred overnight at room temperature. Subsequently, all volatiles were removed and the residue was purified by fast column chromatography (silica gel, dichloromethane/methanol gradient elution, 0 to 10% methanol) to afford 4-methoxy-2-pyridinone (1.1 g, 71% yield) as a brown solid.LC-MS (ESI): m/z [M + H]+ 126.0.
References
[1] Patent: WO2016/4272, 2016, A1. Location in patent: Paragraph 00591
[2] Journal of Organic Chemistry, 2005, vol. 70, # 16, p. 6204 - 6212
[3] Tetrahedron Letters, 1995, vol. 36, # 42, p. 7575 - 7578
[4] Journal of Organic Chemistry, 1999, vol. 64, # 3, p. 950 - 953
[5] Patent: WO2007/48070, 2007, A2. Location in patent: Page/Page column 111
4-Methoxy-pyridin-2-ol Preparation Products And Raw materials
Raw materials
Preparation Products
4-Methoxy-pyridin-2-ol Suppliers
- Tel
- --
- Fax
- --
- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
View Lastest Price from 4-Methoxy-pyridin-2-ol manufacturers
- Product
- 2(1H)-Pyridinone,4-methoxy-(9CI) 52545-13-8
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-10