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2-COUMARANONE

Description Reference
Product Name
2-COUMARANONE
CAS No.
553-86-6
Chemical Name
2-COUMARANONE
Synonyms
BENZOFURANONE;2-Cumaranon;2-Coumaronone;2-COUMARANONE;ISOCOUMARANONE;2H-BENZOFURANONE;BENZOFURAN-2-ONE;2-Coumaranone,99%;2-Coumaranone,97%;2-Coumaranone 97%
CBNumber
CB5131550
Molecular Formula
C8H6O2
Formula Weight
134.13
MOL File
553-86-6.mol
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2-COUMARANONE Property

Melting point:
49-51 °C(lit.)
Boiling point:
248-250 °C(lit.)
Density 
1,22 g/cm3
vapor pressure 
0.027-0.24Pa at 10-30℃
refractive index 
1.4800 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: soluble3.8g/L at 30°C
form 
Crystalline Powder or Crystals
color 
White to yellow-orange
BRN 
114689
InChIKey
ACZGCWSMSTYWDQ-UHFFFAOYSA-N
LogP
1.347
Surface tension
63.8mN/m at 1g/L and 20℃
CAS DataBase Reference
553-86-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38-43-36/38
Safety Statements 
24/25-36-26-36/37
WGK Germany 
3
HS Code 
29322090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
124591
Product name
2-Coumaranone
Purity
97%
Packaging
1g
Price
$46
Updated
2024/03/01
Sigma-Aldrich
Product number
124591
Product name
2-Coumaranone
Purity
97%
Packaging
10g
Price
$199
Updated
2024/03/01
TCI Chemical
Product number
C1445
Product name
2-Coumaranone
Purity
>98.0%(GC)
Packaging
5g
Price
$64
Updated
2024/03/01
TCI Chemical
Product number
C1445
Product name
2-Coumaranone
Purity
>98.0%(GC)
Packaging
25g
Price
$185
Updated
2024/03/01
Alfa Aesar
Product number
A18617
Product name
2-Coumaranone, 99%
Packaging
1g
Price
$39.65
Updated
2024/03/01
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2-COUMARANONE Chemical Properties,Usage,Production

Description

2-Coumaranone (also named as Isophthalide, 3H-benzofuran-2-one) belongs to a class of organic compounds named as benzofuranones which exhibits mutagenic and carcinogenic activity. 2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland and as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures.

Reference

Y. S. Priya, K. Ramachandra Rao, P. V. Chalapathi, M. Satyavani, A. Veeraiah, Vibrational and UV spectroscopic studies of 2-coumaranone by experimental and density functional theory calculations, Journal of Molecular Structure, 2017, vol. 1144, pp. 535-544

Chemical Properties

WHITE TO LIGHT YELLOW CRYSTALLINE POWDER

Uses

2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland. It was employed as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures.

Synthesis Reference(s)

The Journal of Organic Chemistry, 47, p. 2491, 1982 DOI: 10.1021/jo00133a055

2-COUMARANONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-COUMARANONE Suppliers

Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-63315541 13323832564
Fax
QQ:3001332135
Email
3001332135@qq.com
Country
China
ProdList
9880
Advantage
58
Hangzhou Benoy Chemical Co., Ltd.
Tel
17342059697
Fax
QQ:2710089141
Email
sales@benoychem.com
Country
China
ProdList
389
Advantage
58
Changzhou Xintong Chemical Co., Ltd.
Tel
0519-82319070 18006146622
Email
493379833@qq.com
Country
China
ProdList
171
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
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View Lastest Price from 2-COUMARANONE manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
2-COUMARANONE 553-86-6
Price
US $1.00/PCS
Min. Order
1PCS
Purity
99%
Supply Ability
10 mt
Release date
2024-10-28
airuikechemical co., ltd.
Product
2-COUMARANONE 553-86-6
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-10
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Coumaranone 553-86-6
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-13

553-86-6, 2-COUMARANONERelated Search:


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