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2-COUMARANONE

Description Reference
Product Name
2-COUMARANONE
CAS No.
553-86-6
Chemical Name
2-COUMARANONE
Synonyms
BENZOFURANONE;2-Cumaranon;2-Coumaronone;2-COUMARANONE;ISOCOUMARANONE;2H-BENZOFURANONE;BENZOFURAN-2-ONE;2-Coumaranone,99%;2-Coumaranone,97%;2-Coumaranone 97%
CBNumber
CB5131550
Molecular Formula
C8H6O2
Formula Weight
134.13
MOL File
553-86-6.mol
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2-COUMARANONE Property

Melting point:
49-51 °C(lit.)
Boiling point:
248-250 °C(lit.)
Density 
1,22 g/cm3
vapor pressure 
0.027-0.24Pa at 10-30℃
refractive index 
1.4800 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: soluble3.8g/L at 30°C
form 
Crystalline Powder or Crystals
color 
White to yellow-orange
BRN 
114689
InChIKey
ACZGCWSMSTYWDQ-UHFFFAOYSA-N
LogP
1.347
Surface tension
63.8mN/m at 1g/L and 20℃
CAS DataBase Reference
553-86-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38-43-36/38
Safety Statements 
24/25-36-26-36/37
WGK Germany 
3
HS Code 
29322090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
124591
Product name
2-Coumaranone
Purity
97%
Packaging
1g
Price
$46
Updated
2024/03/01
Sigma-Aldrich
Product number
124591
Product name
2-Coumaranone
Purity
97%
Packaging
10g
Price
$199
Updated
2024/03/01
TCI Chemical
Product number
C1445
Product name
2-Coumaranone
Purity
>98.0%(GC)
Packaging
5g
Price
$64
Updated
2024/03/01
TCI Chemical
Product number
C1445
Product name
2-Coumaranone
Purity
>98.0%(GC)
Packaging
25g
Price
$185
Updated
2024/03/01
Alfa Aesar
Product number
A18617
Product name
2-Coumaranone, 99%
Packaging
1g
Price
$39.65
Updated
2024/03/01
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2-COUMARANONE Chemical Properties,Usage,Production

Description

2-Coumaranone (also named as Isophthalide, 3H-benzofuran-2-one) belongs to a class of organic compounds named as benzofuranones which exhibits mutagenic and carcinogenic activity. 2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland and as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures.

Reference

Y. S. Priya, K. Ramachandra Rao, P. V. Chalapathi, M. Satyavani, A. Veeraiah, Vibrational and UV spectroscopic studies of 2-coumaranone by experimental and density functional theory calculations, Journal of Molecular Structure, 2017, vol. 1144, pp. 535-544

Chemical Properties

WHITE TO LIGHT YELLOW CRYSTALLINE POWDER

Uses

2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland. It was employed as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures.

Synthesis Reference(s)

The Journal of Organic Chemistry, 47, p. 2491, 1982 DOI: 10.1021/jo00133a055

2-COUMARANONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-COUMARANONE Suppliers

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View Lastest Price from 2-COUMARANONE manufacturers

airuikechemical co., ltd.
Product
2-COUMARANONE 553-86-6
Price
US $0.00-0.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-10
Hebei Duling International Trade Co. LTD
Product
2-COUMARANONE 553-86-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99.8%
Supply Ability
20tons
Release date
2023-03-21
Hebei Guanlang Biotechnology Co,.LTD
Product
2-Coumaranone 553-86-6
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2023-03-17

553-86-6, 2-COUMARANONERelated Search:

3-(Methoxymethylene)-2(3H)-benzofuranone FLUORESCEINYL GABAZINE, BROMIDE 5-HYDROXY-2-COUMARANONE Amolanone 2-COUMARANONE 6-HYDROXY-3-COUMARANONE BENZOFURAN-3(2H)-ONE, 3-COUMARANONE,COUMARANONE,3-Coumaranone(3(2H)-Benzofuranone),3-COUMARANONE 2H-BEZOFURAN-3-ONE 3-COUMARANONE 2-Carboethoxy-3-coumaranone,2-ETHOXYCARBONYL-3-COUMARANONE ETHOFUMESATE-2-KETO 2,3-DIOXY-6-METHOXYBENZOFURAN NAPHTHO[2,1-B]FURAN-2(1H)-ONE 4-SPIRO-[3-COUMARANONE] PIPERIDINE HYDROCHLORIDE OXYPEUCEDANIN 3-BROMO-2-COUMARANONE Clofurac AKOS BC-0022 5-Benzofuranacetic acid, 2,3-dihydro-2-oxo-3-phenyl-, methyl ester

  • 1-Benzofuran-2(3H)-one
  • 2-Coumaronone
  • 2,3-dihydrobenzofuran-2-one
  • Benzo[b]furan-2(3H)-one
  • BENZOFURAN-2[3H]-ONE
  • 2H-BENZOFURANONE
  • 2-COUMARANONE
  • 2(3H)-BENZOFURANONE
  • 2,3-DIHYDROBENZO[B]FURAN-2-ONE
  • 3H-BENZOFURAN-2-ONE
  • 3H-Benzofuran-2-one~2,3-Dihydrobenzofuran-2-one
  • GIRARD'S REAGENT P 98%
  • 2-Coumaranone,99%
  • 2-Cumaranon
  • BENZOFURAN-2-ONE
  • BENZOFURANONE
  • ISOCOUMARANONE
  • 2-Coumaranone,97%
  • Benzofuran-2(2H)-one
  • 2(3H)-Benzofuranone Isocoumaranone
  • 2-Coumaranone 97%
  • (3H)-benzofuran-2-on
  • 2-Coumaranone &gt
  • 2-COUMARANONE USP/EP/BP
  • Azoxystobin intermediate
  • 553-86-6
  • 533-86-6
  • Building Blocks
  • Benzofurans
  • Heterocyclic Building Blocks
  • Benzofurans
  • Building Blocks
  • Heterocyclic Building Blocks