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CKS 17

Product Name
CKS 17
CAS No.
99273-04-8
Chemical Name
CKS 17
Synonyms
Aids002113;Aids-002113;Lqnrrgldllflkeggl-bsa;CKS-17 (dimer), MN10021 - 1 mg;CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH;Leu-Gln-Asn-Arg-arg-Gly-Leu-Asp-Leu-leu-Phe-Leu-Lys-Glu-Gly-gly-Leu linked to bsa;L-Leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl-L-leucine;L-Leucine, L-leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl-;L-Leucine, L-leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-.alpha.-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-.alpha.-glutamylglycylglycyl-
CBNumber
CB51317175
Molecular Formula
C87H148N26O24
Formula Weight
1942.28
MOL File
99273-04-8.mol
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CKS 17 Property

Density 
1.41±0.1 g/cm3(Predicted)
form 
Solid
pka
3.40±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FC110174
Product name
CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH
Packaging
250ug
Price
$105
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC110174
Product name
CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH
Packaging
500ug
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC110174
Product name
CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH
Packaging
1mg
Price
$319
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC110174
Product name
CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH
Packaging
2mg
Price
$542
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001110
Product name
CKS-17
Purity
95.00%
Packaging
0.5MG
Price
$594.25
Updated
2021/12/16
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CKS 17 Chemical Properties,Usage,Production

Uses

CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions[1][2][3].

in vivo

CKS-17 (10 μM; i.d.; B6AF1 mice and C57BL/6J mice) inhibits delayed-type hypersensitivity (DTH) reactions to sheep erythrocytes in the feet of mice[2].

Animal Model:B6AF1 mice and C57BL/6J mice with DTH models[2]
Dosage:10 μM
Administration:Intradermal injection, into the right hind footpad
Result:Had a transient depressive effect on DTH reaction.

References

[1] Haraguchi S, et, al. Induction of intracellular cAMP by a synthetic retroviral envelope peptide: a possible mechanism of immunopathogenesis in retroviral infections. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5568-71. DOI:10.1073/pnas.92.12.5568
[2] Nelson M, et, al. Effects of CKS-17, a synthetic retroviral envelope peptide, on cell-mediated immunity in vivo: immunosuppression, immunogenicity, and relation to immunosuppressive tumor products. Cancer Immunol Immunother. 1989;30(2):113-8. DOI:10.1007/BF01665962
[3] Nelson M, et, al. Inhibition of interleukin-2 production by tumor cell products and by CKS-17, a synthetic retroviral envelope peptide. Cancer Immunol Immunother. 1990;30(6):331-41. DOI:10.1007/BF01786882

CKS 17 Preparation Products And Raw materials

Raw materials

Preparation Products

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CKS 17 Suppliers

China 38 United Kingdom 1 Global 39
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
Nanjing Leon Biological Technology Co., Ltd.
Tel
17705183659
Fax
84523390
Email
sales@njleonbiotech.com
Country
China
ProdList
5501
Advantage
55
Nanjing Peptide Biotech Ltd.
Tel
025-58361106-805 15951641583
Fax
025-58361106-806
Email
zhao.xu@njpeptide.com
Country
China
ProdList
9979
Advantage
55
Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4802
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
0571-88211921
Email
sales1@gotopbio.com
Country
CHINA
ProdList
2609
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Nanjing chengqimei Biotechnology Co., Ltd
Tel
19850819832
Email
2173594524@qq.com
Country
China
ProdList
2638
Advantage
58
Nanjing TGpeptide Biotechnology Co.,Ltd.
Tel
18115476705
Email
sales@tgpeptide.com
Country
China
ProdList
3058
Advantage
58
Hangzhou Go Top Peptide Biotech
Tel
15397062932
Email
sales1@gotopbio.com
Country
China
ProdList
2923
Advantage
58
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View Lastest Price from CKS 17 manufacturers

Career Henan Chemica Co
Product
CKS 17 99273-04-8
Price
US $7.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2020-10-28

99273-04-8, CKS 17Related Search:

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