CKS 17

Product Name: CKS 17
CAS No.: 99273-04-8
Chemical Name: CKS 17
Synonyms: Aids002113;Aids-002113;Lqnrrgldllflkeggl-bsa;CKS-17 (dimer), MN10021 - 1 mg;CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH;Leu-Gln-Asn-Arg-arg-Gly-Leu-Asp-Leu-leu-Phe-Leu-Lys-Glu-Gly-gly-Leu linked to bsa;L-Leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl-L-leucine;L-Leucine, L-leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl-;L-Leucine, L-leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-.alpha.-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-.alpha.-glutamylglycylglycyl-
CBNumber: CB51317175
Molecular Formula: C87H148N26O24
Formula Weight: 1942.28
MOL File: 99273-04-8.mol

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CKS 17 Property

Density: 1.41±0.1 g/cm3(Predicted)
form: Solid
pka: 3.40±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FC110174
Product name: CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH
Packaging: 250ug
Price: $105
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC110174
Product name: CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH
Packaging: 500ug
Price: $185
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC110174
Product name: CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH
Packaging: 1mg
Price: $319
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC110174
Product name: CKS-17 H-Leu-Gln-Asn-Arg-Arg-Gly-Leu-Asp-Leu-Leu-Phe-Leu-Lys-Glu-Gly-Gly-Leu-OH
Packaging: 2mg
Price: $542
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0001110
Product name: CKS-17
Purity: 95.00%
Packaging: 0.5MG
Price: $594.25
Updated: 2021/12/16

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CKS 17 Chemical Properties,Usage,Production

Uses

CKS-17 is a synthetic retroviral envelope peptide. CKS-17 has the highly conserved amino acid sequences occurring within the transmembrane envelope protein of many animal and human retroviruses. CKS-17 acts as an immunomodulatory epitope and exhibits suppressive properties for numerous immune functions[1][2][3].

in vivo

CKS-17 (10 μM; i.d.; B6AF1 mice and C57BL/6J mice) inhibits delayed-type hypersensitivity (DTH) reactions to sheep erythrocytes in the feet of mice^[2].

Animal Model:	B6AF1 mice and C57BL/6J mice with DTH models^[2]
Dosage:	10 μM
Administration:	Intradermal injection, into the right hind footpad
Result:	Had a transient depressive effect on DTH reaction.

References

[1] Haraguchi S, et, al. Induction of intracellular cAMP by a synthetic retroviral envelope peptide: a possible mechanism of immunopathogenesis in retroviral infections. Proc Natl Acad Sci U S A. 1995 Jun 6;92(12):5568-71. DOI:10.1073/pnas.92.12.5568
[2] Nelson M, et, al. Effects of CKS-17, a synthetic retroviral envelope peptide, on cell-mediated immunity in vivo: immunosuppression, immunogenicity, and relation to immunosuppressive tumor products. Cancer Immunol Immunother. 1989;30(2):113-8. DOI:10.1007/BF01665962
[3] Nelson M, et, al. Inhibition of interleukin-2 production by tumor cell products and by CKS-17, a synthetic retroviral envelope peptide. Cancer Immunol Immunother. 1990;30(6):331-41. DOI:10.1007/BF01786882

CKS 17 Preparation Products And Raw materials

Raw materials

Preparation Products

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CKS 17 Suppliers

China 38 United Kingdom 1 Global 39

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View Lastest Price from CKS 17 manufacturers

Career Henan Chemica Co

Product: CKS 17 99273-04-8
Price: US $7.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 100kg
Release date: 2020-10-28

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L-Leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl-L-leucine

L-Leucine, L-leucyl-L-glutaminyl-L-asparaginyl-L-arginyl-L-arginylglycyl-L-leucyl-L-α-aspartyl-L-leucyl-L-leucyl-L-phenylalanyl-L-leucyl-L-lysyl-L-α-glutamylglycylglycyl-

CKS-17 (dimer), MN10021 - 1 mg

99273-04-8