glycyl-arginyl-glycyl-aspartyl-seryl-proline
- Product Name
- glycyl-arginyl-glycyl-aspartyl-seryl-proline
- CAS No.
- 91037-75-1
- Chemical Name
- glycyl-arginyl-glycyl-aspartyl-seryl-proline
- Synonyms
- glycyl-arginyl-glycyl-aspartyl-seryl-proline;Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline;L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-
- CBNumber
- CB51329233
- Molecular Formula
- C22H37N9O10
- Formula Weight
- 587.58
- MOL File
- 91037-75-1.mol
glycyl-arginyl-glycyl-aspartyl-seryl-proline Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
- Sequence
- Gly-Arg-Gly-Asp-Ser-Pro
N-Bromosuccinimide Price
- Product number
- CS-7039
- Product name
- GRGDSP
- Packaging
- 5mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- CS-7039
- Product name
- GRGDSP
- Packaging
- 10mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- CS-7039
- Product name
- GRGDSP
- Packaging
- 25mg
- Price
- $640
- Updated
- 2021/12/16
glycyl-arginyl-glycyl-aspartyl-seryl-proline Chemical Properties,Usage,Production
Uses
GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
Biological Activity
GRGDSP is a synthetic linear RGD peptide that is an integrin inhibitor.
in vitro
It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly -Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization.
p>
target
Integrin
References
[1] Qian J, et al. Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model. World J Gastroenterol. 2016 Jun 7;22(21):5042-9. DOI:10.3748/wjg.v22.i21.5042
[2] Patel S, et al. Regulation of endothelial cell function by GRGDSP peptide grafted on interpenetrating polymers. J Biomed Mater Res A. 2007 Nov;83(2):423-33. DOI:10.1002/jbm.a.31320
glycyl-arginyl-glycyl-aspartyl-seryl-proline Preparation Products And Raw materials
Raw materials
Preparation Products
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