paraherquamide

Product Name: paraherquamide
CAS No.: 77392-58-6
Chemical Name: paraherquamide
Synonyms: VM 29919;paraherquamide;(-)-Paraherquamide A;Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizine]-9,10'(10H)-dione, 2',3',8'a,9'-tetrahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-
CBNumber: CB51336725
Molecular Formula: C28H35N3O5
Formula Weight: 493.59
MOL File: 77392-58-6.mol

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paraherquamide Property

Melting point:: 244-247° (dec)
alpha: D22 -28° (c = 0.43 in methanol)
storage temp.: Store at -20°C
solubility: DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form: White to off-white powder.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26685
Product name: Paraherquamide A
Packaging: 1mg
Price: $347
Updated: 2024/03/01

Cayman Chemical

Product number: 26685
Product name: Paraherquamide A
Packaging: 5mg
Price: $1210
Updated: 2024/03/01

TRC

Product number: P193278
Product name: ParaherquamideA
Packaging: 0.5mg
Price: $560
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0004348
Product name: PARAHERQUAMIDE A
Purity: 95.00%
Packaging: 1MG
Price: $538.65
Updated: 2021/12/16

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paraherquamide Chemical Properties,Usage,Production

Description

Paraherquamide A is a mycotoxin anthelmintic originally isolated from P. paraherquei. It binds to acetylcholine receptors (IC₅₀ = 0.5 nM for head homogenates of M. domestica) and acts as an antagonist. Paraherquamide A is toxic to C. elegans (LD₅₀ = 2.5 μg/ml) and effective against T. colubriformis infection in gerbils when used at doses ranging from 0.39 to 200 mg/kg. It is toxic to mice (LD₅₀ = 14.9 mg/kg).

Uses

Paraherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins. Subsequent research identified a potent, non-toxic paralysis of nematodes which led to the metabolite's development as a candidate anthelmintic. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors.

Uses

Paraherquamide A is a selective, competitive, cholinergic antagonist.

paraherquamide Preparation Products And Raw materials

Raw materials

Preparation Products

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paraherquamide Suppliers

China 13 India 1 United Kingdom 1 United States 4 Global 19

Shanghai EFE Biological Technology Co., Ltd.

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Lynnchem

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Shenzhen Polymeri Biochemical Technology Co., Ltd.

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Energy Chemical

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Hangzhou Verychem Science And Technology Co.Ltd

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Hangzhou Verychem Science And Technology Co., Ltd

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77392-58-6, paraherquamideRelated Search:

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paraherquamide

VM 29919

Spiro[4H,8H-[1,4]dioxepino[2,3-g]indole-8,7'(8'H)-[5H,6H-5a,9a](iminomethano)[1H]cyclopent[f]indolizine]-9,10'(10H)-dione, 2',3',8'a,9'-tetrahydro-1'-hydroxy-1',4,4,8',8',11'-hexamethyl-, (1'R,5'aS,7'R,8'aS,9'aR)-

(-)-Paraherquamide A

77392-58-6