scyliorhinin II
- Product Name
- scyliorhinin II
- CAS No.
- 112748-19-3
- Chemical Name
- scyliorhinin II
- Synonyms
- PubChem ID: 101569057;L-Methioninamide, L-seryl-L-prolyl-L-seryl-L-asparaginyl-L-seryl-L-lysyl-L-cysteinyl-L-prolyl-L-α-aspartylglycyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-valylglycyl-L-leucyl-, cyclic (7→13)-disulfide
- CBNumber
- CB51347972
- Molecular Formula
- C77H119N21O26S3
- Formula Weight
- 1851.09
- MOL File
- 112748-19-3.mol
scyliorhinin II Property
- Boiling point:
- 2202.7±65.0 °C(Predicted)
- Density
- 1.47±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 4.01±0.10(Predicted)
- Sequence
- Ser-Pro-Ser-Asn-Ser-Lys-Cys-Pro-Asp-Gly-Pro-Asp-Cys-Phe-Val-Gly-Leu-Met-NH2
N-Bromosuccinimide Price
- Product number
- CS-0045214
- Product name
- ScyliorhininII
- Packaging
- 1mg
- Price
- $120
- Updated
- 2021/12/16
- Product number
- CS-0045214
- Product name
- ScyliorhininII
- Packaging
- 5mg
- Price
- $260
- Updated
- 2021/12/16
- Product number
- CS-0045214
- Product name
- ScyliorhininII
- Packaging
- 10mg
- Price
- $420
- Updated
- 2021/12/16
- Product number
- PEP0009221
- Product name
- SCYLIORHININ II AMIDE-DOGFISH
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $641.03
- Updated
- 2021/12/16
- Product number
- CS-0045214
- Product name
- ScyliorhininII
- Packaging
- 25mg
- Price
- $840
- Updated
- 2021/12/16
scyliorhinin II Chemical Properties,Usage,Production
Uses
Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.
in vivo
Scyliorhinin II produces potent, dose-related reciprocal hindlimb scratching about equipotently with an ED50 of 0.08 nmol via intracerebroventricularly (i.c.v.) administration in mice[2].
References
[1] Buck SH, et al. The dogfish peptides scyliorhinin I and scyliorhinin II bind with differential selectivity to mammalian tachykinin receptors. Eur J Pharmacol. 1987 Nov 24;144(1):109-11. DOI:10.1016/0014-2999(87)90017-3
[2] Raffa RB, et al. Scyliorhinin-I and -II induce reciprocal hindlimb scratching in mice: differentiation of spinal and supraspinal neurokinin receptors in vivo. Neurosci Lett. 1993 Aug 6;158(1):87-91. DOI:10.1016/0304-3940(93)90619-v
scyliorhinin II Preparation Products And Raw materials
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