LAVENDUSTIN C

ChemicalBook > CAS DataBase List > LAVENDUSTIN C

Product Name: LAVENDUSTIN C
CAS No.: 125697-93-0
Chemical Name: LAVENDUSTIN C
Synonyms: HDBA;COMPOUND 5;NSC 666251;LAVENDUSTIN C;Lavendustin C (HDBA);5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID;5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID;5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID;N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID;2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid
CBNumber: CB5135705
Molecular Formula: C14H13NO5
Formula Weight: 275.26
MOL File: 125697-93-0.mol

Less

LAVENDUSTIN C Property

Melting point:: 193-195°C dec.
Boiling point:: 597.5±50.0 °C(Predicted)
Density: 1.551±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO: soluble
form: solid
pka: 2.32±0.10(Predicted)
color: Light Beige to Brown
Stability:: Hygroscopic

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 3-10

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 10010329
Product name: Lavendustin C
Purity: ≥98%
Packaging: 1mg
Price: $26
Updated: 2024/03/01

Cayman Chemical

Product number: 10010329
Product name: Lavendustin C
Purity: ≥98%
Packaging: 5mg
Price: $111
Updated: 2024/03/01

Cayman Chemical

Product number: 10010329
Product name: Lavendustin C
Purity: ≥98%
Packaging: 10mg
Price: $195
Updated: 2024/03/01

Cayman Chemical

Product number: 10010329
Product name: Lavendustin C
Purity: ≥98%
Packaging: 50mg
Price: $849
Updated: 2024/03/01

TRC

Product number: D452000
Product name: 5-(2,5-Dihydroxybenzylamino)-2-hydroxybenzoicAcid
Packaging: 25mg
Price: $410
Updated: 2021/12/16

Less

LAVENDUSTIN C Chemical Properties,Usage,Production

Description

Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC₅₀ value of 0.012 μM. Lavendustin C also inhibits pp60^c-src(+) kinase and Ca²⁺ calmodulin-dependent kinase II with IC₅₀ values of 0.5 and 0.2 μM, respectively. At a concentration of 10-150 μM, lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.

Chemical Properties

Brown Solid

Uses

Shows potent tyrosine kinase inhibitory activity.

Definition

ChEBI: 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid is an aromatic amine.

LAVENDUSTIN C Preparation Products And Raw materials

Raw materials

Preparation Products

Less

LAVENDUSTIN C Suppliers

Canada 1 China 62 Germany 2 India 1 South Korea 1 Switzerland 2 United Kingdom 3 United States 13 USA 1 Global 86

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shanghai JiYi Biotechnology Co. Ltd.

Tel: 13621943973
Fax: -
Email: sales@shjiyipharmatech.com
Country: China
ProdList: 1166
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8012
Advantage: 62

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

Twochem Co.Ltd.

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 1788
Advantage: 58

Jinan Kabotang Biological Technology Co.,Ltd.

Tel: 0531-61320525 15866703830
Email: 495745175@qq.com
Country: China
ProdList: 6897
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3253
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57423
Advantage: 58

Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

Tel: 18081075745
Email: chemflowtech@sina.com
Country: China
ProdList: 1886
Advantage: 58

Jinan Carbotang Biotech Co.,Ltd.

Tel: +8615866703830
Email: figo.gao@foxmail.com
Country: China
ProdList: 8497
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973; 13621943973
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1111
Advantage: 58

Advanced chemblocks inc

Tel: 650-6922368
Email: sales@achemblock.com
Country: China
ProdList: 2992
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44806
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Krain Pharmaceutical Technology CO.,Ltd

Tel: 18252089365
Email: Krain_kerun@163.com
Country: China
ProdList: 2620
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6753
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24644
Advantage: 58

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 9470
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 17691182729 15529505138
Email: 1021@dideu.com
Country: China
ProdList: 9972
Advantage: 58

Nanjing Tengyi Biotechnology Co., Ltd

Tel: 025-58851786 17714337195
Email: sales@tybiochem.com
Country: China
ProdList: 6813
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29979
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12005
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 32957
Advantage: 60

ShenZhen Trendseen Biological Technology Co.,Ltd.

Tel: 13417589054
Email: trendseenbio@gmail.com
Country: China
ProdList: 11681
Advantage: 58

Hebei Weibang Biotechnology Co., Ltd

Tel: +8617732866630
Email: bess@weibangbio.com
Country: China
ProdList: 18150
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Beijing Taize Jiaye Technology Development Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6050
Advantage: 58

Beijing Sizhengbai Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: marketing@4abio.com
Country: CHINA
ProdList: 6401
Advantage: 58

Shanghai Haoran Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 470003480@QQ.COM
Country: CHINA
ProdList: 6955
Advantage: 58

Beijing Dongge Boye Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1861586486@qq.com
Country: CHINA
ProdList: 6648
Advantage: 58

Beijing Bolide Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1985563437@qq.com
Country: CHINA
ProdList: 6158
Advantage: 58

Shenzhen Xinbosheng Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: service@neobioscience.com
Country: CHINA
ProdList: 6151
Advantage: 58

Morning Student Science and Technology (Guangzhou) Co., Ltd.

Tel: --
Fax: --
Email: chenxue_gz@163.com
Country: CHINA
ProdList: 6600
Advantage: 58

Xiamen Research Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1562893815@qq.com
Country: CHINA
ProdList: 6936
Advantage: 58

Beijing Lebo Biotechnology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6057
Advantage: 58

Beijing Bai Ao Si Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: yangmei@bioneeds.net
Country: CHINA
ProdList: 6999
Advantage: 58

Shanghai Minmin Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1914109725@qq.com
Country: CHINA
ProdList: 6518
Advantage: 58

Beijing Baiao Innovation Technology Co., Ltd.

Tel: --
Fax: --
Email: 3007606172@qq.com
Country: CHINA
ProdList: 6002
Advantage: 58

Beijing Fubo Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: info@f-biology.com
Country: CHINA
ProdList: 6025
Advantage: 58

Shanghai Weiwei Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: sales@wheybio.com
Country: CHINA
ProdList: 4398
Advantage: 58

Shanghai Jingke Chemical Technology Co., Ltd.

Tel: --
Fax: --
Email: jingkehuaxue@163.com
Country: CHINA
ProdList: 6972
Advantage: 58

Nanjing Sai Ruirui Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: sales@shrbio.com
Country: CHINA
ProdList: 6871
Advantage: 58

125697-93-0, LAVENDUSTIN CRelated Search:

5-Aminosalicylic acid Salicylic acid Lavendustin C Analog, Methyl-4-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoate,LAVENDUSTIN C ANALOG LAVENDUSTIN B lavendustin C6 5-BENZYL-2-FURALDEHYDE LAVENDUSTIN A METHYL ESTER LAVENDUSTIN C LAVENDUSTIN C METHYL ESTER LAVENDUSTIN A

2-HYDROXY-5-(2,5-DIHYDROXYBENZYLAMINO)BENZOIC ACID

[2-HYDROXY-5-[N-(2',5'-DIHYDROXYBENZYL)AMINO]BENZOIC ACID

5-(2,5-DIHYDROXYBENZYLAMINO)-2-HYDROXYBENZOIC ACID

5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID

5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID

5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID

HDBA

COMPOUND 5

LAVENDUSTIN C

N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID

2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid

Compound 5, HDBA, N-(2μ,5μ-Dihydroxybenzyl)-5-aminosalicylic acid, [2-Hydroxy-5-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoic acid

5-(2,5-Dihydroxybenzylamino)salicylic acid, N-(2,5-Dihydroxybenzyl)-5-aminosalicylic acid

5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid

5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxy-benzoic acid

NSC 666251

N-(2-((2-((4Z,7Z,10Z,13Z,16Z,19Z)-DOCOSA-4,7,10,13,16,19-HEXAENAMIDO)ETHYL)DISULFANYL)-2-METHYLPROPYL)NICOTINAMIDE

Lavendustin C (HDBA)

Benzoic acid, 5-[[(2,5-dihydroxyphenyl)methyl]amino]-2-hydroxy-

HER1,ErbB-1,EGFR,inhibit,Inhibitor,Calmodulin-dependent protein kinases,calmodulin-dependent,Src,lavendustin C,pp60,CaMK,Ca2+,Epidermal growth factor receptor,tyrosine,kinase,Calmodulin-dependent kinases

125697-93-0

Chelators

Cell Signaling and Neuroscience

Receptor Tyrosine Kinase Inhibitors

Tyrosine Kinase (TK)

Kinase/Phosphatase Biology

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Type

Enzyme Inhibitors

Cell Biology

BioChemical

Biochemicals and Reagents

Other enzyme inhibitors and activators

All Inhibitors

Inhibitors

Tyrosine Kinase Inhibitors