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LAVENDUSTIN C

Product Name
LAVENDUSTIN C
CAS No.
125697-93-0
Chemical Name
LAVENDUSTIN C
Synonyms
HDBA;COMPOUND 5;NSC 666251;LAVENDUSTIN C;Lavendustin C (HDBA);5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID;5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID;5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID;N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID;2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid
CBNumber
CB5135705
Molecular Formula
C14H13NO5
Formula Weight
275.26
MOL File
125697-93-0.mol
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LAVENDUSTIN C Property

Melting point:
193-195°C dec.
Boiling point:
597.5±50.0 °C(Predicted)
Density 
1.551±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: soluble
form 
solid
pka
2.32±0.10(Predicted)
color 
Light Beige to Brown
Stability:
Hygroscopic
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
3-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10010329
Product name
Lavendustin C
Purity
≥98%
Packaging
1mg
Price
$26
Updated
2024/03/01
Cayman Chemical
Product number
10010329
Product name
Lavendustin C
Purity
≥98%
Packaging
5mg
Price
$111
Updated
2024/03/01
Cayman Chemical
Product number
10010329
Product name
Lavendustin C
Purity
≥98%
Packaging
10mg
Price
$195
Updated
2024/03/01
Cayman Chemical
Product number
10010329
Product name
Lavendustin C
Purity
≥98%
Packaging
50mg
Price
$849
Updated
2024/03/01
TRC
Product number
D452000
Product name
5-(2,5-Dihydroxybenzylamino)-2-hydroxybenzoicAcid
Packaging
25mg
Price
$410
Updated
2021/12/16
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LAVENDUSTIN C Chemical Properties,Usage,Production

Description

Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 μM. Lavendustin C also inhibits pp60c-src(+) kinase and Ca2+ calmodulin-dependent kinase II with IC50 values of 0.5 and 0.2 μM, respectively. At a concentration of 10-150 μM, lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.

Chemical Properties

Brown Solid

Uses

Shows potent tyrosine kinase inhibitory activity.

Definition

ChEBI: 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid is an aromatic amine.

LAVENDUSTIN C Preparation Products And Raw materials

Raw materials

Preparation Products

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LAVENDUSTIN C Suppliers

Canada 1 China 62 Germany 2 India 1 South Korea 1 Switzerland 2 United Kingdom 3 United States 13 USA 1 Global 86

125697-93-0, LAVENDUSTIN CRelated Search:

5-Aminosalicylic acid Salicylic acid Lavendustin C Analog, Methyl-4-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoate,LAVENDUSTIN C ANALOG LAVENDUSTIN B lavendustin C6 5-BENZYL-2-FURALDEHYDE LAVENDUSTIN A METHYL ESTER LAVENDUSTIN C LAVENDUSTIN C METHYL ESTER LAVENDUSTIN A

  • 2-HYDROXY-5-(2,5-DIHYDROXYBENZYLAMINO)BENZOIC ACID
  • [2-HYDROXY-5-[N-(2',5'-DIHYDROXYBENZYL)AMINO]BENZOIC ACID
  • 5-(2,5-DIHYDROXYBENZYLAMINO)-2-HYDROXYBENZOIC ACID
  • 5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID
  • 5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID
  • 5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID
  • HDBA
  • COMPOUND 5
  • LAVENDUSTIN C
  • N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID
  • 2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid
  • Compound 5, HDBA, N-(2μ,5μ-Dihydroxybenzyl)-5-aminosalicylic acid, [2-Hydroxy-5-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoic acid
  • 5-(2,5-Dihydroxybenzylamino)salicylic acid, N-(2,5-Dihydroxybenzyl)-5-aminosalicylic acid
  • 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid
  • 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxy-benzoic acid
  • NSC 666251
  • N-(2-((2-((4Z,7Z,10Z,13Z,16Z,19Z)-DOCOSA-4,7,10,13,16,19-HEXAENAMIDO)ETHYL)DISULFANYL)-2-METHYLPROPYL)NICOTINAMIDE
  • Lavendustin C (HDBA)
  • Benzoic acid, 5-[[(2,5-dihydroxyphenyl)methyl]amino]-2-hydroxy-
  • HER1,ErbB-1,EGFR,inhibit,Inhibitor,Calmodulin-dependent protein kinases,calmodulin-dependent,Src,lavendustin C,pp60,CaMK,Ca2+,Epidermal growth factor receptor,tyrosine,kinase,Calmodulin-dependent kinases
  • 125697-93-0
  • Chelators
  • Cell Signaling and Neuroscience
  • Receptor Tyrosine Kinase Inhibitors
  • Tyrosine Kinase (TK)
  • Kinase/Phosphatase Biology
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Type
  • Enzyme Inhibitors
  • Cell Biology
  • BioChemical
  • Biochemicals and Reagents
  • Other enzyme inhibitors and activators
  • All Inhibitors
  • Inhibitors
  • Tyrosine Kinase Inhibitors