ChemicalBook > CAS DataBase List > MS 073
MS 073
- Product Name
- MS 073
- CAS No.
- 129716-45-6
- Chemical Name
- MS 073
- Synonyms
- MS 073;CP-162398;1-Piperazineethanol, 4-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-α-[(5-quinolinyloxy)methyl]-;1-(Quinolin-5-yloxy)-3-[4-[(10,11-dihydro-5H-dibenzo[a,d]cyclohepten)-5-yl]piperazin-1-yl]-2-propanol
- CBNumber
- CB51359621
- Molecular Formula
- C31H33N3O2
- Formula Weight
- 479.61
- MOL File
- 129716-45-6.mol
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MS 073 Chemical Properties,Usage,Production
Description
MS-073, also known as CP-162398, is a P-glycoprotein inhibitor (P-gp). MS-073 was compared with verapamil with regard to its ability to overcome MDR in vitro and in vivo. MS-073 at 0.1 microM almost completely reversed in vitro resistance to vincristine (VCR) in VCR-resistant P388 cells. MS-073 also reversed in vitro VCR, adriamycin (ADM), etoposide, and actinomycin D resistance in ADM-resistant human myelogenous leukemia K562 (K562/ADM) cells, MS-073 reverses MDR by competitively inhibiting drug binding to P-glycoprotein.
MS 073 Preparation Products And Raw materials
Raw materials
Preparation Products
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MS 073 Suppliers
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 19711
- Advantage
- 58
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19863
- Advantage
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- support@targetmol.com
- Country
- United States
- ProdList
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- Advantage
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129716-45-6, MS 073Related Search:
(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol
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MS 073
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