ChemicalBook > CAS DataBase List > Diethoxyacetonitrile

Diethoxyacetonitrile

Product Name: Diethoxyacetonitrile
CAS No.: 6136-93-2
Chemical Name: Diethoxyacetonitrile
Synonyms: Einecs 228-111-1;diethoxy-acetonitril;DIETHOXYACETONITRILE;Acetonitrile, diethoxy-;2,2-diethoxyacetonitrile;1,1-Diethoxyacetonitrile;Acetonitrile, 2,2-diethoxy-;2,2-Diethoxyacetonitrile,98%;DIETHOXYACETONITRILE ISO 9001：2015 REACH;China biggest manufacturer DIETHOXYACETONITRILE 6136-93-2
CBNumber: CB5136964
Molecular Formula: C6H11NO2
Formula Weight: 129.16
MOL File: 6136-93-2.mol

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Diethoxyacetonitrile Property

Melting point:: -19--18 °C (lit.)
Boiling point:: 167.7 °C/773 mmHg (lit.)
Density: 0.929 g/mL at 25 °C (lit.)
refractive index: n20/D 1.4(lit.)
Flash point:: 121 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: liquid
Appearance: Colorless to light yellow Liquid
InChI: InChI=1S/C6H11NO2/c1-3-8-6(5-7)9-4-2/h6H,3-4H2,1-2H3
InChIKey: UDELMRIGXNCYLU-UHFFFAOYSA-N
SMILES: C(#N)C(OCC)OCC
EPA Substance Registry System: Acetonitrile, diethoxy- (6136-93-2)

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Safety

Hazard Codes: Xn
Risk Statements: 10-20/21/22-36/37/38
Safety Statements: 16-26-27-36/37/39
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
HazardClass: 3.2
PackingGroup: III
HS Code: 2926907090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 370460
Product name: Diethoxyacetonitrile
Purity: 97%
Packaging: 5g
Price: $46.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 370460
Product name: Diethoxyacetonitrile
Purity: 97%
Packaging: 25g
Price: $61
Updated: 2025/07/31

TRC

Product number: D441990
Product name: Diethoxyacetonitrile
Packaging: 5g
Price: $85
Updated: 2021/12/16

Usbiological

Product number: 446756
Product name: Diethoxyacetonitrile
Packaging: 1g
Price: $319
Updated: 2021/12/16

AK Scientific

Product number: J90259
Product name: Diethoxyacetonitrile
Packaging: 1g
Price: $10
Updated: 2021/12/16

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Diethoxyacetonitrile Chemical Properties,Usage,Production

Uses

Diethoxyacetonitrile may be used in the preparation of methyl 5-diethoxymethylimidazole-4-carboxylate, via anionic cycloaddition reaction with methyl isocyanoacetate.

General Description

Diethoxyacetonitrile is a 2,2-dialkoxyalkanenitrile derivative. Reaction of hydrocyanic acid with various ortho esters of aliphatic and aromatic acids in the presence of acidic catalyst has been reported to afford diethoxyacetonitrile. Houben-Hoesch reaction of diethoxyacetonitrile with 1,2,4-trimethoxybenzene affords tris(2,4,5-trimethoxyphenyl)methane.

Synthesis

61189-99-9

6136-93-2

The general procedure for the synthesis of diethoxyacetonitrile from 2,2-diethoxyacetamide is as follows (cf. Inami, K., Shiba, T., Bull. Chem. Soc. Jpn., 1985, 58, 352): 2,2-diethoxyacetamide (7.13 g, 49.04 mmol) was dissolved in toluene (50 mL), followed by the addition of triethylamine (NEt3, 10.4 mL) and phosphorus pentoxide (P2O5, 9.04 g, 64.32 mmol). The reaction mixture was stirred for 1 hour. Upon completion of the reaction, the solvent was first removed by distillation at atmospheric pressure and then changed to reduced pressure distillation to collect the diethoxyacetonitrile to give a clear, colorless liquid product (4.049 g, 64% yield). The boiling point of the product was 100 °C (12-15 mmHg). IR spectra (KBr, cm^-1): 2983, 2937, 2896 (υC-H), 2247 (υC≡N), 1067 (δC-O). NMR hydrogen spectrum (CDCl3): δ 1.27 (6H, t, J = 8.0 Hz, 2 × CH3), 3.73 (4H, m, 2 × CH2), 5.31 (1H, s, CH). Low Resolution Mass Spectrometry (LREIMS): measured value 130.13 (M+H), calculated value C6H11NO2 129.08.

References

[1] Bulletin of the Chemical Society of Japan, 1985, vol. 58, # 1, p. 352 - 360
[2] Patent: WO2008/38018, 2008, A1. Location in patent: Page/Page column 63-64
[3] Journal of the American Chemical Society, 1947, vol. 69, p. 2660
[4] Journal of the American Chemical Society, 1947, vol. 69, p. 2660
[5] Chemische Berichte, 1934, vol. 67, p. 1507,1511

Diethoxyacetonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Diethoxyacetonitrile manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Diethoxyacetonitrile 6136-93-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-05-20

Hebei Chuanghai Biotechnology Co,.LTD

Product: DIETHOXYACETONITRILE 6136-93-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99.%
Supply Ability: 10 ton
Release date: 2024-08-21

Career Henan Chemical Co

Product: DIETHOXYACETONITRILE 6136-93-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-07-02

6136-93-2, DiethoxyacetonitrileRelated Search:

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diethoxy-acetonitril

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Acetonitrile, diethoxy-

Einecs 228-111-1

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DIETHOXYACETONITRILE ISO 9001：2015 REACH

China biggest manufacturer DIETHOXYACETONITRILE 6136-93-2

6136-93-2

C2H5O2CHCN

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Nitrogen Compounds

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Building Blocks

C6 to C7

Cyanides/Nitriles

Nitrogen Compounds