ChemicalBook > CAS DataBase List > BMS453

BMS453

Product Name
BMS453
CAS No.
166977-43-1
Chemical Name
BMS453
Synonyms
BMS453;BMS-189453 (BMS189453;(E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid;(E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid;4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid;Benzoic acid, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-;Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X receptors,BMS189453,arrest,cell,RARα,Retinoic acid receptors
CBNumber
CB51387459
Molecular Formula
C27H24O2
Formula Weight
380.48
MOL File
166977-43-1.mol
More
Less

BMS453 Property

Boiling point:
560.9±50.0 °C(Predicted)
Density 
1.167±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
pka
4.27±0.10(Predicted)
color 
white to beige
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1149
Product name
BMS-189453
Purity
≥98% (HPLC)
Packaging
5mg
Price
$132
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1149
Product name
BMS-189453
Purity
≥98% (HPLC)
Packaging
25mg
Price
$535
Updated
2024/03/01
Cayman Chemical
Product number
19076
Product name
BMS 453
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
19076
Product name
BMS 453
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
19076
Product name
BMS 453
Purity
≥98%
Packaging
10mg
Price
$178
Updated
2024/03/01
More
Less

BMS453 Chemical Properties,Usage,Production

Uses

BMS 453 is a synthetic retinoid and RARβ antagonist which also displays antagonist acitivity in RARα.

Definition

ChEBI: BMS-453 is a member of the class of dihydronaphthalenes that is 1,2-dihydronaphthalene which is substituted at positions 1, 1, 4, and 6 by methyl, methyl, phenyl, and 2-(p-carboxyphenyl)vinyl groups, respectively (the E isomer). It is a potent retinoic acid receptor gamma (RARbeta) agonist that acts as an antagonist against RARalpha and RARgamma. It has a role as a retinoic acid receptor beta agonist, a retinoic acid receptor gamma antagonist, a retinoic acid receptor alpha antagonist and a teratogenic agent. It is a member of dihydronaphthalenes, a member of benzoic acids and a stilbenoid.

BMS453 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

BMS453 Suppliers

EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58

166977-43-1, BMS453Related Search:


  • BMS453
  • 4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoicacid
  • (E)-4-[2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid
  • BMS-189453 (BMS189453
  • (E)-4-[2-(5,5-Dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)vinyl]benzoic acid
  • Benzoic acid, 4-[(1E)-2-(5,6-dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-
  • Inhibitor,BMS453,retinoid,RAR/RXR,inhibit,BMS-453,BMS 189453,TGFβ,breast,RARβ,RARγ,Retinoid X receptors,BMS189453,arrest,cell,RARα,Retinoic acid receptors
  • 166977-43-1