Deacetyltaxol

Product Name: Deacetyltaxol
CAS No.: 78432-77-6
Chemical Name: Deacetyltaxol
Synonyms: 10-DAT;10-O-deacetylpaclitaxel;10-DEP;DEACETYLTAXOL;10-DEACETYLTAXOL;10-Desacetyltaxol;Deacetyltaxol CAS;10-O-Deacetyltaxol;DEACETYLTAXOL, 10-;Deacetyl Paclitaxel
CBNumber: CB5139309
Molecular Formula: C45H49NO13
Formula Weight: 811.87
MOL File: 78432-77-6.mol

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Deacetyltaxol Property

Melting point:: 182-184?C
Boiling point:: 959.5±65.0 °C(Predicted)
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 11.31±0.70(Predicted)
color: White to Off-White
InChIKey: TYLVGQKNNUHXIP-ROFCLTHDNA-N

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Safety

Safety Statements: 24/25
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28503
Product name: 10-deacetyl Paclitaxel
Packaging: 5mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 28503
Product name: 10-deacetyl Paclitaxel
Packaging: 10mg
Price: $87
Updated: 2024/03/01

Cayman Chemical

Product number: 28503
Product name: 10-deacetyl Paclitaxel
Packaging: 25mg
Price: $179
Updated: 2024/03/01

Cayman Chemical

Product number: 28503
Product name: 10-deacetyl Paclitaxel
Packaging: 50mg
Price: $263
Updated: 2024/03/01

Usbiological

Product number: 299786
Product name: 10-Deacetyltaxol
Packaging: 10mg
Price: $566
Updated: 2021/12/16

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Deacetyltaxol Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Occurrence

A taxane derivative obtained from Catharanthus roseus.

Uses

A semi-synthetic precursor of Paclitaxel. Paclitaxel - impurity G.

Synthesis

7722-84-1

33069-62-4

78432-77-6

Example I Large-scale reaction of paclitaxel with NaHCO3: 500 mg (0.57 mmol) of paclitaxel was dissolved in 10 mL of THF and transferred to a 25 mL round-bottom flask equipped with a magnetic stirrer. To this solution, 10 mL of 30% H2O2 and 960.0 mg of NaHCO3 were sequentially added and the reaction mixture was stirred at room temperature overnight. After completion of the reaction, extraction was carried out using dichloromethane/water (50:50 v/v). The organic phases were combined and dried over anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure to give the crude product, which was further purified to obtain 457.2 mg 10-deacetylpaclitaxel in 96% yield. The product was analyzed by NMR and mass spectrometry, and the data were consistent with known samples.

References

[1] Patent: US5629433, 1997, A

Deacetyltaxol Preparation Products And Raw materials

Raw materials

Preparation Products

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Deacetyltaxol Suppliers

Canada 1 China 257 China Hong Kong 1 Europe 1 India 4 Japan 1 South Korea 1 Ukraine 1 United Kingdom 8 United States 28 Global 303

Nanjing Yuanzhi Biotechnology Co. Ltd.

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Jiangsu Yew Pharmaceutical Co., Ltd.

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J & K SCIENTIFIC LTD.

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Chembest Research Laboratories Limited

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Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
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XiaoGan ShenYuan ChemPharm co,ltd

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Country: China
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Wuhan Fortuna Chemical Co., Ltd

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BioBioPha Co., Ltd.

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Chengdu Biopurify Phytochemicals Ltd.

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Country: China
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Shanghai Winherb Medical Technology Co., Ltd.

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View Lastest Price from Deacetyltaxol manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Deacetyltaxol 78432-77-6
Price: US $0.00/g
Min. Order: 1g
Purity: 98%min
Supply Ability: 1000g
Release date: 2021-08-26

Shaanxi Haibo Biotechnology Co., Ltd

Product: Deacetyltaxol 78432-77-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-22

Shanghai Standard Technology Co., Ltd.

Product: Deacetyltaxol 78432-77-6
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-08

78432-77-6, DeacetyltaxolRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate N-ACETYL-L-TYROSINE ETHYL ESTER Tetraacetylethylenediamine 4,4'-Diacetylbiphenyl Paclitaxel CHLOROPHOSPHONAZO III Folic acid Stearic acid Hyaluronic acid DEACETYLTAXOL, 7-EPI-10-,7-EPI-10-DEACETYLTAXOL β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid (αR,βS)-(1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-Bis(acetyloxy)-4-[(benzoyloxy)Methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetraMethyl-12-oxo-6,10-Methanobenzocyclodecen-8-yl Ester Citric acid (2R,3S)-3-PHENYLISOSERINE ETHYLESTER Cephalomannine 7-Epitaxol Paclitaxel IMpurity F Baccatine III N-Debenzoyl-N-[(3E)-hex-3-enoyl]paclitaxel

10-DEACETYL PACLITAXEL

10-DEACETYLTAXOL

10-Desacetyl Paclitaxel

10-Desacetyltaxol

10-O-Deacetyltaxol

7-EPI-10-DEACETYL PACLITAXEL

DEACETYLTAXOL

b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester

10-DAT

b-(BenzoylaMino)-a-hydroxy-benzenepropanoicacid[2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetraMethyl-5

Paclitaxel EP Imurity G

Deacetyltaxol 78432-77-6

Paclitaxel Impurity 7（Paclitaxel EP Impurity G）

10-DEACETYLPACLITAXEL; 10-DEACETYLTAXOL; 10-DESACETYLTAXOL; 10-O-DEACETYLTAXOL

Paclitaxel EP Impurity G 10-O-deacetylpaclitaxel

Paclitaxel impurity 11/Paclitaxel EP Impurity G/10-Desacetyl Paclitaxel/[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-15-[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy-1,9,12-trihydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7

Paclitaxel impurity G

10-deacetyl taxol(7α-OH)

10-DEP

Benzenepropanoic acid, b-(benzoylaMino)-a-hydroxy-,(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetraMethyl-5-oxo-7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]ox

b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6

Deacetyltaxol 10-Desacetyltaxol

10-Desacetyl Paclitaxel (Paclitaxel EP Impurity G)

Paclitaxel EP impurity G

10-deacetyl taxol(10-DAT)

10-O-deacetylpaclitaxel

Deacetyl Paclitaxel

10-Desacetyl Paclitaxel 10-DAT

Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

Paclitaxel EP Impurity G (10-Desacetyl Paclitaxel)

10-Deacetyl PaclitaxelQ: What is 10-Deacetyl Paclitaxel Q: What is the CAS Number of 10-Deacetyl Paclitaxel Q: What is the storage condition of 10-Deacetyl Paclitaxel

78432-77-6 Deacetyltaxol

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate

4-(acetyloxy)-13α-[[(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl]oxy]-1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-en-2α-ylbenzoate(10-O-deacetylpaclitaxel)

Paclitaxel 10-deacetyl

DEACETYLTAXOL, 10-

Deacetyltaxol CAS

(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-acetoxy-9-(((2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoyl)oxy)-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H

10-Deacetyltaxol, 10 mM in DMSO

10-<i>O</i>-Deacetylpaclitaxel

Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-

Paclitaxel Imp. G (EP): 10-O-deacetylpaclitaxel

78432-77-6

C45H49NO13

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Intermediates & Fine Chemicals

Pharmaceuticals

Miscellaneous Biochemicals