Zinc acetate dihydrate Property

Melting point:

100 °C

Boiling point:

242-4°C

Density 

1.84

storage temp. 

Store at +5°C to +30°C.

solubility 

430g/l

form 

Solid

Specific Gravity

1.84

color 

White

Odor

Acetic acid odour

PH Range

6 - 8 at 50 g/l at 25 °C

PH

6.0-8.0 (25℃, 50mg/mL in H2O)

Water Solubility 

430 g/L (20 ºC)

Merck 

14,10128

BRN 

3732513

Stability:

Stable. Incompatible with alkalies, strong oxidizing agents.

InChIKey

BEAZKUGSCHFXIQ-UHFFFAOYSA-L

LogP

-0.285 (est)

CAS DataBase Reference

5970-45-6(CAS DataBase Reference)

NIST Chemistry Reference

Zinc acetate dihydrate(5970-45-6)

EPA Substance Registry System

Zinc acetate dihydrate (5970-45-6)

Safety

Hazard Codes 

Xn,N

Risk Statements 

22-36-50/53-50

Safety Statements 

26-60-61-36-57-39-29

RIDADR 

UN 3077 9/PG 3

WGK Germany 

3

RTECS 

ZG8750000

TSCA 

No

HazardClass 

9

PackingGroup 

III

HS Code 

29152900

Toxicity

LD50 orally in rats: 2.46 g/kg (Smyth)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Zinc acetate dihydrate Chemical Properties,Usage,Production

Chemical Properties

Zinc acetate occurs as white crystalline, lustrous plates with a faint acetic odor and an astringent taste.

Chemical Properties

Zinc acetate dihydrate Zn(C2H3O2)•2H2O is a Colourless or white efflorescent crystals; faint acetic acid odor; astringent taste; monoclinic crystals; density 1.735 g/cm3; loses water at 100°C; decomposes at 237°C; readily dissolves in water, 43g/100 mL at 20°C; soluble in alcohol.

Uses

Preserving wood; as mordant in dyeing; manufacture of glazes for painting on porcelain. As a reagent in testing for albumin, tannin, urobilin, phosphate, blood.

Uses

Zinc acetate [Zn(C2H3O2)2] is used as a mordant for dyeing cloth, as a wood preservative, as a laboratory agent, and as a dietary supplement.

Uses

Zinc acetate dihydrate is used in the preparation of layered Zn-arylphosphonates with potential application in sorption, ion exchange or catalysis and zinc sulfide nanoparticles coated on silica particles. It is used in dietary and medical applications. It is also used as lozenges for treating the common cold. It is used as a seeding material to grow zinc oxide nanorods on the microfibers of polyethylene terephthalate fabric. In addition, it finds application as wood preservation, production of other zinc salts, ethylene acetate manufacture, and an analytical reagent in various industries. As a plating inhibitor, it is used in nuclear power plant.

Uses

Zinc acetate is used as a mordant in dyeing textiles; in preserving wood; in manufacturing glazes for painting on ceramics; and as an analytic reagent in measuring albumin, tannin, and phosphate. Other uses are as a crosslinking agent for polymers; and as a supplement in food. The compound is used in medicine as an astringent.

Production Methods

Zinc acetate is synthesized by reacting zinc oxide with glacial acetic acid, with subsequent crystallization, separation by centrifugation, and drying and milling of the crystals. No organic solvents are used during the synthesis.

General Description

Structure of zinc acetate dehydrate is monoclinic with unit cell dimensions a=14.50, b=5.32 and c=11.02?.

Pharmaceutical Applications

Zinc acetate has been used as an excipient in a variety of pharmaceutical formulations including topical gels, lotions, and solutions, and subcutaneous injections. It has also been investigated for use in an oral controlled-release formulation for water-soluble drugs in combination with sodium alginate and xanthan gum.
Therapeutically, zinc acetate has been used in oral capsules for the treatment of Wilson’s disease. Zinc acetate has also been demonstrated to be effective as a spermicide in vaginal contraceptives.

Safety

Zinc acetate is used in topical pharmaceutical formulations and subcutaneous injections, where it is generally regarded as relatively nontoxic and nonirritant when used as an excipient. However, zinc acetate is poisonous by intravenous and intraperitoneal routes; it is also moderately toxic following oral consumption.
LD50 (mouse, IP): 0.108 g/kg
LD50 (mouse, oral): 0.287 g/kg
LD50 (rat, IP): 0.162 g/kg
LD50 (rat, oral): 0.794 g/kg

storage

Zinc acetate loses water of hydration above 100℃. Zinc acetate should be stored in an airtight container in a cool, dry, place.

Purification Methods

It crystallises (in poor yield) from hot water or, better, from EtOH. [Beilstein 2 III 193, 2 IV 114.]

Incompatibilities

Zinc acetate is incompatible with oxidizing agents, zinc salts, alkalis and their carbonates, oxalates, phosphates, and sulfides.

Regulatory Status

Included in the FDA Inactive Ingredients Database (SC injections; topical lotions and solutions). Included in medicines licensed in the UK.