ChemicalBook > CAS DataBase List > Reduced Coenzyme Q10

Reduced Coenzyme Q10

Product Name
Reduced Coenzyme Q10
CAS No.
992-78-9
Chemical Name
Reduced Coenzyme Q10
Synonyms
CoQH2-10;Ubiquinol;Ubiquinol 50;Liposomal QH;Water Soluble Q10;Dihydrocoenzyme Q10;Ubiquinol (1705334);Reduced Coenzyme Q10;Reduced ubiquinone-10;Reduced Ubiquinone Q10
CBNumber
CB51417992
Molecular Formula
C59H92O4
Formula Weight
865.36
MOL File
992-78-9.mol
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Reduced Coenzyme Q10 Property

Melting point:
48-49°C
Boiling point:
866.9±65.0 °C(Predicted)
Density 
0.951±0.06 g/cm3(Predicted)
storage temp. 
Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility 
Chloroform: soluble
form 
A crystalline solid
pka
10.53±0.50(Predicted)
InChIKey
QNTNKSLOFHEFPK-UPTCCGCDSA-N
SMILES
C1(O)=C(OC)C(OC)=C(O)C(C)=C1C/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(\C)/CC/C=C(/C)\C
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Safety

HS Code 
2909500000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19677
Product name
Ubiquinol
Purity
≥90%
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
19677
Product name
Ubiquinol
Purity
≥90%
Packaging
1mg
Price
$218
Updated
2024/03/01
Cayman Chemical
Product number
19677
Product name
Ubiquinol
Purity
≥90%
Packaging
5mg
Price
$961
Updated
2024/03/01
Cayman Chemical
Product number
19677
Product name
Ubiquinol
Purity
≥90%
Packaging
10mg
Price
$1681
Updated
2024/03/01
TRC
Product number
U700500
Product name
Ubiquinol
Packaging
1mg
Price
$65
Updated
2021/12/16
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Reduced Coenzyme Q10 Chemical Properties,Usage,Production

Description

Ubiquinol is a reduced form of coenzyme Q10 (CoQ10; ), which exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone/ubisemiquinone), and fully reduced (ubiquinol). CoQ10 acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc1 complex. CoQ10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis.

Chemical Properties

Light Yellow-Orange Solid

Uses

Reduced coenzyme Q for improving nervous system cell functions.

Definition

ChEBI: Ubiquinol-10 is a ubiquinol in which the polyprenyl substituent is decaprenyl. It has a role as a metabolite and a biomarker. It is a polyprenylhydroquinone and an ubiquinol.

benefits

The reduced form of CoQ10, ubiquinol, is a powerful lipid-soluble antioxidant that provides critical antioxidant protection in the lymph and blood throughout the body. Ubiquinol is the only known fat-soluble antioxidant that human cells can synthesize. In its reduced form, ubiquinol coenzyme Q10 plays a significant role in preventing oxidation in both the lipids that make up much of the structure of cellular membranes in cells throughout the body and also in lipoprotein lipids present in circulation. Coenzyme Q10 can also recycle or regenerate other antioxidants such as vitamin E7 and vitamin C. Ubiquinol plays a critical role in mitochondria by protecting mitochondrial membranes and mitochondrial DNA (mtDNA) from free radical damage[1].

Side effects

Coenzyme Q10 supplements appear to be safe and produce few side effects when taken as directed. Mild side effects might include digestive problems such as: Upper abdominal pain, Loss of appetite, Nausea and vomiting, and Diarrhea.
Other possible side effects may include Headaches and dizziness, Insomnia, Fatigue, Skin itching or rashes, and Irritability or agitation.

References

[1] Pelton, Ross. “Coenzyme Q10: A Miracle Nutrient Advances in Understanding.” Integrative medicine 19 2 (2020): 16–20.

Reduced Coenzyme Q10 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Reduced Coenzyme Q10 manufacturers

Baoji Guokang Bio-Technology Co., Ltd.
Product
UBIQUINOL 992-78-9
Price
US $145.00/KG
Min. Order
1KG
Purity
10%
Supply Ability
1000KG
Release date
2021-06-02
Zhuozhou Wenxi import and Export Co., Ltd
Product
UBIQUINOL 992-78-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
UBIQUINOL 992-78-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

992-78-9, Reduced Coenzyme Q10Related Search:


  • 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl -2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl- 1,4-benzenediol
  • Dihydrocoenzyme Q10
  • Reduced Coenzyme Q10
  • Reduced Ubiquinone Q10
  • Ubiquinol 50
  • UBIQUINOL (Reduced coenzyme Q10)
  • 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-DecaMethyl -2,6,10,14,18
  • 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecenyl]-5,6-dimethoxy-3-methylbenzene-1,4-diol
  • 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-Decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecenyl]-5,6-dimethoxy-3-methylhydroquinone
  • Reduced ubiquinone-10
  • Water Soluble Q10
  • Ubiquinol,Dihydrocoenzyme Q10
  • CoQH2-10
  • 1,4-Benzenediol, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-
  • Ubiquinol ,Ubidecarenone ,Coenzyme Q10
  • coenzyme Q10 (Ubiquinol)
  • Ubiquinol (1705334)
  • Coenzyme Q10-hydroquinone
  • Ubidecarenone Impurity 8 (Coenzyme Q10 H2)
  • Reduced CoQ10,CoQ10H2, Ubiquinol
  • Ubiquinol
  • Liposomal QH
  • Water-Soluble Ubiquinol
  • Coenzyme Q10 Impurity F
  • 992-78-9
  • C59H92O4
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Aromatics Compounds