5-METHYL-2H-ISOQUINOLIN-1-ONE
- Product Name
- 5-METHYL-2H-ISOQUINOLIN-1-ONE
- CAS No.
- 24188-72-5
- Chemical Name
- 5-METHYL-2H-ISOQUINOLIN-1-ONE
- Synonyms
- 5-Methylisoquinolin-1-ol;5-Methylisoquinolin-1(2H);5-METHYL-2H-ISOQUINOLIN-1-ONE;5-methylisoquinolin-1(2H)-one;5-methyl-1(2H)-isoquinolinone;5-Methyl-2H-Isoquinoline-1-one;1(2H)-Isoquinolinone, 5-methyl-;5-methyl-1,2-dihydroisoquinolin-1-one
- CBNumber
- CB5142505
- Molecular Formula
- C10H9NO
- Formula Weight
- 159.18
- MOL File
- 24188-72-5.mol
5-METHYL-2H-ISOQUINOLIN-1-ONE Property
- Boiling point:
- 400.5±45.0 °C(Predicted)
- Density
- 1.150±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 13.12±0.20(Predicted)
- Appearance
- Light yellow to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- Y5357
- Product name
- 5-Methylisoquinolin-1-ol
- Packaging
- 250mg
- Price
- $154
- Updated
- 2021/12/16
- Product number
- CHM0376350
- Product name
- 5-METHYL-2H-ISOQUINOLIN-1-ONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.89
- Updated
- 2021/12/16
- Product number
- A704276
- Product name
- 5-Methylisoquinolin-1(2H)-one
- Purity
- 97%
- Packaging
- 250mg
- Price
- $37
- Updated
- 2021/12/16
- Product number
- A704276
- Product name
- 5-Methylisoquinolin-1(2H)-one
- Purity
- 97%
- Packaging
- 1g
- Price
- $93
- Updated
- 2021/12/16
- Product number
- CM143617
- Product name
- 5-methylisoquinolin-1(2H)-one
- Purity
- 97%
- Packaging
- 1g
- Price
- $196
- Updated
- 2021/12/16
5-METHYL-2H-ISOQUINOLIN-1-ONE Chemical Properties,Usage,Production
Synthesis
872509-52-9
24188-72-5
Synthesis of Intermediate-3: 5-Methylisoquinolin-1(2H)-one: o-Methylcinnamoyl azide (Intermediate-2) (10 g, 53.5 mmol) was dissolved in toluene (100 mL) with stirring and heated to 110±2°C for 1 hour. After completion of the reaction, the toluene solvent was removed under reduced pressure, 1,2-dichlorobenzene (DCB) (100 mL) and iodine (catalytic amount) were added, and the reaction mixture was heated to 180±2°C and kept reacting overnight. At the end of the reaction, the solvent was removed under reduced pressure and the product was purified by recrystallization (ethyl acetate: hexane = 90:10) to afford the target compound 5-methylisoquinolin-1(2H)-one (4 g, 45% yield).
References
[1] Patent: US2013/178457, 2013, A1. Location in patent: Paragraph 0175
[2] Patent: WO2013/5168, 2013, A2. Location in patent: Page/Page column 33
[3] Journal of the Chemical Society - Perkin Transactions 1, 1997, # 8, p. 1147 - 1156
[4] Journal of Heterocyclic Chemistry, 2001, vol. 38, # 4, p. 961 - 964
5-METHYL-2H-ISOQUINOLIN-1-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-METHYL-2H-ISOQUINOLIN-1-ONE manufacturers
- Product
- 5-METHYL-2H-ISOQUINOLIN-1-ONE 24188-72-5
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-14
- Product
- 5-METHYL-2H-ISOQUINOLIN-1-ONE 24188-72-5
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 95%min
- Supply Ability
- 20kg/month
- Release date
- 2019-12-19