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N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

Product Name
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
CAS No.
42267-27-6
Chemical Name
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
Synonyms
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride;Lys-NCA;L-Lys(TFA)-NCA;Lysine-TFA-NCA;Creatinine Impurity 4;Meloxicam Impurity 25;L-LYS(TFA)-NCA(42267-27-6);e-Trifluoroacetyl-Lysine, NCA;-N-(4-(2,5-Dioxooxazolidin-4-yl);N-trifluoroacetyl lysine N-carboxyanhydride
CBNumber
CB51456876
Molecular Formula
C9H11F3N2O4
Formula Weight
268.19
MOL File
42267-27-6.mol
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N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Property

Melting point:
92-93℃ (DEC.)
Density 
1.377
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly)
pka
9.27±0.40(Predicted)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C9H11F3N2O4/c10-9(11,12)7(16)13-4-2-1-3-5-6(15)18-8(17)14-5/h5H,1-4H2,(H,13,16)(H,14,17)/t5-/m0/s1
InChIKey
KWNIHCJDDYRQFW-YFKPBYRVSA-N
SMILES
C(NCCCC[C@H]1C(=O)OC(=O)N1)(=O)C(F)(F)F
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Safety

HS Code 
2933.79.8500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical
Product number
D5600
Product name
(S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide
Packaging
1G
Price
$41
Updated
2024/03/01
TCI Chemical
Product number
D5600
Product name
(S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide
Packaging
5G
Price
$187
Updated
2024/03/01
TRC
Product number
T788530
Product name
N6-Trifluoroacetyl-L-lysineN-Carboxyanhydride
Packaging
1g
Price
$90
Updated
2021/12/16
TRC
Product number
T788530
Product name
N6-Trifluoroacetyl-L-lysineN-Carboxyanhydride
Packaging
2g
Price
$130
Updated
2021/12/16
TRC
Product number
T788530
Product name
N6-Trifluoroacetyl-L-lysineN-Carboxyanhydride
Packaging
10g
Price
$325
Updated
2021/12/16
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N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Chemical Properties,Usage,Production

Description

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride is a N6-trifluoroacetylated lysine derivative that is used in the synthesis of peptides. It is a racemic mixture of L and D forms, which is hydrolyzed to form L-glutamic acid, NH4Cl, and CO2. N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride has been shown to be useful in the formation of bonds between amino acids, such as lysine and dipeptides. The compound is also used for the protection of lysine against oxidation during peptide synthesis.

Chemical Properties

White to Off-White Solid

Uses

Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers. ?DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.

Uses

L-Lys(Tfa)-NCA (N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride) can be used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers.

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Suppliers

Americas 1 Canada 1 China 131 Europe 1 France 1 India 5 Japan 1 United States 7 Global 148
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
L-Lys(tfa)-NCA 42267-27-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%+
Supply Ability
1T
Release date
2024-01-18
Sichuan Jiaying Lai Technology Co.,LTD
Product
L-Lys(tfa)-NCA 42267-27-6
Price
US $1.00/g
Min. Order
10g
Purity
98%
Supply Ability
100kg
Release date
2019-07-14
Career Henan Chemical Co
Product
N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide 42267-27-6
Price
US $1.80-3.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
88KG
Release date
2019-09-04

42267-27-6, N6-Trifluoroacetyl-L-lysine N-CarboxyanhydrideRelated Search:

6-(TRIFLUOROACETYLAMINO)-1-HEXANOL N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride (4S)-4-Butyl-2-oxazolidinone N-6-Trifluoroacetyl-L-lysine

  • N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide
  • e-Trifluoroacetyl-Lysine, NCA
  • N-Trifluoroacetyl-L-lysine N-carboxyanhydride
  • N-(4-(2,5-Dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluoroacetamide
  • N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
  • L-Lysine-N-Trifluoroacetyl-N-Carboxyanhydride
  • (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetaMide
  • N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetaMide
  • AcetaMide,N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro-
  • N-[3-[(4S)-2,5-dioxooxazolidin-4-yl]propyl]-2,2,2-trifluoro-acetaMide
  • N-trifluoroacetyl lysine N-carboxyanhydride
  • 4-[(4S)-2,5-DIOXOOXAZOLIDIN-4-YL]BUTYL]-2,2,2-TRIFLUORO-ACETAMIDE
  • (S)-N-(4-(2,5-Dioxooxazolidin-4-yl)-butyl)-2,2,2-trifluoroacetamide
  • L-Lys(TFA)-NCA
  • Lys-NCA
  • -N-(4-(2,5-Dioxooxazolidin-4-yl)
  • L-LYS(TFA)-NCA(42267-27-6)
  • Lysine-TFA-NCA
  • N-[4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl]-2,2,2-trifluoroacetamide
  • Nepsilon-Trifluoroacetyl-Nalpha-carboxy-L-lysine Anhydride
  • Acetamide, N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifl...
  • Creatinine Impurity 4
  • Meloxicam Impurity 25
  • N6-(Trifluoroacetyl)-N2-carboxy-L-Lysine anhydride
  • Ne-trifluoroacetyl L-lysine intracyclic anhydride
  • 42267-27-6
  • C9H11F3N2O4
  • AMINOACIDS DERIVATIVES
  • Amino Acids & Derivatives
  • Aromatics
  • Chiral Reagents
  • Heterocycles