3-Bromo-4-hydroxy-5-nitropyridine
- Product Name
- 3-Bromo-4-hydroxy-5-nitropyridine
- CAS No.
- 31872-65-8
- Chemical Name
- 3-Bromo-4-hydroxy-5-nitropyridine
- Synonyms
- 5-BroM-3-nitro-4-pyridinol;3-broMo-5-nitro-4-pyridone;3-Bromo-5-nitro-4-pyridinol;4-Pyridinol, 3-broMo-5-nitro-;4-Hydroxy-3-nitro-5-broMopyridine;3-Bromo-4-hydroxy-5-nitropyridine;3-Bromo-5-nitro-4-hydroxy-pyridine;3-Bromo-4-hydroxy-5-nitropyridine ISO 9001：2015 REACH
- CBNumber
- CB51471185
- Molecular Formula
- C5H3BrN2O3
- Formula Weight
- 218.99
- MOL File
- 31872-65-8.mol
3-Bromo-4-hydroxy-5-nitropyridine Property
- Boiling point:
- 341.8±37.0 °C(Predicted)
- Density
- 2.006±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- -1.63±0.38(Predicted)
- color
- White to Light yellow to Light orange
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- ADE000723
- Product name
- 3-Bromo-5-nitropyridin-4-ol
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $308
- Updated
- 2023/06/20
- Product number
- B5287
- Product name
- 3-Bromo-4-hydroxy-5-nitropyridine
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $132
- Updated
- 2025/07/31
- Product number
- B5287
- Product name
- 3-Bromo-4-hydroxy-5-nitropyridine
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $402
- Updated
- 2025/07/31
- Product number
- B696233
- Product name
- 3-Bromo-4-hydroxy-5-nitropyridine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- FB153686
- Product name
- 3-Bromo-5-nitropyridin-4-ol
- Packaging
- 1g
- Price
- $57
- Updated
- 2021/12/16
3-Bromo-4-hydroxy-5-nitropyridine Chemical Properties,Usage,Production
Synthesis
5435-54-1
31872-65-8
Step 1. Synthesis of 3-bromo-5-nitropyridin-4-ol To a suspension of 4-hydroxy-3-nitropyridine (7.00 g, 50 mmol) in water (50 mL), bromine (3.23 mL, 63 mmol) was added slowly and dropwise at room temperature. The reaction mixture was stirred at room temperature for 1 hour, followed by heating to 50 °C and maintained for 2 hours. Upon completion of the reaction, the mixture was cooled to room temperature and stirring was continued for 1 hour. The solid product was collected by filtration, washed well with water and dried under vacuum for 2 days to afford 3-bromo-5-nitropyridin-4-ol 9.54 g in 87% yield.
References
[1] Patent: WO2005/37198, 2005, A2. Location in patent: Page/Page column 26
[2] Patent: WO2006/38773, 2006, A1. Location in patent: Page/Page column 57
[3] Patent: WO2005/37198, 2005, A2. Location in patent: Page/Page column 26
[4] Tetrahedron Letters, 2012, vol. 53, # 4, p. 377 - 379
[5] Journal of Medicinal Chemistry, 2014, vol. 57, # 6, p. 2462 - 2471
3-Bromo-4-hydroxy-5-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-4-hydroxy-5-nitropyridine Suppliers
- Tel
- 320-37350700
- Fax
- +32 (0)37350701
- sales@tcieurope.eu
- Country
- Europe
- ProdList
- 23671
- Advantage
- 75
View Lastest Price from 3-Bromo-4-hydroxy-5-nitropyridine manufacturers
- Product
- 3-Bromo-4-hydroxy-5-nitropyridine 31872-65-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-26
- Product
- 3-Bromo-4-hydroxy-5-nitropyridine 31872-65-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-26