1-PIPERAZIN-1-YL-ISOQUINOLINE

Product Name: 1-PIPERAZIN-1-YL-ISOQUINOLINE
CAS No.: 126653-00-7
Chemical Name: 1-PIPERAZIN-1-YL-ISOQUINOLINE
Synonyms: 1-PIPERAZIN-1-YL-ISOQUINOLINE;1-(1-piperazinyl)isoquinoline;1-Piperazine-1-yl-isoquinoline;Isoquinoline, 1-(1-piperazinyl)-
CBNumber: CB5148103
Molecular Formula: C13H15N3
Formula Weight: 213.28
MOL File: 126653-00-7.mol

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1-PIPERAZIN-1-YL-ISOQUINOLINE Property

Boiling point:: 417.7±25.0 °C(Predicted)
Density: 1.152±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 9.23±0.30(Predicted)

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Safety

HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: P992948
Product name: 1-Piperazine-1-Yl-Isoquinoline
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 072408
Product name: 1-Piperazine-1-yl-isoquinoline
Purity: 95+%
Packaging: 1g
Price: $462
Updated: 2021/12/16

AK Scientific

Product number: X9674
Product name: 1-(Piperazin-1-yl)isoquinoline
Packaging: 250mg
Price: $155
Updated: 2021/12/16

AK Scientific

Product number: X9674
Product name: 1-(Piperazin-1-yl)isoquinoline
Packaging: 1g
Price: $184
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0077627
Product name: 1-PIPERAZIN-1-YL-ISOQUINOLINE
Purity: 95.00%
Packaging: 1G
Price: $1085.7
Updated: 2021/12/16

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1-PIPERAZIN-1-YL-ISOQUINOLINE Chemical Properties,Usage,Production

Synthesis

110-85-0

19493-44-8

126653-00-7

Step 3: Synthesis of 1-(piperazin-1-yl)isoquinoline (2c) 1-Chloroisoquinoline (3 g, 18.3 mmol, 1 equiv) was dissolved in acetonitrile (150 mL) with piperazine (23.7 g, 274.5 mmol, 15 equiv) and potassium carbonate (3.8 g, 27.5 mmol, 1.5 equiv). The reaction mixture was heated to reflux for 48 hours. Upon completion of the reaction, the mixture was concentrated, diluted with dichloromethane (250 mL) and washed sequentially with saturated aqueous sodium bicarbonate and brine. The organic phase was separated, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford the target product 1-(piperazin-1-yl)isoquinoline 2c (3.9 g, 94% yield).LC-MS (M+H+): 214.1.

References

[1] Patent: WO2016/96631, 2016, A1. Location in patent: Page/Page column 27-28
[2] Patent: WO2016/96686, 2016, A1. Location in patent: Page/Page column 33-34
[3] Chemical and Pharmaceutical Bulletin, 2009, vol. 57, # 1, p. 34 - 42
[4] Journal of Medicinal Chemistry, 2010, vol. 53, # 3, p. 1023 - 1037

1-PIPERAZIN-1-YL-ISOQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-PIPERAZIN-1-YL-ISOQUINOLINE Suppliers

China 49 Germany 1 India 2 United Kingdom 1 United States 9 Global 62

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View Lastest Price from 1-PIPERAZIN-1-YL-ISOQUINOLINE manufacturers

Career Henan Chemical Co

Product: 1-PIPERAZIN-1-YL-ISOQUINOLINE 126653-00-7
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

126653-00-7, 1-PIPERAZIN-1-YL-ISOQUINOLINERelated Search:

1-PIPERAZIN-1-YL-ISOQUINOLINE

1-Piperazine-1-yl-isoquinoline

1-(1-piperazinyl)isoquinoline

Isoquinoline, 1-(1-piperazinyl)-

126653-00-7

pharmacetical

Quinoline&Isoquinoline