1-PIPERAZIN-1-YL-ISOQUINOLINE
- Product Name
- 1-PIPERAZIN-1-YL-ISOQUINOLINE
- CAS No.
- 126653-00-7
- Chemical Name
- 1-PIPERAZIN-1-YL-ISOQUINOLINE
- Synonyms
- 1-PIPERAZIN-1-YL-ISOQUINOLINE;1-(1-piperazinyl)isoquinoline;1-Piperazine-1-yl-isoquinoline;Isoquinoline, 1-(1-piperazinyl)-
- CBNumber
- CB5148103
- Molecular Formula
- C13H15N3
- Formula Weight
- 213.28
- MOL File
- 126653-00-7.mol
1-PIPERAZIN-1-YL-ISOQUINOLINE Property
- Boiling point:
- 417.7±25.0 °C(Predicted)
- Density
- 1.152±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 9.23±0.30(Predicted)
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- P992948
- Product name
- 1-Piperazine-1-Yl-Isoquinoline
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 072408
- Product name
- 1-Piperazine-1-yl-isoquinoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $462
- Updated
- 2021/12/16
- Product number
- X9674
- Product name
- 1-(Piperazin-1-yl)isoquinoline
- Packaging
- 250mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- X9674
- Product name
- 1-(Piperazin-1-yl)isoquinoline
- Packaging
- 1g
- Price
- $184
- Updated
- 2021/12/16
- Product number
- CHM0077627
- Product name
- 1-PIPERAZIN-1-YL-ISOQUINOLINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1085.7
- Updated
- 2021/12/16
1-PIPERAZIN-1-YL-ISOQUINOLINE Chemical Properties,Usage,Production
Synthesis
110-85-0
19493-44-8
126653-00-7
Step 3: Synthesis of 1-(piperazin-1-yl)isoquinoline (2c) 1-Chloroisoquinoline (3 g, 18.3 mmol, 1 equiv) was dissolved in acetonitrile (150 mL) with piperazine (23.7 g, 274.5 mmol, 15 equiv) and potassium carbonate (3.8 g, 27.5 mmol, 1.5 equiv). The reaction mixture was heated to reflux for 48 hours. Upon completion of the reaction, the mixture was concentrated, diluted with dichloromethane (250 mL) and washed sequentially with saturated aqueous sodium bicarbonate and brine. The organic phase was separated, dried over anhydrous sodium sulfate, and concentrated under reduced pressure to afford the target product 1-(piperazin-1-yl)isoquinoline 2c (3.9 g, 94% yield).LC-MS (M+H+): 214.1.
References
[1] Patent: WO2016/96631, 2016, A1. Location in patent: Page/Page column 27-28
[2] Patent: WO2016/96686, 2016, A1. Location in patent: Page/Page column 33-34
[3] Chemical and Pharmaceutical Bulletin, 2009, vol. 57, # 1, p. 34 - 42
[4] Journal of Medicinal Chemistry, 2010, vol. 53, # 3, p. 1023 - 1037
1-PIPERAZIN-1-YL-ISOQUINOLINE Preparation Products And Raw materials
Raw materials
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View Lastest Price from 1-PIPERAZIN-1-YL-ISOQUINOLINE manufacturers
- Product
- 1-PIPERAZIN-1-YL-ISOQUINOLINE 126653-00-7
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02