5-FLUORO-2-METHOXYNICOTINALDEHYDE
- Product Name
- 5-FLUORO-2-METHOXYNICOTINALDEHYDE
- CAS No.
- 351410-62-3
- Chemical Name
- 5-FLUORO-2-METHOXYNICOTINALDEHYDE
- Synonyms
- 3-Fluoro-2-methoxy-6-methylpyridine;uoro-2-methoxynicotinaL;-FLUORO-2-METHOXYNICOTINALDEHYDE;5-FLUORO-2-METHOXYNICOTINALDEHYDE;2-Methoxy-3-Fluoro-6-Methylpyridine;5-fluoro-2-Methoxypyridine-3-carbaldehyde;5-Fluoro-2-methoxy-pyridin-3-carbaldehyde;5-Fluoro-2-methoxy-3-pyridinecarbaldehyde;5-Fluoro-2-methoxypyridine-3-carboxaldehyde;5-Fluoro-2-methoxy-3-pyridine carboxyldehyde
- CBNumber
- CB5149201
- Molecular Formula
- C7H6FNO2
- Formula Weight
- 155.13
- MOL File
- 351410-62-3.mol
5-FLUORO-2-METHOXYNICOTINALDEHYDE Property
- Boiling point:
- 233.2±35.0 °C(Predicted)
- Density
- 1.266±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.82±0.20(Predicted)
- form
- Solid
- Appearance
- White to off-white Solid
- Sensitive
- Air & Moisture Sensitive
- InChI
- InChI=1S/C7H6FNO2/c1-11-7-5(4-10)2-6(8)3-9-7/h2-4H,1H3
- InChIKey
- YAGPZRLCMRMSFP-UHFFFAOYSA-N
- SMILES
- C1(OC)=NC=C(F)C=C1C=O
- CAS DataBase Reference
- 351410-62-3(CAS DataBase Reference)
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F401635
- Product name
- 5-Fluoro-2-methoxynicotinaldehyde
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- F401635
- Product name
- 5-Fluoro-2-methoxynicotinaldehyde
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- CS-0062015
- Product name
- 5-Fluoro-2-methoxypyridine-3-carbaldehyde
- Purity
- 99.71%
- Packaging
- 1g
- Price
- $61
- Updated
- 2021/12/16
- Product number
- PC50081
- Product name
- 5-Fluoro-2-methoxynicotinaldehyde
- Packaging
- 1g
- Price
- $74
- Updated
- 2021/12/16
- Product number
- 4H56-3-P9
- Product name
- 5-Fluoro-2-methoxynicotinaldehyde
- Packaging
- 1g
- Price
- $82
- Updated
- 2021/12/16
5-FLUORO-2-METHOXYNICOTINALDEHYDE Chemical Properties,Usage,Production
Synthesis
874822-98-7
351410-62-3
General procedure for the synthesis of 5-fluoro-2-methoxy-3-formylpyridine from 5-fluoro-3-hydroxymethyl-2-methoxypyridine: manganese(IV) dioxide (39.8 g, 458 mmol) was added to a 300 mL ethyl acetate solution of 5-fluoro-2-methoxy-pyridin-3-yl-methanol (36.8 g, 50.9 mmol), and the reaction mixture was at room temperature The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the diatomaceous earth pad was washed thoroughly with ethyl acetate. The filtrate and washings were combined and concentrated under reduced pressure to remove the solvent. The crude product was purified by silica gel column chromatography using 50% ethyl acetate in heptane solution as eluent to afford the target compound 5-fluoro-2-methoxy-3-formylpyridine as a light yellow solid (4.5 g, 29.0 mmol, 57.0% yield).
References
[1] Patent: US9096593, 2015, B2. Location in patent: Page/Page column 99
5-FLUORO-2-METHOXYNICOTINALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
5-FLUORO-2-METHOXYNICOTINALDEHYDE Suppliers
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View Lastest Price from 5-FLUORO-2-METHOXYNICOTINALDEHYDE manufacturers
- Product
- 5-FLUORO-2-METHOXYNICOTINALDEHYDE 351410-62-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-25
- Product
- 5-FLUORO-2-METHOXYNICOTINALDEHYDE 351410-62-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-18