5-Fluoro-2-methoxynicotinic acid
Uses- Product Name
- 5-Fluoro-2-methoxynicotinic acid
- CAS No.
- 884494-82-0
- Chemical Name
- 5-Fluoro-2-methoxynicotinic acid
- Synonyms
- 5-FLUORO-2-METHOXYNICOTINIC ACID;5-Fluoro-2-methoxypyridine-3-carboxylic acid;3-Pyridinecarboxylicacid, 5-fluoro-2-methoxy-;5-Fluoro-2-methoxynicotinic acid ISO 9001：2015 REACH;5-Fluoro-2-methoxypyridine-3-carboxylic acid, 3-Carboxy-5-fluoro-2-methoxypyridine
- CBNumber
- CB4458782
- Molecular Formula
- C7H6FNO3
- Formula Weight
- 171.13
- MOL File
- 884494-82-0.mol
5-Fluoro-2-methoxynicotinic acid Property
- Boiling point:
- 283.7±35.0 °C(Predicted)
- Density
- 1.386±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- 3.02±0.10(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C7H6FNO3/c1-12-6-5(7(10)11)2-4(8)3-9-6/h2-3H,1H3,(H,10,11)
- InChIKey
- WMTDYCWMCDHQHR-UHFFFAOYSA-N
- SMILES
- C1(OC)=NC=C(F)C=C1C(O)=O
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- F595813
- Product name
- 5-Fluoro-2-methoxynicotinicacid
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 104391
- Product name
- 5-Fluoro-2-methoxynicotinic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $79
- Updated
- 2021/12/16
- Product number
- PC10656
- Product name
- 5-Fluoro-2-methoxynicotinicacid
- Packaging
- 1g
- Price
- $118
- Updated
- 2021/12/16
- Product number
- 4H21-3-W4
- Product name
- 5-Fluoro-2-methoxynicotinic acid
- Packaging
- 1g
- Price
- $189
- Updated
- 2021/12/16
- Product number
- 104391
- Product name
- 5-Fluoro-2-methoxynicotinic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $238
- Updated
- 2021/12/16
5-Fluoro-2-methoxynicotinic acid Chemical Properties,Usage,Production
Uses
5-Fluoro-2-methoxynicotinic acid is used as a pharmaceutical and chemical intermediate.
Synthesis
351410-62-3
884494-82-0
In a round-bottomed flask, 5-fluoro-2-methoxypyridine-3-carbaldehyde (37, 0.500 g, 3.22 mmol) was dissolved in a solvent mixture of 30 mL of 1,4-dioxane and 10 mL of water, to which was added sodium chlorite (0.6734 g, 5.957 mmol) and sulfamic acid (2.39 g, 24.6 mmol) in that order. The reaction mixture was stirred at room temperature for 5 min and then poured into 100 mL of water and extracted with 100 mL of ethyl acetate. The organic layer was washed with water and brine sequentially, dried over anhydrous magnesium sulfate, filtered and the filtrate was concentrated in vacuum to give the crude product 5-fluoro-2-methoxynicotinic acid (150, 512 mg), which was used directly in the subsequent reaction.
References
[1] Patent: US9096593, 2015, B2. Location in patent: Page/Page column 321; 322
5-Fluoro-2-methoxynicotinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Fluoro-2-methoxynicotinic acid manufacturers
- Product
- 5-fluoro-2-methoxynicotinic acid 884494-82-0
- Price
- US $2.00-6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-08-06
- Product
- 5-Fluoro-2-methoxynicotinic acid 884494-82-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27
- Product
- 5-Fluoro-2-methoxynicotinic acid 884494-82-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-07-11