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5-Fluoro-2-hydroxypyridine

Product Name
5-Fluoro-2-hydroxypyridine
CAS No.
51173-05-8
Chemical Name
5-Fluoro-2-hydroxypyridine
Synonyms
5-Fluoropyridin-2-ol;5-Fluorpyridin-2-ol;5-Fluoro-2-pyridinol;uoro-2-hydroxypyridine;5-fluoro-1H-pyridin-2-one;5-Fluoropyridin-2(1H)-one;3-Fluoro-6-hydroxypyridine;5-FLUORO-2-HYDROXYPYRIDINE;2-HYDROXY-5-FLUOROPYRIDINE;2(1H)-Pyridinone, 5-fluoro-
CBNumber
CB3203611
Molecular Formula
C5H4FNO
Formula Weight
113.09
MOL File
51173-05-8.mol
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5-Fluoro-2-hydroxypyridine Property

Melting point:
150-155°C
Boiling point:
251.7±40.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
10.09±0.10(Predicted)
form 
Crystalline Powder
color 
White to off-white
InChIKey
KLULSYPVWLJZAO-UHFFFAOYSA-N
CAS DataBase Reference
51173-05-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-37/38-41
Safety Statements 
26-39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
753181
Product name
5-Fluoro-2-hydroxypyridine
Purity
97%
Packaging
1g
Price
$46.5
Updated
2023/06/20
TRC
Product number
F597988
Product name
5-Fluoro-2-hydroxypyridine
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
035690
Product name
5-Fluoro-2-hydroxypyridine
Purity
95+%
Packaging
5g
Price
$59
Updated
2021/12/16
BroadPharm
Product number
BP-11523
Product name
5-fluoropyridin-2-olhydrobromide
Packaging
5G
Price
$185
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
35270
Product name
5-Fluoro-2-hydroxypyridine
Purity
98%
Packaging
10g
Price
$445
Updated
2021/12/16
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5-Fluoro-2-hydroxypyridine Chemical Properties,Usage,Production

Uses

5-Fluoro-2-hydroxypyridine is a halogenated compound used in the synthesis of 5-Fluoro-2-hydroxy-3-nitropyridine and 5-halogenated pyrimidine compounds.

Synthesis

5-Fluoro-2-hydroxypyridine is synthesised using 5-fluoro-2-methoxypyridine as a raw material by chemical reaction. The specific synthesis steps are as follows:
A total of 4.6 L of toluene solution containing 3-80 was placed in several sealed tubes and treated with 900 ml of 35percent HCl at 145° C. for 2 hr. LC/MS showed no starting material, only 4. The toluene solution was decanted and discarded. The aqueous phase was washed with EtOAc and concentrated down to remove volatiles to afford a brown solid containing the desired fluoro-hydroxypyridine 4-80. [1488] A total of 244 g of this solid was collected and taken to next step as is (it was not completely dry). [1489] Note: We have subsequently run this by decanting the toluene layer first prior to heating to reduce volumes. Same reaction was carried out using HBr (48percent in H2O) at 100° C. for 6 h with similar result to the literature procedure 49percent yield. [1490] Ref: J. Heterocyclic Chem., 10, 779, 1973 (for above Reactions, Including Analytical Data).

5-Fluoro-2-hydroxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Fluoro-2-hydroxypyridine Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
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View Lastest Price from 5-Fluoro-2-hydroxypyridine manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
5-Fluoro-2-hydroxypyridine 51173-05-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2023-04-12
Henan Fengda Chemical Co., Ltd
Product
5-Fluoro-2-hydroxypyridine 51173-05-8
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Hebei Mojin Biotechnology Co., Ltd
Product
5-Fluoro-2-hydroxypyridine 51173-05-8
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-08-07

51173-05-8, 5-Fluoro-2-hydroxypyridineRelated Search:


  • 2-HYDROXY-5-FLUOROPYRIDINE
  • 5-FLUORO-2-HYDROXYPYRIDINE
  • 3-Fluoro-6-hydroxypyridine
  • 5-Fluoropyridin-2-ol
  • 5-Fluoropyridin-2(1H)-one
  • 5- fluoro-2-hydroxyl pyridine
  • 5-Fluoro-2-pyridinol
  • uoro-2-hydroxypyridine
  • 2(1H)-Pyridinone, 5-fluoro-
  • 5-Fluoro-2-hydroxypyridine ISO 9001:2015 REACH
  • 5-fluoro-1H-pyridin-2-one
  • 5-Fluorpyridin-2-ol
  • 51173-05-8
  • C5H4NOF
  • Fluorine series
  • blocks
  • FluoroCompounds
  • Pyridines
  • Pyridine
  • Fluorin-contained pyridine series