ChemicalBook > CAS DataBase List > 5-Fluoro-2-methoxynicotinic acid

5-Fluoro-2-methoxynicotinic acid

Uses

Product Name: 5-Fluoro-2-methoxynicotinic acid
CAS No.: 884494-82-0
Chemical Name: 5-Fluoro-2-methoxynicotinic acid
Synonyms: 5-FLUORO-2-METHOXYNICOTINIC ACID;5-Fluoro-2-methoxypyridine-3-carboxylic acid;3-Pyridinecarboxylicacid, 5-fluoro-2-methoxy-;5-Fluoro-2-methoxynicotinic acid ISO 9001：2015 REACH;5-Fluoro-2-methoxypyridine-3-carboxylic acid, 3-Carboxy-5-fluoro-2-methoxypyridine
CBNumber: CB4458782
Molecular Formula: C7H6FNO3
Formula Weight: 171.13
MOL File: 884494-82-0.mol

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5-Fluoro-2-methoxynicotinic acid Property

Boiling point:: 283.7±35.0 °C(Predicted)
Density: 1.386±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 3.02±0.10(Predicted)
Appearance: White to off-white Solid
InChI: InChI=1S/C7H6FNO3/c1-12-6-5(7(10)11)2-4(8)3-9-6/h2-3H,1H3,(H,10,11)
InChIKey: WMTDYCWMCDHQHR-UHFFFAOYSA-N
SMILES: C1(OC)=NC=C(F)C=C1C(O)=O

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: F595813
Product name: 5-Fluoro-2-methoxynicotinicacid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 104391
Product name: 5-Fluoro-2-methoxynicotinic acid
Purity: 98%
Packaging: 1g
Price: $79
Updated: 2021/12/16

Apolloscientific

Product number: PC10656
Product name: 5-Fluoro-2-methoxynicotinicacid
Packaging: 1g
Price: $118
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H21-3-W4
Product name: 5-Fluoro-2-methoxynicotinic acid
Packaging: 1g
Price: $189
Updated: 2021/12/16

Matrix Scientific

Product number: 104391
Product name: 5-Fluoro-2-methoxynicotinic acid
Purity: 98%
Packaging: 5g
Price: $238
Updated: 2021/12/16

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5-Fluoro-2-methoxynicotinic acid Chemical Properties,Usage,Production

Uses

5-Fluoro-2-methoxynicotinic acid is used as a pharmaceutical and chemical intermediate.

Synthesis

351410-62-3

884494-82-0

In a round-bottomed flask, 5-fluoro-2-methoxypyridine-3-carbaldehyde (37, 0.500 g, 3.22 mmol) was dissolved in a solvent mixture of 30 mL of 1,4-dioxane and 10 mL of water, to which was added sodium chlorite (0.6734 g, 5.957 mmol) and sulfamic acid (2.39 g, 24.6 mmol) in that order. The reaction mixture was stirred at room temperature for 5 min and then poured into 100 mL of water and extracted with 100 mL of ethyl acetate. The organic layer was washed with water and brine sequentially, dried over anhydrous magnesium sulfate, filtered and the filtrate was concentrated in vacuum to give the crude product 5-fluoro-2-methoxynicotinic acid (150, 512 mg), which was used directly in the subsequent reaction.

References

[1] Patent: US9096593, 2015, B2. Location in patent: Page/Page column 321; 322

5-Fluoro-2-methoxynicotinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-Fluoro-2-methoxynicotinic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-fluoro-2-methoxynicotinic acid 884494-82-0
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-06

Dideu Industries Group Limited

Product: 5-Fluoro-2-methoxynicotinic acid 884494-82-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-27

Career Henan Chemical Co

Product: 5-Fluoro-2-methoxynicotinic acid 884494-82-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-07-11

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5-Fluoro-2-methoxynicotinic acid ISO 9001：2015 REACH

884494-82-0

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