ChemicalBook > CAS DataBase List > 1-BENZYLPIPERIDINE-4-CARBONITRILE

1-BENZYLPIPERIDINE-4-CARBONITRILE

Product Name
1-BENZYLPIPERIDINE-4-CARBONITRILE
CAS No.
62718-31-4
Chemical Name
1-BENZYLPIPERIDINE-4-CARBONITRILE
Synonyms
OTAVA-BB 1369796;1-N-BENZYL-4-CYANOPIPERIDINE;1-Benzyl-4-piperidinecarbonitrile;1-BENZYLPIPERIDINE-4-CARBONITRILE;1-Benzylpiperidine-4-carbonitrile ,97%;4-Piperidinecarbonitrile, 1-(phenylMethyl)-
CBNumber
CB51511616
Molecular Formula
C13H16N2
Formula Weight
200.28
MOL File
62718-31-4.mol
More
Less

1-BENZYLPIPERIDINE-4-CARBONITRILE Property

Boiling point:
330.3±35.0 °C(Predicted)
Density 
1.06
storage temp. 
2-8°C
pka
6.95±0.10(Predicted)
More
Less

Safety

HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B288840
Product name
1-Benzyl-4-cyanopiperidine
Packaging
1g
Price
$250
Updated
2021/12/16
TRC
Product number
B288840
Product name
1-Benzyl-4-cyanopiperidine
Packaging
2.5g
Price
$455
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140419
Product name
1-Benzylpiperidine-4-carbonitrile
Packaging
10g
Price
$540
Updated
2021/12/16
Matrix Scientific
Product number
074344
Product name
1-Benzylpiperidine-4-carbonitrile
Purity
95+%
Packaging
5g
Price
$899
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0073444
Product name
1-BENZYLPIPERIDINE-4-CARBONITRILE
Purity
95.00%
Packaging
1G
Price
$958.65
Updated
2021/12/16
More
Less

1-BENZYLPIPERIDINE-4-CARBONITRILE Chemical Properties,Usage,Production

Uses

1-Benzylpiperidine-4-carbonitrile is an intermediate in organic synthesis and pharmaceutical intermediate for lab R&D.

Synthesis

Step 1 Preparation of intermediate 1-benzyl-4-carbonylamide piperidine

To piperidine-4-carboxamide (16.5 g, 0.13 mol ) and K2CO3 (35.6 g, 0.26 mol) in EtOH (350 ml) was added benzyl bromide (22.0 g, 0.13 mol) And heated to reflux for 3 h, cooled to room temperature and filtered. The filtrate was evaporated in vacuo and H2O (200ml) was added. The aqueous layer was extracted with CH2Cl2 (3×150ml), the organic layers were combined, and Na2SO4Dry and filter. The solvent was evaporated in vacuo to give the product as a white solid (20.0 g, 71.0%).

Step 2 Preparation of intermediate 1-benzyl-4-cyanopiperidine

1-benzyl-4-carbonylamide piperidine (20.0 g, 91.7 mmol) Mixed with P2O5 (16.92, 119.2 mmol) and heated under argon at 180-200°C for 3 h, cooled to room temperature and added H2O (150 ml). The aqueous solution was basified by the careful addition of K2CO3 and then extracted with EtOAc (3× 150 ml). The organic extract was dried over Na2SO4, filtered and the solvent evaporated in vacuo to give a yellow oil (16.7 g, 90.9%).

1-BENZYLPIPERIDINE-4-CARBONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-BENZYLPIPERIDINE-4-CARBONITRILE Suppliers

China 77 India 2 United Kingdom 1 United States 11 Global 91
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
ForeChem (Nantong) Technology Co.,Ltd.
Tel
513-85982855 18921614129
Fax
051385915507
Email
sales@xianxingpharm.com
Country
China
ProdList
2011
Advantage
61
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 17702719238
Email
sales@sun-shinechem.com
Country
China
ProdList
985
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
Shanghai AmasPharm Co., Ltd.
Tel
021-54540637 18621091017
Fax
021-34978309
Email
sales@amaspharm.com
Country
China
ProdList
731
Advantage
62
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3203
Advantage
55
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 15881143215
Email
liangli@happysyn.com
Country
China
ProdList
1849
Advantage
55
More
Less

View Lastest Price from 1-BENZYLPIPERIDINE-4-CARBONITRILE manufacturers

Career Henan Chemical Co
Product
1-BENZYLPIPERIDINE-4-CARBONITRILE 62718-31-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1lg; 2kg; 5kg; 10kg; 100kg
Release date
2019-08-31

62718-31-4, 1-BENZYLPIPERIDINE-4-CARBONITRILERelated Search:

1-BENZOYL-4-CYANO-4-PHENYLPIPERIDINE HYDROCHLORIDE 1-Benzyl-4-cyanopiperidine-4-carboxylic acid (1R,5S)-3-benzyl-3-azabicyclo[3.1.0]hexane-6-carbonitrile 1-BENZYLPIPERIDINE-4-CARBONITRILE 1-benzyl-4-(ethylamino)piperidine-4-carbonitrile N-BENZYL-4-CYANO-4-(1-PIPERIDINO)-PIPERIDINE, 98 1-BENZYL-4-CYANO-4-PIPERIDINECARBOXYLIC ACID ETHYL ESTER 4-AMINO-1-BENZYLPIPERIDINE-4-CARBONITRILE Piperidinium, 1-benzyl-4-cyano-1-methyl-4-phenyl-, iodide 1-BENZYL-4-CYANO-4-HYDROXYPIPERIDINE 4-ANILINO-1-BENZYL-4-CYANOPIPERIDINE 1-BENZYL-4-CYANO-4-(METHYLAMINO)-PIPERIDINE 1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride 1-Benzyl-4-(4-Methoxyphenyl)Piperidine-4-Carbonitrile Hydrochloride 1-(4-NITROBENZOYL)-4-PIPERIDINECARBONITRILE

  • OTAVA-BB 1369796
  • 4-Piperidinecarbonitrile, 1-(phenylMethyl)-
  • 1-Benzylpiperidine-4-carbonitrile ,97%
  • 1-BENZYLPIPERIDINE-4-CARBONITRILE
  • 1-N-BENZYL-4-CYANOPIPERIDINE
  • 1-Benzyl-4-piperidinecarbonitrile
  • 62718-31-4