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1-BENZYLPIPERIDINE-4-CARBONITRILE

Product Name
1-BENZYLPIPERIDINE-4-CARBONITRILE
CAS No.
62718-31-4
Chemical Name
1-BENZYLPIPERIDINE-4-CARBONITRILE
Synonyms
OTAVA-BB 1369796;1-N-BENZYL-4-CYANOPIPERIDINE;1-Benzyl-4-piperidinecarbonitrile;1-BENZYLPIPERIDINE-4-CARBONITRILE;1-Benzylpiperidine-4-carbonitrile ,97%;4-Piperidinecarbonitrile, 1-(phenylMethyl)-
CBNumber
CB51511616
Molecular Formula
C13H16N2
Formula Weight
200.28
MOL File
62718-31-4.mol
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1-BENZYLPIPERIDINE-4-CARBONITRILE Property

Boiling point:
330.3±35.0 °C(Predicted)
Density 
1.06
storage temp. 
2-8°C
pka
6.95±0.10(Predicted)
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Safety

HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B288840
Product name
1-Benzyl-4-cyanopiperidine
Packaging
1g
Price
$250
Updated
2021/12/16
TRC
Product number
B288840
Product name
1-Benzyl-4-cyanopiperidine
Packaging
2.5g
Price
$455
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140419
Product name
1-Benzylpiperidine-4-carbonitrile
Packaging
10g
Price
$540
Updated
2021/12/16
Matrix Scientific
Product number
074344
Product name
1-Benzylpiperidine-4-carbonitrile
Purity
95+%
Packaging
5g
Price
$899
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0073444
Product name
1-BENZYLPIPERIDINE-4-CARBONITRILE
Purity
95.00%
Packaging
1G
Price
$958.65
Updated
2021/12/16
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1-BENZYLPIPERIDINE-4-CARBONITRILE Chemical Properties,Usage,Production

Uses

1-Benzylpiperidine-4-carbonitrile is an intermediate in organic synthesis and pharmaceutical intermediate for lab R&D.

Synthesis

Step 1 Preparation of intermediate 1-benzyl-4-carbonylamide piperidine

To piperidine-4-carboxamide (16.5 g, 0.13 mol ) and K2CO3 (35.6 g, 0.26 mol) in EtOH (350 ml) was added benzyl bromide (22.0 g, 0.13 mol) And heated to reflux for 3 h, cooled to room temperature and filtered. The filtrate was evaporated in vacuo and H2O (200ml) was added. The aqueous layer was extracted with CH2Cl2 (3×150ml), the organic layers were combined, and Na2SO4Dry and filter. The solvent was evaporated in vacuo to give the product as a white solid (20.0 g, 71.0%).

Step 2 Preparation of intermediate 1-benzyl-4-cyanopiperidine

1-benzyl-4-carbonylamide piperidine (20.0 g, 91.7 mmol) Mixed with P2O5 (16.92, 119.2 mmol) and heated under argon at 180-200°C for 3 h, cooled to room temperature and added H2O (150 ml). The aqueous solution was basified by the careful addition of K2CO3 and then extracted with EtOAc (3× 150 ml). The organic extract was dried over Na2SO4, filtered and the solvent evaporated in vacuo to give a yellow oil (16.7 g, 90.9%).

1-BENZYLPIPERIDINE-4-CARBONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BENZYLPIPERIDINE-4-CARBONITRILE Suppliers

China 75 India 2 United Kingdom 1 United States 11 Global 89
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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JinYan Chemicals(ShangHai) Co.,Ltd.
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13817811078
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86-021-50426522,50426273
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sales@jingyan-chemical.com
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China
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Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
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United States
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WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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17702719238 17702719238
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sales@sun-shinechem.com
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China
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696;
Email
info@hanhongsci.com
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China
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China DongFan Chemical Co.,LTD
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86-0571-85151182
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86-0571-85151182
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China
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5700
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Shanghai AmasPharm Co., Ltd.
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021-54540637 18621091017
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China
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ZhengZhou HuaWen Chemical Co.Ltd
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0370-2785118 15343847665
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QQ：3470079902
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huawenchem@163.com
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China
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Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
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028-85114309 15881143215
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liangli@happysyn.com
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China
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T&W GROUP
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021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
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9900
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View Lastest Price from 1-BENZYLPIPERIDINE-4-CARBONITRILE manufacturers

Career Henan Chemical Co
Product
1-BENZYLPIPERIDINE-4-CARBONITRILE 62718-31-4
Price
US $1.00-1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1lg; 2kg; 5kg; 10kg; 100kg
Release date
2019-08-31

62718-31-4, 1-BENZYLPIPERIDINE-4-CARBONITRILERelated Search:

1-BENZOYL-4-CYANO-4-PHENYLPIPERIDINE HYDROCHLORIDE 1-Benzyl-4-cyanopiperidine-4-carboxylic acid (1R,5S)-3-benzyl-3-azabicyclo[3.1.0]hexane-6-carbonitrile 1-BENZYLPIPERIDINE-4-CARBONITRILE 1-benzyl-4-(ethylamino)piperidine-4-carbonitrile N-BENZYL-4-CYANO-4-(1-PIPERIDINO)-PIPERIDINE, 98 1-BENZYL-4-CYANO-4-PIPERIDINECARBOXYLIC ACID ETHYL ESTER 4-AMINO-1-BENZYLPIPERIDINE-4-CARBONITRILE Piperidinium, 1-benzyl-4-cyano-1-methyl-4-phenyl-, iodide 1-BENZYL-4-CYANO-4-HYDROXYPIPERIDINE 4-ANILINO-1-BENZYL-4-CYANOPIPERIDINE 1-BENZYL-4-CYANO-4-(METHYLAMINO)-PIPERIDINE 1-Benzyl-4-cyano-4-phenylpiperidine hydrochloride 1-Benzyl-4-(4-Methoxyphenyl)Piperidine-4-Carbonitrile Hydrochloride 1-(4-NITROBENZOYL)-4-PIPERIDINECARBONITRILE

  • OTAVA-BB 1369796
  • 4-Piperidinecarbonitrile, 1-(phenylMethyl)-
  • 1-Benzylpiperidine-4-carbonitrile ,97%
  • 1-BENZYLPIPERIDINE-4-CARBONITRILE
  • 1-N-BENZYL-4-CYANOPIPERIDINE
  • 1-Benzyl-4-piperidinecarbonitrile
  • 62718-31-4