ChemicalBook > CAS DataBase List > JKC-301
JKC-301
- Product Name
- JKC-301
- CAS No.
- 136553-96-3
- Chemical Name
- JKC-301
- Synonyms
- JKC-301;CYCLO(-D-ASP-PRO-D-ILE-LEU-D-TRP);JKC-301 Cyclo(-D-Asp-Pro-D-Ile-Leu-D-Trp);Cyclo(D-α-aspartyl-L-prolyl-D-isoleucyl-L-leucyl-D-tryptophyl);JKC 301 (CYCLO-[D-ASP-PRO-D-LLE-LEU-D-TR P]), SYNTHETIC, >99% PURITY
- CBNumber
- CB5152346
- Molecular Formula
- C32H44N6O7
- Formula Weight
- 624.73
- MOL File
- 136553-96-3.mol
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JKC-301 Property
- Boiling point:
- 1052.2±65.0 °C(Predicted)
- Density
- 1.31±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 4.04±0.10(Predicted)
- Sequence
- Cyclo({d-Asp}-Pro-{d-Ile}-Leu-{d-Trp})
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- PEP0001311
- Product name
- ETA-RECEPTOR ANTAGONIST [JKC-301]
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $697.34
- Updated
- 2021/12/16
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JKC-301 Chemical Properties,Usage,Production
Uses
JKC 301 is a selective Endothelin A receptor antagonist. JKC 301 attenuates the pressor effects of nicotine in rats. JKC 301 can be used to study cardiovascular disease caused by smoking[1][2].
References
[1] Tanus-Santos JE, Sampaio RC, Hyslop S, Franchini KG, Moreno H Jr. Endothelin ET(A) receptor antagonism attenuates the pressor effects of nicotine in rats. Eur J Pharmacol. 2000 May 12;396(1):33-7. DOI:10.1016/s0014-2999(00)00194-1
[2] Ngoka LC, et al. Location of alkali metal binding sites in endothelin A selective receptor antagonists, cyclo(D-Trp-D-Asp-Pro-D-Val-Leu) and cyclo(D-Trp-D-Asp-Pro-D-Ile-Leu), from multistep collisionally activated decompositions. J Mass Spectrom. 2000 Feb;35(2):265-76. DOI:10.1002/(SICI)1096-9888(200002)35:2<265::AID-JMS946>3.0.CO;2-#
JKC-301 Preparation Products And Raw materials
Raw materials
Preparation Products
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